Avène Cicalfate+ Multi Protective Restorative Cream SPF50+
A day moisturizer with 25 ingredients, including spf, vitamin E, and ceramides.
Overview
What it is
Day moisturizer with 25 ingredients that contains ceramides, SPF and Vitamin E
Suited For
It has ingredients that are good for anti aging, dry skin, brightening skin, sensitive skin and scar healing
Free From
It doesn't contain any common allergens, fragrances, oils, parabens, silicones or sulfates
Fun facts
Avène is from France. This product is used in 13 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Ethylhexyl Salicylate
UV AbsorberDiethylamino Hydroxybenzoyl Hexyl Benzoate
UV FilterEthylhexyl Triazone
UV AbsorberBis-Ethylhexyloxyphenol Methoxyphenyl Triazine
Skin ConditioningTris-Biphenyl Triazine
UV AbsorberHydroxyacetophenone
AntioxidantPhenoxyethanol
PreservativeWater
Skin ConditioningDibutyl Adipate
EmollientGlycerin
HumectantPotassium Cetyl Phosphate
EmulsifyingStearic Acid
CleansingPanthenol
Skin ConditioningVp/Acrylates/Lauryl Methacrylate Copolymer
Xanthan Gum
EmulsifyingDecyl Glucoside
CleansingCeramide NP
Skin ConditioningSodium Phytate
Sodium Hydroxide
BufferingButylene Glycol
HumectantDisodium Phosphate
BufferingTocopheryl Acetate
AntioxidantAloe Barbadensis Leaf Juice
Skin ConditioningAlcohol
AntimicrobialCitric Acid
BufferingEthylhexyl Salicylate, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Ethylhexyl Triazone, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Tris-Biphenyl Triazine, Hydroxyacetophenone, Phenoxyethanol, Water, Dibutyl Adipate, Glycerin, Potassium Cetyl Phosphate, Stearic Acid, Panthenol, Vp/Acrylates/Lauryl Methacrylate Copolymer, Xanthan Gum, Decyl Glucoside, Ceramide NP, Sodium Phytate, Sodium Hydroxide, Butylene Glycol, Disodium Phosphate, Tocopheryl Acetate, Aloe Barbadensis Leaf Juice, Alcohol, Citric Acid
Key Ingredients
Benefits
Concerns
Ingredients Explained
Ethylhexyl Salicylate is an organic compound used to block UV rays. It primarily absorbs UVB rays but offers a small amount of UVA protection as well.
Commonly found in sunscreens, Ethylhexyl Salicylate is created from salicylic acid and 2-ethylhexanol. You might know salicylic acid as the effective acne fighter ingredient and BHA.
The ethylhexanol in this ingredient is a fatty alcohol and helps hydrate your skin, similar to oils. It is an emollient, which means it traps moisture into the skin.
According to manufacturers, Ethylhexyl Salicylate absorbs UV wavelength of 295-315 nm, with a peak absorption at 307-310 nm. UVA rays are linked to long term skin damage, such as hyperpigmentation. UVB rays emit more energy and are capable of damaging our DNA. UVB rays cause sunburn.
Learn more about Ethylhexyl SalicylateDiethylamino Hydroxybenzoyl Hexyl Benzoate (DHHB) is a chemical UV-A absorber. It is formulated for high UVA protection (320-400 nm).
DHHB is well-liked for:
DHHB has been approved by the EU, Japan, Taiwan, and South America for use up to 10%. Unfortunately, it has not been approved for use in the US or Canada due to slow regulatory processes.
This ingredient is soluble in oils, fats, and lipids.
Learn more about Diethylamino Hydroxybenzoyl Hexyl BenzoateEthylhexyl Triazone is a modern chemical sunscreen that protects from UV-B radiation.
It is the most effective of existing UV-B filters, as it provides the highest level of photo-stable absorption. It protects from the entire UV-B range (280 to 320nm), with it's highest level of protection at 314nm.
Ethylhexyl Triazone is oil soluble, oderless and colorless, which mean it is able to be incorporated into a variety of different formulations.
It is not currently available within the United States due to slow changing FDA regulations. Outside of the US, it is used in formulations at concentrations up to 5%.
Learn more about Ethylhexyl TriazoneYou might know this ingredient as Tinosorb S or Bemotrizinol. It is a UV filter that covers both UVA and UVB rays.
This ingredient has two peak UV absorption peaks ( 310 and 340 nm) and is able to absorb both UV-A and UV-B rays. This ingredient works by preventing UV rays from reaching and damaging your skin.
On top of that - it is highly photostable and helps prevent the photodegration of other sunscreen ingredients such as avobenzone.
Tinosorb S is allowed in the EU, Australia, and Asia. It is close to being approved by the FDA and we'll hopefully get this ingredient in the U.S. by late 2026.
Fun fact: Tinosorb S is the most effective UV absorber at maximum concentration (measured by SPF) permitted in the EU.
This ingredient is oil-soluble, so your oil-cleansers will take this right off at night.
Learn more about Bis-Ethylhexyloxyphenol Methoxyphenyl TriazineTinosorb A2B is a UV-B and UV-A sunscreen filter (290 - 340 nm). This ingredient is photo-stable and water-soluble.
According to studies done by the manufacturer, it is the most effective UVB and UV-A 2 sunscreen filter to date.
It is mostly effective at protecting in the UV-A 2 (315-340 nm) range but has a boosting effect in the UV-A 1 (340 - 400 nm) range.
