Direia To The Stem Serum Ex Some
A serum that contains hyaluronic acid, peptides, vitamin c and vitamin e.
Overview
What it is
Serum with 44 ingredients that contains hyaluronic acid, peptides, Vitamin C and Vitamin E
Cool Features
It is reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, brightening skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates
Fun facts
Direia To is from Japan.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
About this product
Ingredients List
Dive into the full list of ingredients.
Water
Skin ConditioningButylene Glycol
HumectantGlycerin
HumectantHuman Embryonic Stem Cell Conditioned Media
HumectantHuman Adipose Derived Mesenchymal Cell Exosomes
Skin ConditioningS-Hiv-1 Oligopeptide-1
Sh-Oligopeptide-2
Skin ConditioningSh-Polypeptide-10
Skin ConditioningRh-Polypeptide-11
Skin ConditioningSh-Polypeptide-9
Skin ConditioningRh-Polypeptide-60
Skin ConditioningDefined Cell Culture Media 9
Skin ConditioningOligopeptide-24
Skin ConditioningOligopeptide-1
Skin ConditioningOligopeptide-13
Skin ProtectingOligopeptide-2
Skin ConditioningPlacental Extract
Palmitoyl Dipeptide-18
Capryloyl Dipeptide-17
EmollientAscorbic Acid
AntioxidantAscorbyl Propyl Hyaluronate
Skin ConditioningSodium Hyaluronate
HumectantArginine
MaskingOligopeptide-34
Skin ConditioningPhosphatidylcholine
EmulsifyingLecithin
EmollientCaprylic/Capric Glycerides
EmollientHydrogenated Lecithin
EmulsifyingCaprylyl Glycol
EmollientTetrasodium Etidronate
Emulsion StabilisingPentylene Glycol
Skin ConditioningLauryl Hydroxysultaine
CleansingTocopheryl Acetate
AntioxidantSodium Phosphate
BufferingPolysorbate 80
EmulsifyingCetyl Alcohol
EmollientGlycine Soja Oil
EmollientMyristyl Alcohol
EmollientDisodium EDTA
Sodium Hydroxide
BufferingSodium Oleate
CleansingCarbomer
Emulsion Stabilising1,2-Hexanediol
Skin ConditioningPhenoxyethanol
PreservativeWater, Butylene Glycol, Glycerin, Human Embryonic Stem Cell Conditioned Media, Human Adipose Derived Mesenchymal Cell Exosomes, S-Hiv-1 Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-10, Rh-Polypeptide-11, Sh-Polypeptide-9, Rh-Polypeptide-60, Defined Cell Culture Media 9, Oligopeptide-24, Oligopeptide-1, Oligopeptide-13, Oligopeptide-2, Placental Extract, Palmitoyl Dipeptide-18, Capryloyl Dipeptide-17, Ascorbic Acid, Ascorbyl Propyl Hyaluronate, Sodium Hyaluronate, Arginine, Oligopeptide-34, Phosphatidylcholine, Lecithin, Caprylic/Capric Glycerides, Hydrogenated Lecithin, Caprylyl Glycol, Tetrasodium Etidronate, Pentylene Glycol, Lauryl Hydroxysultaine, Tocopheryl Acetate, Sodium Phosphate, Polysorbate 80, Cetyl Alcohol, Glycine Soja Oil, Myristyl Alcohol, Disodium EDTA, Sodium Hydroxide, Sodium Oleate, Carbomer, 1,2-Hexanediol, Phenoxyethanol
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
- It has mild preservative properties.
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinWe don't have a description for Human Embryonic Stem Cell Conditioned Media yet.
We don't have a description for Human Adipose Derived Mesenchymal Cell Exosomes yet.
S-Hiv-1 Oligopeptide-1 is a peptide.
This peptide has similar properties to Sh-Oligopeptide-1.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
There is also controversy surrounding EGF. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Learn more about Sh-Oligopeptide-2Sh-Polypeptide-10 is a peptide.
Rh-Polypeptide-11 is a peptide.
Sh-Polypeptide-9 is a signal peptide that tells our body to create more blood vessels.
It is important to note, this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.
Rh-Polypeptide-60 is a peptide.
We don't have a description for Defined Cell Culture Media 9 yet.
Oligopeptide-24 is a peptide.
This synthetic peptide consists of glycine, histidine, and lysine. Peptides have skin conditioning properties.
This name refers to a group of Oligopeptide-1 derivatives, such as the famous Sh-Oligopeptide-1.
Oligopeptide-13 is a peptide.
We don't have a description for Placental Extract yet.
Palmitoyl Dipeptide-18 is a peptide.
Capryloyl Dipeptide-17 is a peptide.
Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.
Not only is vitamin C great for your overall health and immune system, it also has plenty of benefits on your skin.
