Regis Designline Triple Effect Leave-In Conditioner

Regis Designline Triple Effect Leave-In Conditioner

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Overview

What it is

Leave-in conditioner with 25 ingredients that contains AHA and exfoliants

Cool Features

It is reef safe

Suited For

It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

It doesn't contain any parabens or sulfates

Fun facts

Regis is from United States.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Explained

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Learn more about Water
Emollient, Emulsifying, Emulsion Stabilising

Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.

Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.

It plays several roles in a formula:

Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.

Multiple assessments have found it to be non-irritating and non-sensitizing to most people.

However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.

Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.

Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.

Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.

This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.

Learn more about Cetearyl Alcohol
Emollient, Skin Conditioning, Solvent

Cyclopentasiloxane, or D5, is a silicone used to improve texture of products and trap moisture.

D5 is considered lightweight and volatile. Volatile means it evaporates quickly after application. Once evaporated, D5 leaves a thin barrier that helps keep skin hydrated.

It is also an emollient. Emollients help soften the skin and prevent water loss. Silicones create a silky texture in products. D5 helps other ingredients become more spreadable.

Studies show D5 is safe to use in skincare products. We recommend speaking with a skincare professional if you have concerns.

Learn more about Cyclopentasiloxane

We don't have a description for Quaternium-80 yet.

This water-soluble silicone is used for its hydrating and softening properties. It is used to add a silky feel to skincare products and has great benefits for haircare.

In haircare, this ingredient:

  • Adds shine
  • Protects color
  • Offers thermal protection
  • Boosts hair strength
  • Does not build up as easily
Emollient, Skin Conditioning

You may know this ingredient as argan oil. It has emollient and skin conditioning properties that help soften skin and reinforce the lipid barrier.

The fatty acid profile of argan oil is roughly 45-55% oleic acid, 28-36% linoleic acid, 10-15% palmitic acid, and 5-7% stearic acid. It also contains vitamin E, sterols, squalene, and polyphenols like ferulic acid.

Two clinical studies in postmenopausal women found that applying argan oil for 60 days significantly improved skin elasticity and moisturization (reduced transepidermal water loss and increased epidermal water content).

Since it is high in oleic and linoleic acid, this ingredient may not be fungal acne safe. Both of these fall in the C11-C24 range that Malassezia yeast can metabolize.

Learn more about Argania Spinosa Kernel Oil
Skin Conditioning

Keratin is a protein naturally found in our hair and skin.

In haircare, it has been shown to seal broken cuticles. This can help prevent breakage and split ends.

Humectant, Skin Conditioning

Hydrolyzed Keratin is derived from keratin. Keratin is a large protein that is naturally found in our hair and skin.

Studies show keratin is able to seal broken hair cuticles, helping to prevent split ends and breakage.

As a humectant, hydrolyzed keratin helps draw moisture from the air to your hair and skin. This helps keep your skin and hair hydrated.

Learn more about Hydrolyzed Keratin
Skin Conditioning

We don't have a description for Oxidized Keratin yet.

Skin Conditioning

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Learn more about Panthenol

This ingredient is a preservative and often used for it's anti-static properties. You'll most likely see this ingredient in hair conditioners.

It does not cause irritation or sensitization in leave-on products at 1-5%.

Antimicrobial, Emulsifying, Preservative

This ingredient is a preservative, antimicrobial, and emulsifier. It is often used in cosmetics for its ability to cleanse, condition, and reduce static.

Cetrimonium chloride is a quaternary ammonium salt, meaning it has a water-soluble structure.

We don't have a description for Stearamidopropyl Dimethylamine yet.

Isopropyl Alcohol is more commonly known as rubbing alcohol. It is most commonly used as a solvent, meaning it helps other ingredients dissolve.

This ingredient is an astringent alcohol. Astringent alcohols may also irritate skin as they high amounts may strip away your skin's natural oils.

Other types of astringent alcohols include:

According to the National Rosacea Society based in the US, you should be mindful of products with these alcohols in the top half of ingredients.

Any type of sanitizing product will have high amounts of alcohol to help kill bacteria and viruses.

Learn more about Isopropyl Alcohol
Emulsifying

Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.

It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.

The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.

Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).

True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.

Because it is derived from lauric acid, it may not be fungal acne safe.

Learn more about Polysorbate 20
Emulsifying

We don't have a description for Trideceth-12 yet.

Buffering, Exfoliating

Glycolic Acid is arguably the most famous alpha hydroxy acid (AHA) with tons of research backing its benefits.

It is found naturally in sugar cane but the form used in skincare is usually synthetic for purity and stability.

Glycolic acid removes the top layer of dead skin cells to allow newer and fresher ones to emerge.

AHAs work by breaking down the structural ā€œglueā€ that holds old skin cells in place. When that buildup is gone, your skin can renew itself more efficiently.

Research also shows glycolic acid stimulates collagen production, helping to firm and thicken the skin over time. This is one of its biggest advantages over other AHAs.

Overall, glycolic acid helps with:

Fun fact: Glycolic acid boosts skin hydration by helping it produce molecules that increase hyaluronic acid naturally.

To work best, glycolic acid products should have a pH between 3-4 (that’s where exfoliation is most effective but still gentle on skin).

