Uriage Dépiderm Anti-Dark Spot Intensive Care

Uriage Dépiderm Anti-Dark Spot Intensive Care

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Overview

What it is

Facial treatment with 31 ingredients that contains AHA, niacinamide, Vitamin C and Vitamin E

Cool Features

It is reef safe

Suited For

It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates

Fun facts

Uriage is from France.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

What's inside (and what isn't)

Ingredients List

Dive into the full list of ingredients.

Key Ingredients

Benefits

Concerns

Ingredients Explained

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Emollient, Skin Conditioning

We don't have a description for Di-C12-13 Alkyl Malate yet.

Emollient, Skin Conditioning, Solvent

Dicaprylyl Ether is created from caprylic acid. It is a texture-enhancer and emollient.

As an emollient, Dicaprylyl Ether is non-comedogenic. It helps soften and smooth the skin by creating a barrier on top. This barrier helps trap moisture in, helping to hydrate the skin.

Dicaprylyl Ether gives a non-greasy feel and better spreadability to products.

Learn more about Dicaprylyl Ether
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emollient, Skin Conditioning

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan?

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Is squalane an oil?

Squalane is often called an oil, but it’s technically not; it’s a hydrocarbon, meaning it’s only made of carbon and hydrogen, unlike true oils which are triglycerides made of fatty acids and glycerol.

The term “oil-free” isn’t regulated, so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

While some people avoid oils thinking they cause breakouts, the right kind of oil (or oil-like ingredient like squalane) can actually help balance and hydrate your skin. It’s worth testing out simple oils or squalane to see what works best for your skin.

Learn more about Squalane
Antioxidant, Emollient, Skin Conditioning

Ascorbyl Tetraisopalmitate is a version of ascorbic acid, or Vitamin C.

This ingredient has many benefits including reducing wrinkles, skin soothing, dark spot fading, and fighting against free radicals.

It helps with dark spot fading by interfering with the process of skin darkening, helping to reduce hyperpigmentation. Like other forms of vitamin C, this ingredient encourages the skin to create more collagen.

As an antioxidant, it helps fight free-radicals. Free-radicals are molecules that may damage your skin cells.

One study found Ascorbyl Tetraisopalmitate to degrade in sunlight, but is stabilized when combined with acetyl zingerone.

Learn more about Ascorbyl Tetraisopalmitate
Buffering

Glycolic Acid is arguably the most famous AHA with a ton of research to back up its benefits.

Its main role is to remove the top layer of dead skin cells, allowing newer skin cells to emerge.

Specifically, AHAs work by breaking down the structural "glue" holding the old skin cells in place. Getting rid of the old skin cells allows skin to regenerate newer skin cells in its place. A build up of dead skin cells can lead to tired and dull looking skin.

Due to this, glycolic acid helps with:

Fun fact: Glycolic acid increases skin hydration by playing a role in creating molecules that create hyaluronic acid naturally.

When starting glycolic Acid, it is normal to feel slight stinging.

The pH value and concentration of glycolic acid play a role in the effectiveness of the product. Concentrations between 5-20% glycolic acid have been shown to be effective in clinical studies.

Recent studies have shown Glycolic Acid may protect the skin against UV damage. However, you should always wear SPF, especially when using exfoliants.

Read more about some other popular AHA's here:

Learn more about Glycolic Acid
Emulsifying

Steareth-2 is a waxy compound used to emulsify ingredients. It is created from polyethylene glycol and stearyl alcohol.

The 2 stands for the number of ethylene oxide units used to create this ingredient.

Cleansing, Emulsifying

We don't have a description for Steareth-21 yet.

Buffering, Humectant, Skin Conditioning

Lactic Acid is an AHA that is derived from fermenting lactose, a carbohydrate from milk. It removes the top layer of old and dead skin cells and helps increase cell turnover.

Benefits of Lactic Acid are that it can help to reduce large pores and reduce the effects of aging. Some potential downsides are that it can be bad for dry skin, cause irritation, worsen eczema, and worsen rosacea.

Not only does it help exfoliate the skin, it helps strengthen the skin's barrier. When applied, lactic acid helps the skin create ceramides.

Lactic acid is an over-the-counter chemical exfoliant that comes from the fermentation of lactose — a carbohydrate found in milk.

Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.

Read more about some other popular AHA's here:

Learn more about Lactic Acid
Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Learn more about Sodium Hydroxide
Absorbent, Emulsion Stabilising, Skin Conditioning

Maltodextrin is a polysaccharide. It is derived from starch such as rice, corn, wheat, or potato starch.

In food, Maltodextrin is used to improve the texture and thicken a product. Due to its structure, it can help create a gel texture. As an emulsion stabilizer, it helps keep the ingredients in a product together.