Vitamin C is best used for brightening skin. It improves dark spots, acne scars, and hyperpigmentation. This is because it blocks the process of skin darkening when exposed to UV.
Remember: Vitamin C should not replace sunscreen!
Your skin uses vitamin C to build collagen. Collagen is one key component in having a strong skin barrier and plump skin. Vitamin C also plays a role in regulating collagen, thus making it effective in improving wrinkles and fine lines.
Ascorbic acid shows potent antioxidant activity. As an antioxidant, it helps fight free-radicals. Free-radicals are molecules that may damage your skin cells. These antioxidants also protect skin against UV damage.
The best formulations include Vitamin E and/or ferulic acid. These two ingredients help stabilize and provide a boost in the benefits of ascorbic acid. This is because ascorbic acid becomes unstable when exposed to UV and air. In fact, you can tell your ascorbic acid has oxidized when it turns an orange-yellow color.
Ascorbic acid is generally compatible with other ingredients. However, using ascorbic acid with other active ingredients might cause irritation. Two ingredients: copper ions and benzoyl peroxide, will inactivate ascorbic acid completely.
Read more about other types of Vitamin C:
Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.
Learn more about Ascorbic AcidAscorbyl Propyl Hyaluronate can help to reduce redness, improve skin texture, reduce the effects of aging, and brighten skin.
Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateArginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.
As a cosmetic ingredient, Arginine has antioxidant properties and can also help repair damaged skin. This ingredient is derived either synthetically or from animals.
Arginine isn't fungal acne safe when used in the presence of other lipids (fats, fatty acids, oils, esters, etc). Oils and fats occur naturally within the skin, so take caution when using Arginine if you're prone to fungal acne.
Learn more about ArginineOligopeptide-34 is a peptide.
Phosphatidylcholine is a type of phospholipid. Phospholipids are naturally found in our skin as they are the main component of cell membranes. Phospholipids are skin-replenishing.
This ingredient can be found in the Lecithin of soybeans.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.
This ingredient has emollient and emulsifying properties.
As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.
As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.
This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.
Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.
We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.
Learn more about LecithinCaprylic/capric glycerides are a mixture of fats from caprylic and capric acids.
As an emollient, Caprylic/Capric Glycerides helps soften and moisturize the skin. Emollients create a moisture-trapping film on the skin.
Emulsifiers prevent ingredients from separating.
Learn more about Caprylic/Capric GlyceridesHydrogenated Lecithin is created from the hydrogenation of lecithin (a group of phospholipids). Hydrogenation is a chemical reaction between hydrogen and another element.
This ingredient is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.
Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.
This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.
Learn more about Caprylyl GlycolWe don't have a description for Tetrasodium Etidronate yet.
Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolWe don't have a description for Lauryl Hydroxysultaine yet.
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateWe don't have a description for Sodium Phosphate yet.
Polysorbate 80 is a surfactant and emulsifier. It is used to keep ingredients together, and prevent oils and waters from separating.
It is made from polyethoxylated sorbitan and oleic acid. This ingredient can be found in cosmetics, foods, and medicine. It is water-soluble.
Polysorbate 80 may not be fungal acne safe.
Learn more about Polysorbate 80Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
Its main roles are:
Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol. The FDA allows products labeled "alcohol-free" to have fatty alcohols.
Learn more about Cetyl AlcoholGlycine Soja Oil comes from the soybean. Glycine Soja is native to eastern Asia.
Soybean oil is an emollient. It is rich in antioxidants and fatty acids including palmitic, stearic, oleic, and linoleic acids.
As an emollient, the fatty acids in soybean oil helps keep your skin soft and hydrated. It does so by creating a film on top that traps moisture in.
Soybean oil is also rich in vitamin E, a potent antioxidant. Vitamin E is also anti-inflammatory and provides a soothing effect.
Studies show soy may help fade hyperpigmentation from UVB. It does so by disrupting the melanin process from UVB induced skin inflammation.
This ingredient may not be malassezia folliculitis, or fungal-acne, safe.
Soybeans are rich in proteins and are part of the legume family. Foods made with soybeans include tofu, soymilk, edamame, miso, and soy sauce.
Learn more about Glycine Soja OilMyristyl Alcohol is type of fatty alcohol. It is a white, waxy solid and insoluble in water.
As an emollient, it hydrates the skin by trapping moisture in.
Fatty Alcohols are most often used as an emollient or to thicken a product. They are usually derived from natural fats and oils and therefore do not have the same drying or irritating effect as solvent alcohols.
Learn more about Myristyl AlcoholDisodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTASodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideWe don't have a description for Sodium Oleate yet.
Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.
A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
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Where it's from
Direia To is a Japanese brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated March 18, 2025 • Added by natalliabialevich