The pH and concentration of a product are key to its effectiveness:

It is normal to feel a slight stinging sensation when using glycolic acid. This usually fades as your skin adjusts.

Because glycolic acid has the smallest molecular size in the AHA family, it can penetrate deeper, which enhances its effectiveness but also makes it more likely to irritate sensitive skin.

If your skin is very sensitive or prone to rosacea, glycolic acid may be too strong; in that case, try milder options like lactic acid or a PHA instead.

Recent studies suggest glycolic acid might even help protect against UV damage. But don’t skip sunscreen! Freshly exfoliated skin is more sensitive to the sun.

Glycolic acid is a skincare superstar. It smooths, brightens, hydrates, and firms the skin. Unless you’re highly sensitive, it’s well worth adding to your routine.

Read more about some other popular AHA's here:

Learn more about Glycolic Acid

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Learn more about Disodium EDTA
Preservative

Diazolidinyl Urea is an antimicrobial preservative. It is commonly used to prevent bacterial, yeast, and mold growth.

Diazolidinyl Urea slowly breaks down into formaldehyde, an effective microbe killer but also a known allergen/carcinogen.

Some people who are allergic to imidazolidinyl urea also react to diazolidinyl urea. It ranked as the 14th most common allergen in patch tests from 2005–06.

Safety reviews show that at concentrations under 0.5%, the formaldehyde released remains below the accepted safety limit, making it considered safe for cosmetic use.

Ultimately, its safety depends on individual skin sensitivity and personal comfort with formaldehyde-releasing preservatives.

Learn more about Diazolidinyl Urea

Iodopropynyl Butylcarbamate (IPBC) is a preservative that is especially good at getting fungi and mold out of your cosmetics.

IPBC works by leveraging the antimicrobial properties of its iodine containing structure. Iodine has been used as a germicide since the late 1800s and IPBC is a more refined and stable derivative of it.

It is typically used at very low levels in cosmetics, with most formulations using 0.0125% or less (well below its approved maximum).

In the EU, IPBC concentration limits are set at 0.02% in rinse-off products and 0.01% in leave-on products.

Though IPBC is a relatively uncommon contact allergen, patch testing studies show positive reaction rates ranging from 0.3%-0.9% of patients tested. This is still quite low compared to preservatives like methylisothiazolinone which sits at around 4-5%.

Researchers note that existing iodine sensitives or rubber allergies may be the cause of this as IPBC shares a structure with both thiuram (used in rubber) and iodine.

Be sure to patch test if you are unsure and speak with a medical professional about using this ingredient.

Learn more about Iodopropynyl Butylcarbamate
Perfuming, UV Absorber

Benzyl Salicylate is a solvent and fragrance additive. It is an ester of benzyl alcohol and salicylic acid. This ingredient can be naturally found in some plants and plant extracts.

In fragrances, Benzyl Salicylate may be a solvent or a fragrance component. In synthetic musk scents, it is used as a solvent. For floral fragrances such as lilac and jasmine, it is used as a fragrance component. The natural scent of Benzyl Salicylate is described as "lightly-sweet, slightly balsamic".

While Benzyl Salicylate has been associated with contact dermatitis and allergies, emerging studies show it may not be caused by this ingredient alone.

However, this ingredient is often used with fragrances and other components that may cause allergies. It is still listed as a known allergen in the EU. We recommend speaking with a professional if you have concerns.

Another study from 2021 shows Benzyl Salicylate may have anti-inflammatory properties.

Learn more about Benzyl Salicylate
Perfuming, Tonic

Geraniol is used to add fragrance/parfum to a product. It is the main component of citronellol. It is a monoterpenoid and an alcohol.

Monoterpenes are naturally found in many parts of different plants.

Geraniol can be found in many essential oils including Rose Oil and Citronella Oil. The scent of Geraniol is often described as "rose-like". Many foods also contain Geraniol for fruit flavoring.

Geraniol can irritate the skin when exposed to air. However, irritation depends on the ability of geraniol to penetrate into the skin. In general, geraniol is not able to penetrate skin easily.

Geraniol is colorless and has low water-solubility. However, it is soluble in common organic solvents.

Like citronellol, it is a natural insect repellent.

2,6-Octadien-1-ol, 3,7-dimethyl-, (2E)-

Learn more about Geraniol
Perfuming, Solvent

Limonene is a fragrance that adds scent and taste to a formulation.

It's found in the peel oil of citrus fruits and other plants such as lavender and eucalyptus. The scent of limonene is generally described as "sweet citrus".

Limonene acts as an antioxidant, meaning it helps neutralize free radicals.

When exposed to air, oxidized limonene may sensitize the skin. Because of this, limonene is often avoided by people with sensitive skin.

The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.

Learn more about Limonene
Perfuming

Linalool is a fragrance and helps add scent to products. It's derived from common plants such as cinnamon, mint, citrus, and lavender.

Like Limonene, this ingredient oxidizes when exposed to air. Oxidized linalool can cause allergies and skin sensitivity.

This ingredient has a scent that is floral, spicy tropical, and citrus-like.

Learn more about Linalool
Masking, Perfuming

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of ā€œFRAGRANCEā€ or ā€œPARFUMā€ according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Learn more about Parfum

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Where it's from

Regis is a American brand

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Ā· Updated September 22, 2025 Added by BlackCat808