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DRMTLGY Retinol Complex 0.5% Versus Dermelect Outcrease Retinol Trifecta Serum

Serum
Serum
American Brand United States
American Brand United States

Updated on January 17, 2025

Overview

What they are

These products are both cruelty-free and reef safe serums. They have a total of 4 ingredients in common

Cool Features

They both contain retinoid, Vitamin C and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates

What's Inside

They both contain silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

Free from

Safety & Ethics

American Brand

Brand country of origin

Free from

Safety & Ethics

American Brand

Brand country of origin

At a glance

Click on any of the items below to learn more

Ingredients, at a glance

What's in this product, and how it might affect your skin.

Notable Ingredients

Benefits

Concerns

Ingredients, at a glance

What's in this product, and how it might affect your skin.

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Retinol Complex 0.5%
Cyclopentasiloxane Emollient, Skin Conditioning, Solvent
Silicon Icon

Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.

Disliked by users
SiliconSilicon Icon
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Dimethicone Crosspolymer Emulsion Stabilising

Dimethicone Crosspolymer is a silicone created by modifying dimethicone with hydrocarbon side chains. Due to its large size, it does not penetrate skin. It is considered non-occlusive.

Very disliked
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Dimethicone/Vinyl Dimethicone Crosspolymer Skin Conditioning

This ingredient is a silicone used to improve the texture of products and absorb oil. It does not get absorbed into the skin.

Very disliked
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Dimethiconol Emollient, Moisturising

Dimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.

Very disliked
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Caprylic/Capric Triglyceride Masking, Skin Conditioning

Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

Mixed reviews
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Sodium Ascorbate Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Sodium Ascorbate is a form of Vitamin C. It is derived from the sodium salt of ascorbic acid.

Liked by users
Vitamin CVitamin C IconAntioxidantAntioxidant Icon4 Benefits
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Tocopherol Antioxidant, Masking, Skin Conditioning
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

0-3 Com. / 0-3 Irr.
Liked by users
Vitamin EVitamin E IconAntioxidantAntioxidant Icon3 Benefits
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Retinol Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.

Loved by users
RetinoidRetinoid Icon8 BenefitsMay worsen RosaceaMay worsen Rosacea Icon
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Outcrease Retinol Trifecta Serum
Cyclopentasiloxane Emollient, Skin Conditioning, Solvent
Silicon Icon

Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.

Disliked by users
SiliconSilicon Icon
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Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0 Silicon Icon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration.

1 Com. / 0 Irr.
Very disliked
SiliconSilicon Icon
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Dimethiconol Emollient, Moisturising

Dimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.

Very disliked
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Vinyl Dimethicone/Lauryl Dimethicone Crosspolymer

We don't have a description for Vinyl Dimethicone/Lauryl Dimethicone Crosspolymer yet.

Not enough ratings
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Polysorbate 20 Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

0 Com. / 0 Irr.
Very disliked
Not safe for Fungal AcneNot safe for Fungal Acne Icon
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Retinol Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.

Loved by users
RetinoidRetinoid Icon8 BenefitsMay worsen RosaceaMay worsen Rosacea Icon
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PEG-8 Humectant, Solvent

PEG-8 is a synthetic polymer used as a humectant and solvent.

Very disliked
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Tocopherol Antioxidant, Masking, Skin Conditioning
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

0-3 Com. / 0-3 Irr.
Liked by users
Vitamin EVitamin E IconAntioxidantAntioxidant Icon3 Benefits
Learn more
Ascorbyl Palmitate Antioxidant, Masking
2 / 0 Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconNot safe for Fungal Acne Icon

Ascorbyl Palmitate is created by combining pure Vitamin C and palmitic acid. It is an antioxidant and helps reduce hyperpigmentation.

2 Com. / 0 Irr.
Disliked by users
Vitamin CVitamin C IconAntioxidantAntioxidant Icon6 BenefitsNot safe for Fungal AcneNot safe for Fungal Acne Icon
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Ascorbic Acid Antioxidant, Buffering, Masking
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon

Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.

Loved by users
Vitamin CVitamin C IconAntioxidantAntioxidant Icon7 Benefits
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Citric Acid Buffering, Masking
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

Disliked by users
AHAAHA Icon5 BenefitsMay worsen RosaceaMay worsen Rosacea Icon
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Retinyl Palmitate Skin Conditioning
1-3 / 1-3 Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconNot safe for Fungal Acne IconMay worsen Rosacea Icon

Retinyl palmitate is a form of retinoid. Retinoids are the superstar class of anti-aging ingredients that include tretinoin and retinol.

1-3 Com. / 1-3 Irr.
Mixed reviews
RetinoidRetinoid Icon8 Benefits2 Concerns
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Retinyl Acetate Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Retinyl Acetate is a form of retinoid. It can be good for be good for oily skin. It can help to improve skin texture, reduce large pores, reduce the effects of aging, reduce the visibility of dark spots, heal scars, brighten skin, and fight acne.

Liked by users
RetinoidRetinoid Icon8 Benefits
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C12-15 Alkyl Benzoate Antimicrobial, Emollient, Skin Conditioning

C12-15 Alkyl Benzoate is made up of Benzoic Acid and long chain alcohols. It has a low molecular weight.

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Tribehenin Emollient, Skin Conditioning
0 / 0 Not safe for Fungal Acne Icon

Tribehenin comes from glycerin and behenic acid.

0 Com. / 0 Irr.
Disliked by users
Not safe for Fungal AcneNot safe for Fungal Acne Icon
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Ceramide 2 Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide 2 is a type of Ceramide. This ingredient was retired in 2014, please see Ceramide NG instead.

Loved by users
CeramideCeramide Icon3 Benefits
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PEG-10 Humectant, Solvent

We don't have a description for PEG-10 yet.

Not enough ratings
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PEG-5 Rapeseed Sterol Cleansing, Emulsifying
Not safe for Fungal Acne Icon

PEG-5 Rapeseed Sterol isn't fungal acne safe.

Not enough ratings
Not safe for Fungal AcneNot safe for Fungal Acne Icon
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Palmitoyl Oligopeptide Cleansing, Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Palmitoyl Oligopeptide is a form of peptide. It is created by blending peptides with palmitic acid. Peptides are building blocks for protein.

Liked by users
PeptidePeptide IconNot safe for Fungal AcneNot safe for Fungal Acne Icon
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Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Emollient, Skin Conditioning, Solvent
Disliked

Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.

D5 is considered lightweight and volatile. Volatile means it evaporates quickly after application. Once evaporated, D5 leaves a thin barrier that helps keep skin hydrated.

D5 is an emollient. Emollients help soften the skin and prevent water loss. Silicones create a silky texture in products. D5 helps other ingredients become more spreadable.

Studies show D5 is safe to use in skincare products. We recommend speaking with a skincare professional if you have concerns.

Learn more about Cyclopentasiloxane
Emollient, Moisturising
Very Disliked

Dimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.

This ingredient helps to create a silky texture and improve spreadability. Due to its high molecular weight and thickness, it is often combined with cyclopentasiloxane.

Antioxidant, Masking, Skin Conditioning
Liked

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol
Skin Conditioning
Loved

Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.

Why is retinol famous?

It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.

Retinol is proven to:

This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.

Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).

Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

We recommend speaking with a medical professional about using this ingredient during pregnancy.

Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.

Read about Tretinoin

Learn more about Retinol

When to use

21 Routines
10% use in am
90% use in pm
86% use every day
12 Routines
42% use in am
58% use in pm
100% use every day