AMPLE:N Blemi Shot Toning Suncare SPF 50+ PA++++

Another great benefit? This ingredient is highly photostable so it won't degrade easily under sunlight.

A common myth is that mineral UV filters are widely believed to primarily reflect UV light.

However, modern research shows titanium dioxide absorbs UV radiation like chemical filters (~95% absorption & 5% reflection).

Zinc oxide has great skin soothing properties so you'll likely find this in sunscreens formulated for sensitive skin or babies/children. It is unlikely to cause "eye sting" like other sunscreen ingredients.
Regulatory agencies consider zinc oxide to be non-toxic and safe. It has also been shown to not penetrate the skin.

Unfortunately, this ingredient does leave a visible white cast. This is why mineral sunscreens are often less cosmetically elegant than chemical or hybrid ones.

In cosmetics, zinc oxide can be found in both non-nano and nano-sized forms. The nano version is used to reduce white cast and improve the texture of sunscreen formulas.

There are ongoing concerns surrounding nano-zinc oxide's impact on marine ecosystems and whether it can be absorbed into skin.

Regarding marine ecosystems and coral reefs, there is no conclusive evidence that any form of zinc oxide (or any other sunscreen ingredients) will cause harm. The science is still developing but many consumers are keeping a close eye on this issue.

Please note, many destinations have reef-safety sunscreen rules. For instance, the U.S. Virgin Islands advises all visitors to use non-nano mineral sunscreens.

There has also been some stir about whether micronized or nano zinc oxide has potential photoxicity and absorption through the skin/lungs.

An in-vitro (done in a test tube or petri dish) study demonstrated micronized zinc oxide to have potential phototoxicity. There's no need to fret; the EU Commission's Scientific Committee on Consumer Safety has stated, "The relevance of these findings needs to be clarified by appropriate investigations in vivo." Or in other words, further studies done on living organisms are needed to prove this.

Current research shows zinc oxide nanoparticles do not penetrate intact or sunburned skin. They either remain on the surface or in the outermost layer of dead skin (stratum corneum).

Zinc oxide is one of only two classified mineral UV filters with titanium dioxide being the other one.

Fun fact: Zinc has been used throughout history as an ingredient in paint and medicine. An Indian text from 500BC is believed to list zinc oxide as a salve for open wound. The Ancient Greek physician Dioscorides has also mentioned the use of zinc as an ointment in 1AD.

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

DHHB has been approved by the EU, Japan, Taiwan, and South America for use up to 10%. Unfortunately, it has not been approved for use in the US or Canada due to slow regulatory processes.

This ingredient is soluble in oils, fats, and lipids.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

This ingredient is not water-soluble.

On top of that - it is highly photostable and helps prevent the photodegration of other sunscreen ingredients such as avobenzone.

Tinosorb S is allowed in the EU, Australia, and Asia. It is close to being approved by the FDA and we'll hopefully get this ingredient in the U.S. by late 2026.

Fun fact: Tinosorb S is the most effective UV absorber at maximum concentration (measured by SPF) permitted in the EU.

This ingredient is oil-soluble, so your oil-cleansers will take this right off at night.

Ethylhexyl Triazone is oil soluble, oderless and colorless, which mean it is able to be incorporated into a variety of different formulations.

It is not currently available within the United States due to slow changing FDA regulations. Outside of the US, it is used in formulations at concentrations up to 5%.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

This ingredient is volatile which means it will mostly evaporate (but it evaporates slower than older cyclomethicones, like Cyclotetrasiloxane).

Typical concentration ranges from 1-30% depending on if it's being used to tweak the feel of a product or acting as the main emollient.

Tinosorb M covers a range of 280-400 nm and is photostable. This ingredient is neither oil or water soluble.

Tinosorb M is not available in the US. However, it is available in the EU and Asia.

It's sister, Tinosorb S, is set to be approved in the US by late 2025 (fingers crossed!).

It helps with dark spot fading by interfering with the process of skin darkening, helping to reduce hyperpigmentation. Like other forms of vitamin C, this ingredient encourages the skin to create more collagen.

As an antioxidant, it helps fight free-radicals. Free-radicals are molecules that may damage your skin cells.

One study found Ascorbyl Tetraisopalmitate to degrade in sunlight, but is stabilized when combined with acetyl zingerone.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.

A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.

Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.

One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.

Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.

The composition (and benefits) of the extract will depend on which part of the plant it comes from.

Some studies suggest this ingredient may inhibit pigment production in the skin to help even out skin tone.

One manufacturer claims this ingredient to have a pH range of 2-8 and to be biodegradable.

This ingredient is also known as Sepimax Zen.

It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.

A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.

Because it has a neutral charge, it is compatible with a wide range of ingredients and stays stable across a broad pH range/water hardiness conditions.

Patch testing has shown it to have the lowest irritation potential among common cleansing surfactants (like SLS).

Typical use levels range from 5-20% in rinse-off cleansers.

One thing worth knowing: The American Contact Dermatitis Society named the parent family, alkyl glucosides, "Allergen of the Year" in 2017. The prevalence of allergy is pretty low but be sure to patch test if you've reacted to "gentle" or sulfate-free cleansers before.

This ingredient is fungal acne safe because the fatty alcohol portion of this ingredient is below the C11-24 chain length that Malassezia can metabolize.

Due to this ingredient having a similar composition to cetearyl alcohol, this ingredient may not be malassezia folliculitis safe. However, the risk is low and has been only shown by a single study, so SkinSort does not currently flag C14-22 Alcohols as a fungal acne trigger.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Read more about some other popular AHA's here:

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Due to it being made from stearic acid, this ingredient may not be Malassezia safe.

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

This ingredient is typically used at low levels (up to 2.5% in eyeshadow and 1% in lipstick).

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.