Versus

Biretix Tri-Active Anti-Blemish Gel Versus La Roche-Posay Effaclar Duo+ Global Acne Treatment

Facial Treatment
Facial Treatment
Spanish Brand Spain
French Brand France

Updated on February 18, 2025

Overview

What they are

These products are both reef safe facial treatments. They have a total of 3 ingredients in common

Cool Features

They both contain niacinamide

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any common allergens, oils, parabens or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Effaclar Duo+ Global Acne Treatment

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Smoothing

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Learn more about Niacinamide
Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol

When to use

35 Routines
17% use in am
83% use in pm
57% use every day
When to use See routines that use it ->
277 Routines
44% use in am
56% use in pm
86% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Biretix Tri-Active Anti-Blemish Gel 26 ingredients

5.0 /5
from 1 rating
SpyrothLasagiades's avatar

SpyrothLasagiades

1 year ago
Review

Strongone
Strong enough for acne and wrinkles.
15% glycolic acid, 2% salicylic acid, 5% niacinamide, retinol! But.... unsafe for fungal acne due to polysorbate 20.

La Roche-Posay Effaclar Duo+ Global Acne Treatment 29 ingredients

4.0 /5
from 2 ratings
YousifShamoon's avatar

YousifShamoon

2 years ago
Review

interesting to say the least
no one warned me about the purge i was gonna get from this. the crease on my nose and my chin turned red and were peeling for weeks but i think it paid off in the end. it handled my sebum production and pimples very well, but unfortunately i can't say the same for my blackheads and whiteheads, which remained unbothered by this product. another thing i wasn't warned Show more