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Updated on February 15, 2024

Overview

What they are

These products are both fungal acne (malassezia) safe and reef safe . They have a total of 3 ingredients in common

Cool Features

They both contain hyaluronic acid

Suited For

They're both likely to be good for anti aging, dry skin and brightening skin

Free From

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

ma:nyo Bifida Complex Ampoule
ma:nyo Bifida Complex Ampoule
Ampoule
Korean Brand South Korea
S.NATURE Aqua Squalane Serum

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Benefits

Concerns

Ingredients Side-by-side

found in both products
Bifida Complex Ampoule
Bifida Ferment Lysate Skin Conditioning
Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.

Lactobacillus/Pumpkin Fruit Ferment Filtrate Skin Conditioning

We don't have a description for Lactobacillus/Pumpkin Fruit Ferment Filtrate.

Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Acetyl Hexapeptide-8 Humectant, Skin Conditioning
Peptide Icon
PeptidePeptide Icon

Acetyl Hexapeptide-8 is a peptide. A common name for this peptide is Argireline.

Aureobasidium Pullulans Ferment Skin Conditioning

We don't have a description for Aureobasidium Pullulans Ferment.

Hydrolyzed Algin

We don't have a description for Hydrolyzed Algin.

Caffeine Skin Conditioning

Caffeine is most associated with coffee, tea, and cacao. In skincare, it helps with calming inflammation and anti-aging.

Panax Ginseng Root Extract Emollient, Skin Protecting, Tonic
Helps hydrate Dry Skin IconHelps reduce Skin Redness Icon
2 Benefits

Panax Ginseng Root is a popular herb from Asia. This root contains antioxidants, favonoids, and vitamins B12 and D.

Panax Ginseng Callus Culture Extract Skin Conditioning

This ingredient comes from the callus cells of ginseng.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Epigallocatechin Gallate Antioxidant
Antioxidant Icon
AntioxidantAntioxidant Icon

EGCG is most famous for being found in green tea. It is a type of catechin, a potent antioxidant.

Zanthoxylum Piperitum Fruit Extract Skin Conditioning

Zanthoxylum Piperitum Fruit Extract comes from the Japanese Pepper, also known as the Prickly Ash. This plant is native to the Korean peninsula and Japan.

Pulsatilla Koreana Extract Skin Conditioning

Pulsatilla Koreana Extract comes from the Korean pasque flower. This flower is used in traditional Korean medicine.

Unknown Full details ->
Usnea Barbata Extract

We don't have a description for Usnea Barbata Extract.

Unknown Full details ->
Copper Tripeptide-1 Skin Conditioning
Peptide IconHelps with Anti-Aging Icon
PeptidePeptide Icon Helps with Anti-AgingHelps with Anti-Aging Icon

Copper Tripeptide-1 is a peptide naturally found in body fluids. Peptides are building blocks for protein.

Physalis Alkekengi Fruit Extract Skin Conditioning

We don't have a description for Physalis Alkekengi Fruit Extract.

Unknown Full details ->
Methyl Gluceth-20 Humectant, Moisturising

Methyl Gluceth-20 is a humectant. Humectants help draw moisture from the air to your skin.

Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Adenosine Skin Conditioning
Helps with Anti-Aging IconGood for Scar Healing Icon
2 Benefits

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Aqua Squalane Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Methylpropanediol Solvent

Methylpropanediol is a synthetic solvent and humectant.

1,2-Hexanediol Skin Conditioning, Solvent

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

Betaine Humectant, Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon
3 Benefits

Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.

Laminaria Japonica Extract Skin Protecting

Laminaria Japonica Extract comes from a kelp more commonly known as 'sweet kelp'. It is commonly eaten in Japan, Korea, and China.

Eclipta Prostrata Leaf Extract Skin Conditioning

Eclipta Prostrata Leaf Extract comes from the false daisy plant. False daisy contains antioxidant compounds such as flavonoids.

Hamamelis Virginiana Extract Antiseborrhoeic, Astringent, Skin Conditioning
Can worsen Dry Skin Icon
Can worsen Dry SkinCan worsen Dry Skin Icon

Hamamelis Virginiana Extract comes from the witch hazel plant.

Disliked Full details ->
Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Hydrogenated Lecithin Emulsifying, Skin Conditioning

Hydrogenated Lecithin is created from the hydrogenation of lecithin. Hydrogenation is a chemical reaction between molecule hydrogen and another element.

Panthenol Skin Conditioning
0 / 0 Helps reduce irritation Icon
Helps reduce irritationHelps reduce irritation Icon

Panthenol is a common ingredient that helps hydrate and soothe the skin. It can be found naturally in our skin and hair.

