Vichy LiftActiv Pure Retinol Serum for Deep Wrinkles Versus Is Clinical Pro-Heal Serum Advance
Overview
What they are
These products are both reef safe serums. They have a total of 8 ingredients in common
Cool Features
They both contain retinoid and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any common allergens, parabens or silicones
What's Inside
They both contain harsh alcohols
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Vichy LiftActiv Pure Retinol Serum for Deep Wrinkles 30 ingredients
Is Clinical Pro-Heal Serum Advance 17 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
Vichy LiftActiv Pure Retinol Serum for Deep Wrinkles 30 ingredients
Is Clinical Pro-Heal Serum Advance 17 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
Humectant
Pentylene Glycol
Skin ConditioningIsononyl Isononanoate
EmollientAlcohol Denat.
Antimicrobial
Dicaprylyl Ether
Emollient
Glycine Soja Oil
Emollient
Propylene Glycol
Humectant
PEG-6 Caprylic/Capric Glycerides
EmulsifyingHydrolyzed Rice Protein
Skin ConditioningHydroxyacetophenone
Antioxidant
Palmitoyl Tetrapeptide-7
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
Antioxidant
Sodium Hyaluronate
Humectant
Sodium Hydroxide
BufferingTrisodium Ethylenediamine Disuccinate
Vitreoscilla Ferment
Skin ConditioningRetinol
Skin Conditioning
Dicaprylyl Carbonate
EmollientAmmonium Polyacryloyldimethyl Taurate
Emulsion StabilisingButylene Glycol
Humectant
Caprylyl Glycol
EmollientCarbomer
Emulsion StabilisingGlyceryl Isostearate
Emollient
Polysorbate 20
Emulsifying
PPG-6-Decyltetradeceth-30
EmulsifyingSodium Lactate
BufferingTocopherol
Antioxidant
Xanthan Gum
EmulsifyingWater, Glycerin, Pentylene Glycol, Isononyl Isononanoate, Alcohol Denat., Dicaprylyl Ether, Glycine Soja Oil, Propylene Glycol, PEG-6 Caprylic/Capric Glycerides, Hydrolyzed Rice Protein, Hydroxyacetophenone, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Hyaluronate, Sodium Hydroxide, Trisodium Ethylenediamine Disuccinate, Vitreoscilla Ferment, Retinol, Dicaprylyl Carbonate, Ammonium Polyacryloyldimethyl Taurate, Butylene Glycol, Caprylyl Glycol, Carbomer, Glyceryl Isostearate, Polysorbate 20, PPG-6-Decyltetradeceth-30, Sodium Lactate, Tocopherol, Xanthan Gum
Water
Skin ConditioningAscorbic Acid
Antioxidant
Laureth-4
Emulsifying
Alcohol Denat.
Antimicrobial
Pentylene Glycol
Skin ConditioningPropylene Glycol
Humectant
Triethanolamine
BufferingTocopherol
Antioxidant
Glycerin
Humectant
Bioflavonoids
Skin ConditioningRetinol
Skin Conditioning
Olea Europaea Leaf Extract
Perfuming
Zinc Sulfate
Antimicrobial
Polyporus Umbellatus Extract
Skin ProtectingArbutin
Antioxidant
Polysorbate 20
Emulsifying
Phenoxyethanol
Preservative
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.
This ingredient gets a bad rep because it is irritating and drying - mostly due to its astringent property. Astringents draw out natural oils in tissue, constricting pores and leaving your skin dried out.
However, alcohol denat. is not all that bad.
Due to its low molecular weight, alcohol denat. tends to evaporate quickly. One study on pig skin found half of applied alcohol evaporated in 10 seconds and less than 3% stayed on skin.
This also helps other ingredients become better absorbed upon application.
Studies are conflicted about whether this ingredient causes skin dehydration. One study from 2005 found adding emollients to propanol-based sanitizer decreased skin dryness and irritation. Another study found irritation only occurs if your skin is already damaged.
Small amounts of alcohol are generally tolerated by oily skin or people who live in humid environments.
The rule of thumb is if this alcohol is near the end of an ingredients list, it will probably not affect your skin much.
Also...
This ingredient has antimicrobial and solvent properties.
The antimicrobial property helps preserve products and increase their shelf life. As a solvent, it helps dissolve other ingredients.
Other types of astringent alcohols include:
Learn more about Alcohol Denat.Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolPolysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.
Another role of this ingredient is preventing a product from melting or freezing. Propylene glycol also adds antimicrobrial properties to a product, elongating product lifespan.
This ingredient is considered an organic alcohol and commonly added into both cosmetics and foods.
Those with sensitive skin or conditions may develop a rash when using this ingredient.
Learn more about Propylene GlycolRetinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
Why is retinol famous?
It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.
Retinol is proven to:
This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.
Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).
Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
We recommend speaking with a medical professional about using this ingredient during pregnancy.
Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.
Read about Tretinoin
Learn more about RetinolTocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Vichy LiftActiv Pure Retinol Serum for Deep Wrinkles 30 ingredients
Is Clinical Pro-Heal Serum Advance 17 ingredients
