Sepai De-Puff Eyes
A eye moisturizer with 45 ingredients, including vitamin C, exfoliants, and peptides.
Overview
What it is
Eye moisturizer with 45 ingredients that contains exfoliants, peptides and Vitamin C
Cool Features
It is vegan, cruelty-free, fungal acne (malassezia) safe, and reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
Fun facts
Sepai is from Spain.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin ConditioningGlycerin
HumectantLactobacillus Ferment
Skin ConditioningPropanediol
SolventPueraria Lobata Root Extract
HumectantCaffeine
Skin ConditioningAcetyl Carnitine Hcl
Skin ConditioningAesculus Hippocastanum Extract
AntioxidantAcetyl Tetrapeptide-5
HumectantRuscus Aculeatus Root Extract
AstringentDecapeptide-2
Skin ConditioningHedera Helix Extract
AntimicrobialTripeptide-3
Skin ConditioningHamamelis Virginiana Extract
AntiseborrhoeicSolidago Virgaurea Extract
Skin ConditioningRhus Coriaria Leaf/Stem Extract
AntioxidantAstragalus Membranaceus Root Extract
EmollientVitis Vinifera Leaf Extract
Skin ConditioningSigesbeckia Orientalis Extract
Skin ConditioningArnica Montana Flower Extract
MaskingCamellia Sinensis Leaf Extract
AntimicrobialRosmarinus Officinalis Leaf Extract
AntimicrobialSpirulina Platensis Powder
Skin ProtectingCitrus Medica Limonum Peel Extract
EmollientLaminaria Digitata Extract
Skin ProtectingFucus Vesiculosus Extract
EmollientAlbizia Julibrissin Bark Extract
MaskingCitrus Aurantium Amara Peel Extract
MaskingPanthenol
Skin ConditioningSerine
MaskingPullulan
Sclerotium Gum
Emulsion StabilisingXanthan Gum
EmulsifyingSilica
AbrasiveLecithin
EmollientPotassium Sorbate
PreservativeSodium Hydroxide
BufferingSodium Benzoate
MaskingSorbic Acid
PreservativeButylene Glycol
HumectantAroma
Mica
Cosmetic ColorantCI 77891
Cosmetic ColorantCI 77491
Cosmetic Colorant3-O-Ethyl Ascorbic Acid
Skin ConditioningWater, Glycerin, Lactobacillus Ferment, Propanediol, Pueraria Lobata Root Extract, Caffeine, Acetyl Carnitine Hcl, Aesculus Hippocastanum Extract, Acetyl Tetrapeptide-5, Ruscus Aculeatus Root Extract, Decapeptide-2, Hedera Helix Extract, Tripeptide-3, Hamamelis Virginiana Extract, Solidago Virgaurea Extract, Rhus Coriaria Leaf/Stem Extract, Astragalus Membranaceus Root Extract, Vitis Vinifera Leaf Extract, Sigesbeckia Orientalis Extract, Arnica Montana Flower Extract, Camellia Sinensis Leaf Extract, Rosmarinus Officinalis Leaf Extract, Spirulina Platensis Powder, Citrus Medica Limonum Peel Extract, Laminaria Digitata Extract, Fucus Vesiculosus Extract, Albizia Julibrissin Bark Extract, Citrus Aurantium Amara Peel Extract, Panthenol, Serine, Pullulan, Sclerotium Gum, Xanthan Gum, Silica, Lecithin, Potassium Sorbate, Sodium Hydroxide, Sodium Benzoate, Sorbic Acid, Butylene Glycol, Aroma, Mica, CI 77891, CI 77491, 3-O-Ethyl Ascorbic Acid
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinThis ingredient is made when the Lactobacillus bacteria (the same kind that makes yogurt and kimchi) are allowed to ferment a nutrient medium.
As it ferments, it collects lactic acid, peptides, enzymes, and other bioactive metabolites to provide:
A 2023 review noted that probiotic fermentation ingredients like this one can enhance antioxidant capacity, reduce UV-induced oxidative damage, and support barrier function.
One clinical study from the same year showed a Lactobacillus ferment lysate significantly reduced transepidermal water loss and improved skin hydration.
Another review highlighted that topical Lactobacillus-based preparations can improve ceramide levels in the stratum corneum, support barrier integrity, and even help reduce S. aureus colonization in atopic dermatitis.
Why is this so cool?
Basically, your skin's outer layer works as a brick wall; skin cells are bricks and ceramides are the mortar holding it together. Moisture escapes, irritants get in, and your skin gets dry and reactive when ceramide levels drop. On top of that, "bad" skin bacteria S. aureus loves to move in when your barrier is weak to make inflammation and irritation worse.
So Lactobacillus ferment is basically patching the wall and evicting the troublemaker when it boosts ceramide production and help keep S. aureus in check.
On top of all this, it also acts as a mild antimicrobial preservative booster.
Just so you know, most studies focus on specific strains or the lysate form rather than this generic "Lactobacillus Ferment", so results can vary.
