Avène XeraCalm A.D Soothing Concentrate Versus Avène Cicalfate+ Multi Protective Restorative Cream SPF50+
This calming moisturizer is formulated around Aquaphilus Dolomiae Extract and Oenothera Biennis Oil to calm redness and strengthen the skin barrier.
This barrier-repair day moisturizer is formulated around Hydroxyacetophenone and Panthenol to strengthen the skin barrier and calm redness.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningCaprylic/Capric Triglyceride
MaskingGlycerin
HumectantCetearyl Alcohol
EmollientAquaphilus Dolomiae Extract
Skin ConditioningArginine
MaskingCetearyl Glucoside
EmulsifyingCetyl Alcohol
EmollientCitric Acid
BufferingEvening Primrose Oil/Palm Oil Aminopropanediol Esters
Skin ConditioningGlyceryl Stearate
EmollientGlycine
BufferingOenothera Biennis Oil
EmollientPEG-100 Stearate
SurfactantPolyacrylate-13
Polyisobutene
Polysorbate 20
EmulsifyingSorbitan Isostearate
EmulsifyingTocopherol
AntioxidantTocopheryl Acetate
AntioxidantWater, Caprylic/Capric Triglyceride, Glycerin, Cetearyl Alcohol, Aquaphilus Dolomiae Extract, Arginine, Cetearyl Glucoside, Cetyl Alcohol, Citric Acid, Evening Primrose Oil/Palm Oil Aminopropanediol Esters, Glyceryl Stearate, Glycine, Oenothera Biennis Oil, PEG-100 Stearate, Polyacrylate-13, Polyisobutene, Polysorbate 20, Sorbitan Isostearate, Tocopherol, Tocopheryl Acetate
Ethylhexyl Salicylate
UV AbsorberDiethylamino Hydroxybenzoyl Hexyl Benzoate
UV FilterEthylhexyl Triazone
UV AbsorberBis-Ethylhexyloxyphenol Methoxyphenyl Triazine
UV AbsorberTris-Biphenyl Triazine
UV AbsorberHydroxyacetophenone
AntioxidantPhenoxyethanol
PreservativeWater
Skin ConditioningDibutyl Adipate
EmollientGlycerin
HumectantPotassium Cetyl Phosphate
EmulsifyingStearic Acid
CleansingPanthenol
Skin ConditioningVp/Acrylates/Lauryl Methacrylate Copolymer
Xanthan Gum
EmulsifyingDecyl Glucoside
CleansingCeramide NP
Skin ConditioningSodium Phytate
Sodium Hydroxide
BufferingButylene Glycol
HumectantDisodium Phosphate
BufferingTocopheryl Acetate
AntioxidantAloe Barbadensis Leaf Juice
Skin ConditioningAlcohol
AntimicrobialCitric Acid
BufferingEthylhexyl Salicylate, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Ethylhexyl Triazone, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Tris-Biphenyl Triazine, Hydroxyacetophenone, Phenoxyethanol, Water, Dibutyl Adipate, Glycerin, Potassium Cetyl Phosphate, Stearic Acid, Panthenol, Vp/Acrylates/Lauryl Methacrylate Copolymer, Xanthan Gum, Decyl Glucoside, Ceramide NP, Sodium Phytate, Sodium Hydroxide, Butylene Glycol, Disodium Phosphate, Tocopheryl Acetate, Aloe Barbadensis Leaf Juice, Alcohol, Citric Acid
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.
Learn more about Citric AcidGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinTocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Learn more about Tocopheryl AcetateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water