Paula's Choice Clinical Niacinamide 20% Treatment Versus Medik8 Liquid Peptides
Updated on June 28, 2024
Overview
What they are
These products are both cruelty-free and reef safe . They have a total of 7 ingredients in common
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and better texture
Free From
They both do not contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Paula's Choice Clinical Niacinamide 20% Treatment 25 ingredients
Medik8 Liquid Peptides 33 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
Paula's Choice Clinical Niacinamide 20% Treatment 25 ingredients
Medik8 Liquid Peptides 33 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningNiacinamide
Smoothing
Pentylene Glycol
Skin ConditioningButylene Glycol
Humectant
Glycerin
Humectant
Acetyl Glucosamine
Skin ConditioningAscorbyl Glucoside
Antioxidant
Glycyrrhiza Glabra Root Extract
Bleaching
Spiraea Ulmaria Extract
AstringentPortulaca Oleracea Extract
Skin ConditioningCamellia Japonica Flower Extract
EmollientEpigallocatechin Gallate
Antioxidant
Boerhavia Diffusa Root Extract
Skin Protecting
Camellia Sinensis Leaf Extract
Antimicrobial
Allantoin
Skin Conditioning
Lecithin
EmollientPullulan
Panthenol
Skin Conditioning
Silica
Abrasive
Xanthan Gum
EmulsifyingSclerotium Gum
Emulsion StabilisingPropanediol
SolventSodium Phytate
Phenoxyethanol
Preservative
Ethylhexylglycerin
Skin ConditioningWater, Niacinamide, Pentylene Glycol, Butylene Glycol, Glycerin, Acetyl Glucosamine, Ascorbyl Glucoside, Glycyrrhiza Glabra Root Extract, Spiraea Ulmaria Extract, Portulaca Oleracea Extract, Camellia Japonica Flower Extract, Epigallocatechin Gallate, Boerhavia Diffusa Root Extract, Camellia Sinensis Leaf Extract, Allantoin, Lecithin, Pullulan, Panthenol, Silica, Xanthan Gum, Sclerotium Gum, Propanediol, Sodium Phytate, Phenoxyethanol, Ethylhexylglycerin
Water
Skin ConditioningGlycerin
Humectant
Butylene Glycol
Humectant
Inulin
Skin ConditioningSodium Hyaluronate
Humectant
Panthenol
Skin Conditioning
Alpha-Glucan Oligosaccharide
CleansingCarnosine
Skin ConditioningCarbomer
Emulsion StabilisingPolysorbate 20
Emulsifying
Caprylyl Glycol
EmollientPhenoxyethanol
Preservative
Hydroxypropyl Cyclodextrin
MaskingDunaliella Salina Extract
Skin ConditioningEthylhexylglycerin
Skin ConditioningCitric Acid
Buffering
Palmitoyl Tripeptide-5
Skin Conditioning
Sodium Benzoate
Masking
Acetyl Hexapeptide-8
Humectant
Tetrapeptide-21
Skin Conditioning
Pentapeptide-18
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Pantolactone
HumectantPalmitoyl Tripeptide-38
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Glyceryl Caprylate
EmollientLactic Acid/Glycolic Acid Copolymer
Skin ConditioningPolyvinyl Alcohol
Phenylpropanol
Masking
Copper Palmitoyl Heptapeptide-14
Skin Conditioning
Heptapeptide-15 Palmitate
Skin Conditioning
Potassium Sorbate
Preservative
Xanthan Gum
EmulsifyingWater, Glycerin, Butylene Glycol, Inulin, Sodium Hyaluronate, Panthenol, Alpha-Glucan Oligosaccharide, Carnosine, Carbomer, Polysorbate 20, Caprylyl Glycol, Phenoxyethanol, Hydroxypropyl Cyclodextrin, Dunaliella Salina Extract, Ethylhexylglycerin, Citric Acid, Palmitoyl Tripeptide-5, Sodium Benzoate, Acetyl Hexapeptide-8, Tetrapeptide-21, Pentapeptide-18, Palmitoyl Tripeptide-1, Pantolactone, Palmitoyl Tripeptide-38, Palmitoyl Tetrapeptide-7, Glyceryl Caprylate, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Phenylpropanol, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Potassium Sorbate, Xanthan Gum
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
- It has mild preservative properties.
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Ingredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Paula's Choice Clinical Niacinamide 20% Treatment 25 ingredients
Medik8 Liquid Peptides 33 ingredients
Reviews
Here's what our community thinks
Paula's Choice Clinical Niacinamide 20% Treatment 25 ingredients
I wanted to find a niacinamide product that had other benefits like antioxidants. This caused huge cystic acne and flared up my FA. I suspect it's due to the lecithin which I found is not FA safe and in higher concentrations is problematic for acne prone skin.
Lecithin is a mixture of diglycerides of stearic, palmitic, and oleic acids. It can contain soybean oil and phospholipid fatty acids Show more
Good product :) My pores shrank and actually made a difference compared to 15 and 10 percent concentrations. I was surprised there was no irritation even after using twice a day. My skin loves niacinamide.
Medik8 Liquid Peptides 33 ingredients
I love this product. It has become a staple in my routine. It's such a shame they increased the price, but I rotate between this one and the ordinary multipeptide with copper. It's the perfect consistency and it does not get sticky, but it needs to be applied scarcely (around 4 drops). My skin loves this serum and it makes the skin hydrated without creating any excess oil. It does not trigger any Show more
It’s water based and firms my skin. My skin loves it. I also like Bare Minerals Herb Serum as it has niacinamide and my skin loves that too. Medik8 Crystal Retinal 3 and 6 also. Elemis pro rad cream wash and dynamic resurf and kefir mist
