Cetaphil DailyAdvance Ultra Hydrating Lotion Versus Vaseline Gluta-Hya Serum Burst Lotion Smoothing Perfector
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
HumectantHydrogenated Polyisobutene
EmollientCetearyl Alcohol
EmollientMacadamia Integrifolia Seed Oil
Skin ConditioningButyrospermum Parkii Butter
Skin ConditioningCyclopentasiloxane
EmollientAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingSodium Polyacrylate
AbsorbentPhenoxyethanol
PreservativeTocopheryl Acetate
AntioxidantCeteareth-20
CleansingStearoxytrimethylsilane
EmollientStearyl Alcohol
EmollientBenzyl Alcohol
PerfumingFarnesol
PerfumingSodium PCA
HumectantPanthenol
Skin ConditioningDimethiconol
EmollientCitric Acid
BufferingSodium Hydroxide
BufferingWater, Glycerin, Hydrogenated Polyisobutene, Cetearyl Alcohol, Macadamia Integrifolia Seed Oil, Butyrospermum Parkii Butter, Cyclopentasiloxane, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Polyacrylate, Phenoxyethanol, Tocopheryl Acetate, Ceteareth-20, Stearoxytrimethylsilane, Stearyl Alcohol, Benzyl Alcohol, Farnesol, Sodium PCA, Panthenol, Dimethiconol, Citric Acid, Sodium Hydroxide
Water
Skin ConditioningDimethicone
EmollientNiacinamide
SmoothingIsohexadecane
EmollientGlycerin
HumectantCarbomer
Emulsion StabilisingPropylene Glycol
HumectantLactic Acid
BufferingSalicylic Acid
MaskingGluconolactone
Skin ConditioningGlycolic Acid
BufferingCystine
MaskingGlycine
BufferingSodium PCA
HumectantGlutathione
Sodium Acetylated Hyaluronate
HumectantSodium Hyaluronate
HumectantSodium Hyaluronate Crosspolymer
HumectantHydrolyzed Sodium Hyaluronate
Skin ConditioningEthylhexylglycerin
Skin ConditioningPentylene Glycol
Skin ConditioningPetrolatum
EmollientPhenoxyethanol
PreservativeMethylparaben
PreservativeParfum
MaskingSodium Hydroxide
BufferingTitanium Dioxide
Cosmetic ColorantAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingDisodium EDTA
Water, Dimethicone, Niacinamide, Isohexadecane, Glycerin, Carbomer, Propylene Glycol, Lactic Acid, Salicylic Acid, Gluconolactone, Glycolic Acid, Cystine, Glycine, Sodium PCA, Glutathione, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Ethylhexylglycerin, Pentylene Glycol, Petrolatum, Phenoxyethanol, Methylparaben, Parfum, Sodium Hydroxide, Titanium Dioxide, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Disodium EDTA
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
Learn more about Acrylates/C10-30 Alkyl Acrylate CrosspolymerGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideSodium PCA is the sodium salt of pyroglutamic acid. It is naturally occurring in our skin's natural moisturizing factors where it works to maintain hydration.
The PCA stands for pyrrolidone carboxylic acid, a natural amino acid derivative.
This ingredient has skin conditioning, anti-inflammatory, and humectant properties. Humectants help hydrate your skin by drawing moisture from the air. This helps keep your skin moisturized.
Learn more about Sodium PCAWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water