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Dermelect Outcrease Retinol Trifecta Serum Versus Theramid Clinical Vitamin A

Serum
Serum
American Brand United States
Spanish Brand Spain

Updated on January 17, 2025

Overview

What they are

These products are both vegan, cruelty-free, and reef safe serums. They have a total of 3 ingredients in common

Cool Features

They both contain ceramides, retinoid and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, common allergens, oils, parabens or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

Free from

Safety & Ethics

American Brand

Brand country of origin

Free from

Safety & Ethics

pH Level 5.25

Product acidity level

Spanish Brand

Brand country of origin

At a glance

Click on any of the items below to learn more

Ingredients, at a glance

What's in this product, and how it might affect your skin.

Notable Ingredients

Benefits

Concerns

Ingredients, at a glance

What's in this product, and how it might affect your skin.

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Outcrease Retinol Trifecta Serum
Cyclopentasiloxane Emollient, Skin Conditioning, Solvent
Silicon Icon

Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.

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SiliconSilicon Icon
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Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0 Silicon Icon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration.

1 Com. / 0 Irr.
Very disliked
SiliconSilicon Icon
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Dimethiconol Emollient, Moisturising

Dimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.

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Vinyl Dimethicone/Lauryl Dimethicone Crosspolymer

We don't have a description for Vinyl Dimethicone/Lauryl Dimethicone Crosspolymer yet.

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Polysorbate 20 Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

0 Com. / 0 Irr.
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Retinol Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.

Loved by users
RetinoidRetinoid Icon8 BenefitsMay worsen RosaceaMay worsen Rosacea Icon
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PEG-8 Humectant, Solvent

PEG-8 is a synthetic polymer used as a humectant and solvent.

Very disliked
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Tocopherol Antioxidant, Masking, Skin Conditioning
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

0-3 Com. / 0-3 Irr.
Liked by users
Vitamin EVitamin E IconAntioxidantAntioxidant Icon3 Benefits
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Ascorbyl Palmitate Antioxidant, Masking
2 / 0 Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconNot safe for Fungal Acne Icon

Ascorbyl Palmitate is created by combining pure Vitamin C and palmitic acid. It is an antioxidant and helps reduce hyperpigmentation.

2 Com. / 0 Irr.
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Vitamin CVitamin C IconAntioxidantAntioxidant Icon6 BenefitsNot safe for Fungal AcneNot safe for Fungal Acne Icon
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Ascorbic Acid Antioxidant, Buffering, Masking
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon

Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.

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Vitamin CVitamin C IconAntioxidantAntioxidant Icon7 Benefits
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Citric Acid Buffering, Masking
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

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AHAAHA Icon5 BenefitsMay worsen RosaceaMay worsen Rosacea Icon
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Retinyl Palmitate Skin Conditioning
1-3 / 1-3 Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconNot safe for Fungal Acne IconMay worsen Rosacea Icon

Retinyl palmitate is a form of retinoid. Retinoids are the superstar class of anti-aging ingredients that include tretinoin and retinol.

1-3 Com. / 1-3 Irr.
Mixed reviews
RetinoidRetinoid Icon8 Benefits2 Concerns
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Retinyl Acetate Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Retinyl Acetate is a form of retinoid. It can be good for be good for oily skin. It can help to improve skin texture, reduce large pores, reduce the effects of aging, reduce the visibility of dark spots, heal scars, brighten skin, and fight acne.

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RetinoidRetinoid Icon8 Benefits
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C12-15 Alkyl Benzoate Antimicrobial, Emollient, Skin Conditioning

C12-15 Alkyl Benzoate is made up of Benzoic Acid and long chain alcohols. It has a low molecular weight.

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Tribehenin Emollient, Skin Conditioning
0 / 0 Not safe for Fungal Acne Icon

Tribehenin comes from glycerin and behenic acid.

0 Com. / 0 Irr.
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Ceramide 2 Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide 2 is a type of Ceramide. This ingredient was retired in 2014, please see Ceramide NG instead.

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CeramideCeramide Icon3 Benefits
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PEG-10 Humectant, Solvent

We don't have a description for PEG-10 yet.

Not enough ratings
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PEG-5 Rapeseed Sterol Cleansing, Emulsifying
Not safe for Fungal Acne Icon

PEG-5 Rapeseed Sterol isn't fungal acne safe.

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Palmitoyl Oligopeptide Cleansing, Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Palmitoyl Oligopeptide is a form of peptide. It is created by blending peptides with palmitic acid. Peptides are building blocks for protein.

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PeptidePeptide IconNot safe for Fungal AcneNot safe for Fungal Acne Icon
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Clinical Vitamin A
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

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Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
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2 Benefits
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Coco-Caprylate/Caprate Emollient, Skin Conditioning
Not safe for Fungal Acne Icon

Coco-Caprylate/Caprate is created from fatty coconut alcohol, caprylic acid, and capric acid.