Though it's a promising ingredient, it doesn't have decades of robust clinical data behind it just yet.
Lactobacillus Ferment is generally considered safe for fungal-acne prone skin. The key thing to understand is that it comes from bacteria, not yeast or fungus.
Yeast-derived ferments (like galactomyces) have been shown to activate a protein that's linked to Malassezia-related skin issues whereas lactobacillus doesn't have that problem.
Its byproducts also don't contain the types of fatty acids (C11-24 chain lengths) that Malassezia feeds on.
Learn more about Lactobacillus FermentPropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolThis ingredient comes from the Kudzu root.
Caffeine is a naturally occurring plant compound found in coffee beans, tea leaves, cocoa pods, and guarana.
As an antioxidant, caffeine protects your skin from free radical damage caused by UV exposure and envionrmnetal stressors.
Early research also shows that caffeine can help calm redness, soothe irritated skin, and support hair growth by stimulating microcirculation in the scalp.
You might have seen eye creams marketing caffeine as a depuffing ingredient. This is because it is a vasoconstrictor meaning it can temporarily constrict blood vessels, though clinical evidence for this specific use is still limited.
Most skincare products contain this ingredient at concentrations between 1-6%. It is able to penetrate skin easily regardless of skin type or thickness.
Just so you know, a very small number of case reports describe caffeine-induced allergy. This ingredient is generally well-tolerated, non-irritating, and non-sensitizing for the majority of people.
Learn more about CaffeineAcetyl Carnitine Hcl is an antioxidant
Aesculus Hippocastanum Extract is derived from horse chestnut native to Southeastern Europe.
It is an antioxidant and helps soothe skin. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
Acetyl Tetrapeptide-5 is a peptide that goes by another name, eyeseryl, due to claims that it can help reduce eye puffiness.
The manufacturer claims this ingredient reduces eye puffiness by:
An in-vivo study from the manufacturer found 95% of volunteers saw eye bag improvement by the end of the study.
Eye puffiness is caused by two major factors: fluid retention and fat.
Those with fluid retention may see improvement from using this ingredient. However, those with eye fat will need surgical intervention in order to get rid of puffiness.
Learn more about Acetyl Tetrapeptide-5Ruscus Aculeatus Root Extract can help to reduce redness.
Decapeptide-2 is a peptide.
We don't have a description for Hedera Helix Extract yet.
Tripeptide-3 is a peptide.
Hamamelis Virginiana Extract comes from the witch hazel plant.
Unless it is specified to be non-alcohol, many types of witch hazel ingredients are distilled in denatured alcohol.
Witch Hazel has astringent, anti-inflammatory, antioxidant, and antibacterial properties.
The tannin content of witch hazel constrict the appearance of pores by drying out proteins. Witch hazel water gets anti-inflammatory and antibacterial properties from its catechin and gallic acid content.
However, witch hazel may be skin-sensitizing due to the tannin and fragrance compounds.
North American Indigenous groups have used witch hazel to help treat inflammation for centuries.
Learn more about Hamamelis Virginiana ExtractWe don't have a description for Solidago Virgaurea Extract yet.
Rhus Coriaria Leaf/Stem Extract is an antioxidant.
Astragalus Membranaceus Root Extract is from an herb called Huang Qi. The roots of this plant have traditionally used in traditional Chinese medicine.
This ingredient contains hydrating, antioxidant, and anti-inflammatory compounds such as polysaccharides, saponins, and flavonoids. These compounds have also been studied for its effects on skin repair like fibroblast activity, growth-factor signaling, and wound closure models. However, human evidence is still limited.
Recent clinical work on a proprietary Astragalus + Centella saponin system showed improvement in skin aging and quality.
Overall, this ingredient is a great supportive ingredient with low irritation risk.
Learn more about Astragalus Membranaceus Root ExtractVitis Vinifera Leaf Extract comes from leaves on a grape vine. It helps hydrate and soften the skin.
We don't have a description for Sigesbeckia Orientalis Extract yet.
Arnica Montana Flower is more commonly known as Wolf's Bane. While this flower has been used in traditional medicine, its skin benefits are in question.
The FDA considers Wolf's Bane to be an unsafe herb. They advise against taking it orally or applying it to broken skin.
Wolf's Bane has been said to have anti-inflammatory properties. However, studies are conflicting about whether this is true.
According to the Final report on the safety assessment of Arnica montana, this plant has not been found to cause dermal irritation.
This flower contains numerous fatty acids such as palmitic, linoleic, myristic, and linolenic acids. The presence and amount of fatty acids depends on where the flower is harvested.
Like other flowers, this ingredient has a natural fragrance. It can also be used to mask, or cover, the unpleasant scents from other ingredients.
Learn more about Arnica Montana Flower ExtractCamellia Sinensis Leaf Extract (tea extract) is one of the most well-researched plant extracts in skincare with an impressive resume.
Black tea, green tea, and oolong tea are all harvested from the Camellia Sinensis plant.
Studies show green tea extract and its catechins (like epigallocatechin gallate (EGCG)) help your skin cells product energy more efficiently and reducing the number of free-radicals that can damage your skin from the inside.
