Color: Clear
 

This anti-aging lip moisturizer is formulated around Squalane and Palmitoyl Tripeptide-1 to soften the look of wrinkles and hydrate lips.

This anti-aging serum is formulated around Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and refine skin texture.

Lip Moisturizer
Serum
British United Kingdom
British United Kingdom

What's inside

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

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Light 60% Works Well 40% Hydrating 40%
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Great Value 100% Light 100% No Scent 100%

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning

Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.

That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.

Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.

In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.

Human clinical data is promising, but modest:

A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.

A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.

You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.

Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.

Learn more about Palmitoyl Tripeptide-1

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