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Caprylic/Capric Triglyceride Masking, Skin Conditioning

Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

Mixed reviews
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Propanediol Solvent

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

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Coco-Caprylate Emollient
Not safe for Fungal Acne Icon

Coco-Caprylate is created from fatty coconut alcohol and caprylic acid.

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Dimethyl Isosorbide Solvent

Dimethyl Isosorbide is a solvent and helps deliver actives into your skin. It is created from sorbitol.

Mixed reviews
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Polyglyceryl-6 Distearate Emulsifying
Not safe for Fungal Acne Icon

Polyglyceryl-6 Distearate isn't fungal acne safe.

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Cellulose Acetate Butyrate

We don't have a description for Cellulose Acetate Butyrate yet.

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Cetyl Alcohol Emollient, Emulsifying, Emulsion Stabilising
2 / 2 Fatty Alcohol Icon

Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.

2 Com. / 2 Irr.
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Fatty AlcoholFatty Alcohol Icon
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Hydroxypinacolone Retinoate Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

This ingredient is a retinoid. It usually goes by a more common name: "Granactive".

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RetinoidRetinoid Icon8 Benefits
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Retinol Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.

Loved by users
RetinoidRetinoid Icon8 BenefitsMay worsen RosaceaMay worsen Rosacea Icon
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Retinal Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Retinal is a form of retinoid. Retinoids are the gold-standard class of anti-aging ingredients.

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RetinoidRetinoid Icon8 BenefitsMay worsen RosaceaMay worsen Rosacea Icon
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Lactococcus Ferment Lysate Skin Conditioning

Lactococcus Ferment Lysate is a postbiotic created by fermenting Lactoccus lactis, a type of bacteria more commonly used to create Lactic acid.

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Plankton Extract Skin Conditioning

We don't have a description for Plankton Extract yet.

Mixed reviews
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Ceramide Ng Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide NG is a type of Ceramide. The NG stands for a sphinganine base.

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CeramideCeramide Icon3 Benefits
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Tocopherol Antioxidant, Masking, Skin Conditioning
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

0-3 Com. / 0-3 Irr.
Liked by users
Vitamin EVitamin E IconAntioxidantAntioxidant Icon3 Benefits
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Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Mixed reviews
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Jojoba Esters Emollient, Moisturising, Skin Conditioning
Not safe for Fungal Acne Icon

Jojoba Esters is a wax created from Jojoba oil. It is an emollient and film-forming ingredient. In bead form, it is an exfoliator.

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Lecithin Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids.

Mixed reviews
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Pullulan

Pullulan is a low viscosity polysaccharide (a long chain carbohydrate) with binding and film forming properties when dissolved in water. It is used to create a "silicone-like" or silky feel in cosmetics without adding viscosity.

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Sclerotium Gum Emulsion Stabilising, Skin Conditioning

Sclerotium Gum is a polysaccharide gum made by the fungus, Sclerotium rolfssii. It is similar to xanthan gum.

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Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

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Tricaprylin Masking, Perfuming, Skin Conditioning
Fragrance Icon

Tricaprylin is a fragrance.

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FragranceFragrance Icon
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Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Antioxidant
Antioxidant Icon

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate (long name, huh?) is a synthetic antioxidant.

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AntioxidantAntioxidant Icon
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Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

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Silica Abrasive, Absorbent
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon

Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.

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ExfoliantExfoliant Icon2 Concerns
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Sodium Chloride Masking
Can worsen Dry Skin IconBad for Acne Prone Skin IconMay worsen Rosacea Icon

Chances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt.

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3 Concerns
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Lactic Acid Buffering, Humectant, Skin Conditioning
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Lactic Acid is an AHA that is derived from fermenting lactose, a carbohydrate from milk. It removes the top layer of old and dead skin cells and helps increase cell turnover.

Loved by users
AHAAHA Icon7 Benefits2 Concerns
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Citric Acid Buffering, Masking
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

Disliked by users
AHAAHA Icon5 BenefitsMay worsen RosaceaMay worsen Rosacea Icon
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Phenoxyethanol Preservative
Preservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

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PreservativePreservative Icon
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Sodium Benzoate Masking, Preservative
Preservative Icon

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

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Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning
Loved

Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.

Why is retinol famous?

It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.

Retinol is proven to:

This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.

Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).

Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

We recommend speaking with a medical professional about using this ingredient during pregnancy.

Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.

Read about Tretinoin

Learn more about Retinol
Antioxidant, Masking, Skin Conditioning
Liked

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol
Buffering, Masking
Disliked

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.

If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.

Read more about some other popular AHA's here:

Learn more about Citric Acid

When to use

12 Routines
42% use in am
58% use in pm
100% use every day
20 Routines
5% use in am
90% use in pm
35% use every day