This ingredient is currently available in the EU and Asia, but is awaiting approval in the US and Canada.
Learn more about Tris-Biphenyl TriazineHydroxyacetophenone is antioxidant with skin conditioning and soothing properties. It also boosts the efficiency of preservatives.
Though naturally occuring in Norwegian spruce needles, this ingredient is usually synthetically created.
This ingredient is not irritating or sensitizing. Recent research also suggests it may have skin-brightening effects through tyrosinase inhibition.
Learn more about HydroxyacetophenonePhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterDibutyl Adipate is an emollient and solvent. It is created from butyl alcohol and adipic acid.
As a solvent, Dibutyl Adipate helps mix and disperse ingredients evenly.
Dibutyl Adipate is soluble in water and organic solvents. It does not absorb UV rays.
Learn more about Dibutyl AdipateGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPotassium Cetyl Phosphate is the potassium salt of a mixture. This mixture consists of the esters from phosphoricacid and cetyl alcohol.
Potassium Cetyl Phosphate is an emulsifier and cleansing agent. Emulsifiers help stabilize a product. It does this by preventing certain ingredients from separating.
As a cleansing agent, Potassium Cetyl Phosphate helps gather oils, dirts, and pollutants from your skin. This makes it easier to rinse them away with water.
Learn more about Potassium Cetyl PhosphateStearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.
In cosmetics, it is a multitasker:
Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.
Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.
Learn more about Stearic AcidPanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolWe don't have a description for Vp/Acrylates/Lauryl Methacrylate Copolymer yet.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumDecyl Glucoside is a plant-derived surfactant and emulsion stabilizer. It is created by reacting glucose with the fatty acids from plants.
Like all surfactants, it works by lowering the surface tension between water and oil. This makes it so that dirt, sebum, and makeup can be lifted off your skin and rinsed away. It also produces a dense and creamy foam.
Because it has a neutral charge, it is compatible with a wide range of ingredients and stays stable across a broad pH range/water hardiness conditions.
Patch testing has shown it to have the lowest irritation potential among common cleansing surfactants (like SLS).
Typical use levels range from 5-20% in rinse-off cleansers.
One thing worth knowing: The American Contact Dermatitis Society named the parent family, alkyl glucosides, "Allergen of the Year" in 2017. The prevalence of allergy is pretty low but be sure to patch test if you've reacted to "gentle" or sulfate-free cleansers before.
This ingredient is fungal acne safe because the fatty alcohol portion of this ingredient is below the C11-24 chain length that Malassezia can metabolize.
Learn more about Decyl GlucosideCeramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Learn more about Ceramide NPSodium Phytate is the synthetic salt form of phytic acid. Phytic acid is an antioxidant and can be found in plant seeds.
Sodium Phytate is a chelating agent. Chelating agents help prevent metals from binding to water. This helps stabilize the ingredients and the product.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolDisodium Phosphate is a water-soluble powder used as a pH adjuster and mild chelating agent. It basically holds a specific pH and binds stray metal ions so your product stays stable.
This ingredient is usually used at very low levels and concentrations range from 0.000054% - 2.9%. The CIR Expert Panel states this ingredient to be non-irritating at current use levels.
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateAloe Barbadensis Leaf Juice comes from leaves of the aloe plant. Aloe Barbadensis Leaf Juice is best known for helping to soothe sunburns. It is also anti-inflammatory, moisturizing, antiseptic, and can help heal wounds.
Aloe is packed with good stuff including Vitamins A, C, and E. These vitamins are antioxidants, which help fight free-radicals and the damage they may cause. Free-radicals are molecules that may damage your skin cells, such as pollution.
Aloe Barbadensis Leaf Juice also contains sugars. These sugars come in the form of monosaccharides and polysaccharides, folic acid, and choline. These sugars are able to help bind moisture to skin.
It also contains minerals such as calcium, 12 anthraquinones, fatty acids, amino acids, and Vitamin B12.
Learn more about Aloe Barbadensis Leaf JuiceThis ingredient is also called ethanol or ethyl alcohol. It is denatured, meaning made undrinkable for cosmetic use.
In formulas, it:
Is it bad for your skin?
The answer comes down to concentration. Patch and wash studies have found highly concentrated alcohol-based hand rubs (60-100%) cause less barrier disruption than washing with a basic detergent like SLS. The only measurable effect in these studies was a temporary dip in skin hydration.
Concentrations below 12-15% in leave-on cosmetics is generally well-tolerated. Concentrations above start to see increased transepidermal water loss (TEWL) and reduced hydration.
In concentrations about 58%, it creates temporary channels in your skin's lipid layers to become more permeable and allow other ingredients to slip through easily.
This ingredient can be up to 80% of the formula in alcohol-based perfumes.
Overall, this ingredient is probably harmless if found lower down an ingredients list but worth side-eyeing if it's high up (especially if your barrier is already struggling).
Alcohol can worsen dry skin, eczema, and oily skin, especially at higher concentrations. This is because it can increase transepidermal water loss and decrease hydration to disrupt the skin barrier.
According to the National Rosacea Society based in the US, you should be mindful of products with these alcohols in the top half of ingredients.
True allergic contact dermatitis to ethanol is uncommon, but be sure to patch test if you have dry or sensitive skin.
Learn more about AlcoholCitric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidReviews
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Where it's from
Avène is a French brand
50 SPF Rating
With an SPF rating of 50, this product protects against 98.0% of UVB rays
Often compared with
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Read more about us· Updated November 5, 2025 • Added by larrieeee