This anti-aging serum is formulated around Adenosine to soften the look of wrinkles.
This anti-aging ampoule is formulated around Acetyl Hexapeptide-8 and Palmitoyl Pentapeptide-4 to soften the look of wrinkles.
What's inside
What's inside
Key Ingredients
No key ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Skin ConditioningDipropylene Glycol
HumectantGlycerin
Humectant
Caprylic/Capric Triglyceride
Masking
Hydrogenated Poly(C6-14 Olefin)
EmollientHydrogenated Polydecene
EmollientPolyglyceryl-3 Methylglucose Distearate
Emulsifying
Limnanthes Alba Seed Oil
Skin Conditioning
Pentylene Glycol
Skin Conditioning
Cetearyl Alcohol
Emollient
Glyceryl Stearate
Emollient
Hydrogenated Vegetable Oil
Emollient
Jojoba Esters
Emollient
Behenyl Alcohol
Emollient
1,2-Hexanediol
Skin Conditioning
Dipentaerythrityl Hexahydroxystearate/Hexastearate/Hexarosinate
Skin ConditioningPolymethylsilsesquioxane
Cetearyl Olivate
Sorbitan Olivate
Emulsifying
Hydrogenated Lecithin
Emulsifying
Methyl Trimethicone
Skin Conditioning
Hydroxyacetophenone
Antioxidant
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingBehenic Acid
Cleansing
Carbomer
Emulsion StabilisingTromethamine
BufferingStearic Acid
Cleansing
Stearyl Alcohol
Emollient
Xanthan Gum
EmulsifyingAdenosine
Skin Conditioning
Citrus Aurantium Bergamia Fruit Oil
Masking
Pelargonium Graveolens Flower Oil
Masking
Hydrolyzed Collagen
Emollient
Melia Azadirachta Flower Extract
Skin ConditioningMyristic Acid
Cleansing
Sodium Phytate
ChelatingMelia Azadirachta Leaf Extract
Skin ConditioningCurcuma Longa Root Extract
Antioxidant
Ocimum Sanctum Leaf Extract
Skin ConditioningDextrin
AbsorbentTheobroma Cacao Seed Extract
Antioxidant
Corallina Officinalis Extract
Skin Conditioning
Tocopherol
Antioxidant
Butylene Glycol
Humectant
Caprylyl Glycol
Emollient
Ethylhexylglycerin
Skin ConditioningOligopeptide-1
Skin Conditioning
Acetyl Hexapeptide-8
Humectant
Palmitoyl Pentapeptide-4
Skin Conditioning
Water, Dipropylene Glycol, Glycerin, Caprylic/Capric Triglyceride, Hydrogenated Poly(C6-14 Olefin), Hydrogenated Polydecene, Polyglyceryl-3 Methylglucose Distearate, Limnanthes Alba Seed Oil, Pentylene Glycol, Cetearyl Alcohol, Glyceryl Stearate, Hydrogenated Vegetable Oil, Jojoba Esters, Behenyl Alcohol, 1,2-Hexanediol, Dipentaerythrityl Hexahydroxystearate/Hexastearate/Hexarosinate, Polymethylsilsesquioxane, Cetearyl Olivate, Sorbitan Olivate, Hydrogenated Lecithin, Methyl Trimethicone, Hydroxyacetophenone, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Behenic Acid, Carbomer, Tromethamine, Stearic Acid, Stearyl Alcohol, Xanthan Gum, Adenosine, Citrus Aurantium Bergamia Fruit Oil, Pelargonium Graveolens Flower Oil, Hydrolyzed Collagen, Melia Azadirachta Flower Extract, Myristic Acid, Sodium Phytate, Melia Azadirachta Leaf Extract, Curcuma Longa Root Extract, Ocimum Sanctum Leaf Extract, Dextrin, Theobroma Cacao Seed Extract, Corallina Officinalis Extract, Tocopherol, Butylene Glycol, Caprylyl Glycol, Ethylhexylglycerin, Oligopeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Learn more about AdenosineCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolCarbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Learn more about CarbomerEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinHydrolyzed Collagen is Collagen (usually sourced from fish, bovine, or porcine byproducts) that's been broken down into smaller peptides. This makes it water-soluble and easy to blend into formulations.
In a formula, it works mainly as a skin-conditioning and moisturizing agent.
The small peptides and amino acids (including Natural Moisturizing Factor components like Hydroxyproline, Serine, and Aspartic Acid) help the surface of the skin hold onto water, feel softer, and look temporarily plumper.
This ingredient also has mild film-forming and antioxidant properties with research showing the antioxidant effect is stronger the lower the molecular weight of the peptides.
It's worth being realistic here:
Topically applied Hydrolyzed Collagen conditions the upper layers of skin rather than rebuilding the structural collagen deep in your dermis (the wrinkle-and-firmness benefits people associate with Collagen mostly come from oral supplements in studies, not topicals).
However, recent lab and skin-model work on Hydrolyzed Fish Collagen has shown promising effects on cell viability and wound healing when used as an active.
Typical concentrations range from 0.2-2%, but the percentage can go much higher in rinse-off or hair products (sometimes even above 50%).
Clinical studies on this ingredient showed no irritation, sensitization, or phototoxicity.
If you are looking for vegan collagen, it usually goes by a different INCI name like hydrolyzed soy protein. Vegan collagen is derived from yeast, bacteria, or plant sources.
The results are varied.
A study from 2021 found hydrolyzed collagen increased elasticity and improved wrinkles in 1,125 participants between age 20 and 70. Another study found increased skin thickness in participants between the ages of 45 to 59.
However, It is difficult to prove that oral collagen will end up working on your skin. Many of the studies using hydrolyzed collagen also add several vitamins and nutrients into the test mixture as well.
Further studies are needed at this time.
Learn more about Hydrolyzed Collagen
