Dr. Jart+ Pore Remedy PHA Exfoliating Serum Versus Dr. Jart+ Pore-Remedy Smoothing Primer

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

PHAs are more gentle than AHAs due to their larger structure. They do not penetrate as deeply as AHAs and take a longer time to dissolve dead cells. Studies show PHAs do not cause as much irritation.

Gluconolactone has some interesting properties:

In a 2004 study, Gluconolactone was found to prevent UV damage in mouse skin cells and has not been found to increase sun sensitivity. However, we still recommend wearing SPF daily.

This ingredient is is an created by reacting gluconic acid with an alcohol.

The glycoproteins found in skincare are most commonly derived from yeast, algae, or plant sources.

In-vitro studies have shown that yeast-derived glycoproteins can boost cellular oxygen content and increase energy production in skin cells.

In general, this is a well-tolerated humectant and skin conditioning ingredient. The Cosmetic Ingredient Review (CIR) Expert Panel has found no signs of irritation, adverse effects, or abnormal reactions from this ingredient.

At higher doses or for those with sensitive skin, methol-type cooling can quickly turn into burning/irritation. It can also trigger irritant dermatitis or even allergic contact dermatitis. In a large patch-test dataset, peppermint oil had a low but positive rate for this.

In cosmetics, Cosmetic Safety Reviews (CIR) concludes that peppermint oil is safe to use when formulated to be non-sensitizing with some restrictions; for instance, pulegone, a naturally occurring component of peppermint oil, should not exceed 1%.

Since peppermint oil contains fragrance allergens such as limonene, linalool, and menthol, it can be sensitizing for those with rosacea, eczema, a broken skin barrier, or just sensitive skin in general.

In Japan, this ingredient is known as Hakka Yu.

Lab studies show carvone to have antioxidant and antimicrobial activity, but it is a recognized fragrance allergen. Carvone is a mild skin sensitizer while limonene is a well-known one.

In a 21-year retrospective from a Swedish patch test clinic, 3.5% of patients tested positive for sensitive towards carvone.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!