As a polysaccharide, Maltodextrin has moisturizing properties. Polysaccharides are a type of carbohydrate. The top layer of skin uses polysaccharides to retain water, keeping the skin hydrated.

Maltodextrin is water soluble and has a sweet taste.

Learn more about Maltodextrin
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Skin Conditioning

Glycyrrhetinic acid is a compound found in licorice. It has skin conditioning, skin soothing, antibacterial, and antioxidant properties.

Not only is this a great ingredient for soothing inflammation, studies show this compound is effective at protecting skin against UV-B induced damage.

Fun fact: This ingredient is also used to mask the bitter taste of medicine.

Learn more about Glycyrrhetinic Acid

Sodium Polyacryloyldimethyl Taurate is a polymer and used to help stabilize other ingredients.

Emulsion stabilizers hold ingredients together, helping to create an even texture throughout the product.

Sodium Polyacryloyldimethyl Taurate can also be used to thicken the texture.

Learn more about Sodium Polyacryloyldimethyl Taurate
Emollient, Emulsifying, Skin Conditioning

Sucrose Dilaurate isn't fungal acne safe.

Emollient, Moisturising, Skin Conditioning

Jojoba Esters is a wax created from Jojoba oil. It is an emollient and film-forming ingredient. In bead form, it is an exfoliator.

This ingredient has high oxidative stability, meaning it doesn't break down when exposed to oxygen.

Its similarity to our skin's natural oils makes it a great emollient. Emollients help soften and soothe our skin by creating a barrier on top. This barrier helps trap moisture in, keeping skin hydrated.

It is created using either the hydrogenation or transesterification processes on jojoba oil.

Learn more about Jojoba Esters

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products. Due to its properties, it can prevent water and oil ingredients from separating.

Emollient, Emulsifying

Glyceryl Behenate is a fatty acid created from glycerin and behenic acid. It is an emollient and emulsifier.

This ingredient may not be Malassezia folliculitis, or fungal acne safe.

Emollient, Emulsifying

Glyceryl Stearate is a mix of glycerin and stearic acid.

It is used to stabilize the mixing of water and oil ingredients. By preventing these ingredients from separating, it can help elongate shelf life. It can also help thicken the product's texture.

As an emollient, it helps soften skin and supports barrier-replenishing ingredients.

In cosmetics, Glyceryl Stearate is often made from vegetable oils or synthetically produced.

This ingredient may not be fungal-acne safe

Fun fact: The human body also creates Glyceryl Stearate naturally.

Learn more about Glyceryl Stearate

Peg-100 Stearate is an emollient and emulsifier. As an emollient, it helps keep skin soft by trapping moisture in. On the other hand, emulsifiers help prevent oil and water from separating in a product.

PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.

We don't have a description for Helianthus Annuus Seed Cera yet.

Masking, Preservative

Benzoic Acid is used to preserve and adjust the pH of products.

The antimicrobial property of Benzoic Acid helps elongate a product's shelf life. Its main role is to reduce fungi growth and is not found to be effective at fighting bacteria. Therefore Benzoic Acid is always added along with other preservatives.

In its pure form, Benzoic Acid looks like a white crystalline solid. It has slight solubility in water.

The name of Benzoic Acid comes from gum benzoin, which used to be the sole source of deriving this ingredient. Benzoic Acid is the most simple aromatic carboxylic acid.

Benzoic Acid is naturally occuring in strawberries, mustard, cinnamon, and cloves. It has a slight scent but is not considered to be a fragrance.

Learn more about Benzoic Acid
Smoothing

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Learn more about Niacinamide
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum

Sodium Cocoyl Glutamate is a gentle cleanser and surfactant. It is the sodium salt of the Cocoyl Glutamic Acid and comes from coconut oil. As a surfactant, it helps lift dirt and oil to be washed away.

Sodium Cocoyl Glutamate also has an emolliating effect and can help leave the skin feeling soft.

Antioxidant, Skin Conditioning

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
Skin Conditioning, Skin Protecting

We don't have a description for Pisum Sativum Extract yet.

Emollient, Skin Conditioning, Skin Protecting

Acacia Decurrens Flower Cera isn't fungal acne safe.

Humectant

Polyglycerin-3 is a 3-unit glycerin polymer.

Like glycerin, this ingredient is a humectant. Humectants help hydrate your skin by drawing water to it.

Having moisturized skin helps improve the skin barrier. Your skin barrier helps protect against irritants and bacteria.

Learn more about Polyglycerin-3
Antioxidant, Masking, Skin Conditioning

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol

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· Updated May 6, 2025 Added by dariazaiets