0 Com. / 0 Irr.
Allantoin Skin Conditioning, Skin Protecting, Soothing
0 / 0 Helps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon
3 Benefits

Allantoin plays a role in soothing and moisturizing the skin. Because of this, it is often added to products with strong active ingredients.

0 Com. / 0 Irr.
Fructooligosaccharides Humectant, Skin Conditioning

Fructooligosaccharides is an alternative sweetener. It is often derived from the blue agave plant.

Beta-Glucan Skin Conditioning
Helps reduce Skin Redness Icon
Helps reduce Skin RednessHelps reduce Skin Redness Icon

Beta-Glucan is a polysaccharide. It can be derived from the cell walls of seaweed, oats, yeast, and fungi.

Hydrolyzed Hyaluronic Acid Humectant, Skin Conditioning
Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Hydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.

Squalane Emollient, Skin Conditioning
1 / 0 Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

1 Com. / 0 Irr.
Hydroxypropyltrimonium Hyaluronate

This form of hyaluronic acid is produced through fermentation.

Sodium Acetylated Hyaluronate Humectant
Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Acetylated Hyaluronate is a type of Hyaluronic Acid.

Hydrolyzed Sodium Hyaluronate Skin Conditioning

This ingredient is created by putting sodium hyaluronate through hydrolysis.

Hyaluronic Acid Humectant, Moisturising, Skin Conditioning
Hyaluronic Acid IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation Icon
Hyaluronic AcidHyaluronic Acid Icon 4 Benefits May cause irritationMay cause irritation Icon

Hyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.

Sodium Hyaluronate Crosspolymer Humectant, Skin Conditioning
Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate Crosspolymer is a type of hyaluronic acid. In fact, it is modified version of hyaluronic acid.

Potassium Hyaluronate Skin Conditioning

We don't have a description for Potassium Hyaluronate.

Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Tromethamine Buffering, Masking

Tromethamine is an aliphatic compound. An aliphatic compound is an organic compound with open-chained carbon atoms. It is synthetically created. Tromethamine is used to balance pH and improve texture.

Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Humectant, Masking, Skin Conditioning
Mixed

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.

Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.

Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Skin Conditioning
Loved

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate

Ingredient Ratings

Here's what our community thinks of the ingredients in these two products.

Bifida Complex Ampoule
14
3
3
liked
mixed
disliked
not rated
Aqua Squalane Serum
18
6
4
liked
mixed
disliked
not rated

When to use

109 Routines
40% use in am
60% use in pm
94% use every day
When to use See routines that use it ->
9 Routines
44% use in am
56% use in pm
100% use every day

Reviews

Here's what our community thinks

ma:nyo Bifida Complex Ampoule 20 ingredients

5.0 /5
from 2 ratings
Hydrating (2) No Scent (2) Works Well (2)
nja's avatar

nja

5 months ago · Sensitive Skin
Review

This is some pretty amazing stuff, it's what makes my skin glow! Bifida is great for the skin barrier and pumpkin fruit ferment filtrate has...

This is some pretty amazing stuff, it's what makes my skin glow! Bifida is great for the skin barrier and pumpkin fruit ferment filtrate has exfoliation properties. It also has peptides and niacinamide. Basically te entire INCI is amazing and it's also FA safe. The other version - Bifida BIOME Complex Ampoule - is *not* FA safe but it's very easy to get them mixed up because they look identical.
This ampoule exfoliates the skin and quite effectively, at least in my experience! So if you have very sensitive skin or are using any actives, keep that in mind. My skin gets a little flushed with this but I am using tretinoin. For now I use it once a week but when my skin gets totally used to tret, I plan on using it more because I love it!! It is kind of oily on the skin but it doesn't bother me when it works so well. The glow it gives is unmached!!

ReganAllen_429's avatar

ReganAllen_429

7 hours ago · Combination Skin
Review

So I have oily, sensitive, and acne prone skin and let me just say—this serum is absolutely incredible! My skin is so finicky about products and...

So I have oily, sensitive, and acne prone skin and let me just say—this serum is absolutely incredible! My skin is so finicky about products and ingredients that normally work wonders for others. So, when I heard the positive reviews from others about this product I was prepared for it to be yet another flop…But THIS serum omg! It’s outstanding. I notice my skin is less red after using this, my pimples decrease, AND I swear it helps sooth and lessen my hormonal acne. 10/10 highly recommend!

S.NATURE Aqua Squalane Serum 28 ingredients

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