Eudora Sérum Preenchedor Neo Dermo Active Pro Collection Versus ISDIN Isdinceutics Hyaluronic Concentrate
This hydrating serum is formulated around Panthenol and Sodium Hyaluronate to hydrate skin and soften the look of wrinkles.
This hydrating serum is formulated around Pseudoalteromonas Ferment Extract and Hydrolyzed Hyaluronic Acid to hydrate skin and soften the look of wrinkles.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningPropanediol
SolventPEG-40 Hydrogenated Castor Oil
EmulsifyingDimethicone
EmollientPanthenol
Skin ConditioningSodium Hyaluronate
HumectantPhenoxyethanol
PreservativeHydroxyacetophenone
AntioxidantSodium Acrylates Copolymer
Hydrolyzed Hyaluronic Acid
HumectantParfum
MaskingDimethiconol
EmollientLecithin
EmollientDimethicone Crosspolymer
Emulsion StabilisingDisodium EDTA
Biosaccharide Gum-1
HumectantTriethanolamine
BufferingCitric Acid
BufferingGlycerin
HumectantCalanthe Discolor Extract
Skin ConditioningXanthan Gum
EmulsifyingSodium Benzoate
MaskingGluconolactone
Skin ConditioningCalcium Gluconate
HumectantBenzyl Salicylate
PerfumingCitronellol
PerfumingGeraniol
PerfumingHydroxycitronellal
PerfumingLinalool
PerfumingWater, Propanediol, PEG-40 Hydrogenated Castor Oil, Dimethicone, Panthenol, Sodium Hyaluronate, Phenoxyethanol, Hydroxyacetophenone, Sodium Acrylates Copolymer, Hydrolyzed Hyaluronic Acid, Parfum, Dimethiconol, Lecithin, Dimethicone Crosspolymer, Disodium EDTA, Biosaccharide Gum-1, Triethanolamine, Citric Acid, Glycerin, Calanthe Discolor Extract, Xanthan Gum, Sodium Benzoate, Gluconolactone, Calcium Gluconate, Benzyl Salicylate, Citronellol, Geraniol, Hydroxycitronellal, Linalool
Water
Skin ConditioningDimethicone
EmollientPropanediol
SolventGlycerin
Humectant1,2-Hexanediol
Skin ConditioningSodium Acrylates Copolymer
Dimethicone Crosspolymer
Emulsion StabilisingButylene Glycol
HumectantPseudoalteromonas Ferment Extract
HumectantGlycereth-26
HumectantLecithin
EmollientMaltodextrin
AbsorbentSodium Benzoate
MaskingPentylene Glycol
Skin ConditioningLens Esculenta Seed Extract
Skin ProtectingParfum
MaskingDisodium EDTA
Hydrolyzed Hyaluronic Acid
HumectantSodium Hyaluronate
HumectantXanthan Gum
EmulsifyingCitric Acid
BufferingBiosaccharide Gum-1
HumectantCarbomer
Emulsion StabilisingPolysorbate 20
EmulsifyingSodium Lactate
BufferingSodium Salicylate
PreservativeSalicylic Acid
MaskingPalmitoyl Tripeptide-1
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningWater, Dimethicone, Propanediol, Glycerin, 1,2-Hexanediol, Sodium Acrylates Copolymer, Dimethicone Crosspolymer, Butylene Glycol, Pseudoalteromonas Ferment Extract, Glycereth-26, Lecithin, Maltodextrin, Sodium Benzoate, Pentylene Glycol, Lens Esculenta Seed Extract, Parfum, Disodium EDTA, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Xanthan Gum, Citric Acid, Biosaccharide Gum-1, Carbomer, Polysorbate 20, Sodium Lactate, Sodium Salicylate, Salicylic Acid, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Biosaccharide Gum-1 is a sugar created by fermenting sorbitol (which usually comes from potato starch!). It is known for its soothing and moisturizing properties.
Manufacturer tests show this ingredient helped reduce irritation from lactic acid by almost half and kept skin hydrated long-term as a humectant
Beyond hydration, Biosaccharide Gum-1 gives formulas a silky, non-sticky feel.
This ingredient is gentle, versatile, and suitable for all skin types.
Fun fact: Similar sugars can be found naturally in fruits like apples and pears.
Learn more about Biosaccharide Gum-1Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.
Learn more about Citric AcidDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeDimethicone Crosspolymer is a silicone created by modifying dimethicone with hydrocarbon side chains. Due to its large size, it does not penetrate skin. It is considered non-occlusive.
Dimethicone Crosspolymer is used to stabilize and thicken products. It also helps give products a silky feel.
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinHydrolyzed Hyaluronic Acid is hyaluronic acid (HA) that is broken down into lower molecular weight fragments.
It's a humectant that pulls and holds water in the skin to help with hydration, plumpness, and reduce transepidermal water loss.
Because hydrolyzed hyaluronic acid is smaller in size, it can slip past your outermost layer of skin more easily than full-sized HA.
Most formulations will combine all sizes to get the best of both worlds.
Typical usage levels range from 0.01-1%. Any percentage higher than 2% might become goopy and tacky.
Learn more about Hydrolyzed Hyaluronic AcidLecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Learn more about LecithinParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumPropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolThis ingredient is a synthetic, salt form polymer built from acrylic acid, ethacrylic acid, or their simple esters. It works as a binder, film former, and viscosity increasing agent.
Typical concentrations start at around 0.5% but can go up to 25% for film-forming or binding.
The CIR Expert Panel assessed the safety of 126 acrylates copolymers and concluded they are safe in cosmetics at current use levels when formulated to be non-irritating. They also noted the levels present in finished cosmetic products are not considered a safety risk and Genotoxicity testing (Ames tests, chromosomal aberration assays) has come back negative across the board.
Though the raw building blocks (like acrylic acid) can be irritating on their own, cosmetic-grade versions go through purification to keep levels extremely low.
Sodium Acrylates Copolymer is a large molecule that doesn't penetrate skin barrier in any meaningful way.
Learn more about Sodium Acrylates CopolymerSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoateSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan Gum