In lab-grown skin models, this translated to younger, healthier, and stronger skin.
There's also good sun protection data; researchers saw less DNA damage and redness on human skin when green tea was applied before UVB exposure. And the more they applied, the better the protection.
Needless to say, this ingredient shouldn't replace your sunscreen. But it is a great supportive ingredient that you can already find in many sunscreens and antioxidant serums.
A 2009 study found a 2% green tea lotion was effective for mild-to-moderate acne thanks to its anti-inflammatory and mild antimicrobial activity.
The quality of the extract matters a lot here:
Good extracts contain 50-90% catechins while lower quality ones are mostly there for marketing. We recommend reaching out to the brand if you have questions about the quality or source of their ingredients.
Human Repeated Insult Patch Testing showed no irritation or sensitization at use concentrations (0.86% in leave-on products and up to 30% as leaf water).
Learn more about Camellia Sinensis Leaf ExtractThis is a botanical extract from the rosemary plant (the same one you cook with). In skincare, it mostly works as a skin conditioning agent.
Its activity comes from a handful of polyphenols, carnosic acid, carnosol, and rosmarinic acid. Almost 90% of the antioxidant activity of this ingredient can be attributed to canosol and carnosic acid.
These compounds protect your skin two ways:
1) They fight off free radicals, or the unstable molecules from things like sun and pollution that age and damage skin.
2) They help calm inflammation by switching off the chemical signals that tell skin to get red and irritated.
Lab studies also suggest that rosmarinic acid may help protect collagen and slow sugar-related damage to it.
The Cosmetic Ingredient Review has concluded rosemary-derived ingredients to be safe when formulated to be non-sensitizing.
Rosemary can occasionally cause allergic contact dermatitis (due to carnosol), so be sure to patch test if you have reactive or fragrance-sensitive skin.
Learn more about Rosmarinus Officinalis Leaf ExtractSpirulina Platensis Powder comes from the alga called Spirulina platensis. It has wound-healing, antioxidant, and soothing properties.
Antioxidants help protect the skin against free-radical molecules. These molecules may originate from UV rays or pollution. Spirulina Platensis is rich in beta-carotene, a potent antioxidant.
We don't have a description for Citrus Medica Limonum Peel Extract yet.
Laminaria Digitata Extract comes from the dark brown seaweed, Laminaria Digitata. It is a potent antioxidant, which also provides soothing and hydrating benefits.
Many studies show the antioxidant components of Laminaria Digitata to help with anti-inflammation.
This ingredient is rich in amino acids, proteins, sugars, and vitamins. Small amounts of minerals such as phosphorous, iron, potassium, and copper are also found the seaweed.
These components help hydrate and nourish your skin's natural barrier. Having a healthy skin barrier leads to more youthful looking skin and may help reduce the signs of aging.
Laminaria Digitata is found in the northern Atlantic Ocean.
What's the difference between algae and seaweed?
Algae is a broad term that includes seaweed. Not all algae is seaweed.
Fucus Vesiculosus Extract is derived from a type of brown algae.
Algae is an informal term for a group of aquatic organisms that can photosynthesize. It is estimated there are at least 30,000 types of Algae.
Fucus Vesiculosus Extract contains antioxidants. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
Fucus Vesiculosus Extract is also rich in sodium, potassium, and amino acids.
Many different types of algae have different benefits.
Learn more about Fucus Vesiculosus ExtractWe don't have a description for Albizia Julibrissin Bark Extract yet.
We don't have a description for Citrus Aurantium Amara Peel Extract yet.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolSerine is a non-essential amino acid (your body makes it on its own!). It is a major player in your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Serine is one of your NMF's most abundant components that works as a skin-identical humectant. Its hydroxyl group grabs onto water molecules to boost hydration without any heaviness or occlusion.
Research on a hydrogel with serine confirmed this serine got delivered to your stratum corneum and demonstrated enhanced skin moisturization.
Interestingly serine also helps your skin produce filaggrin, a protein that keeps your skin barrier strong and used to create collagen.
Learn more about SerinePullulan is a low viscosity polysaccharide (a long chain carbohydrate) with binding and film forming properties when dissolved in water. It is used to create a "silicone-like" or silky feel in cosmetics without adding viscosity.
According to a manufacturer, this ingredient's ability to easily dissolves makes it a great carrier for active ingredients.
Due to it being edible and tasteless, you'll likely find this ingredient in breath freshener strips. This ingredient is produced from the starch of the fungus, Aureobasidium pullulans.
Pullulan is stable over a broad-range of pH.
Learn more about PullulanSclerotium Gum is a polysaccharide gum made by the fungus, Sclerotium rolfssii. It is similar to xanthan gum.
In cosmetics, Sclerotium Gum is used to thicken the texture and to help stabilize other ingredients.
As an emulsifier, Sclerotium Gum helps prevent ingredients from separating, such as water and oil.
Learn more about Sclerotium GumXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumSilica, also known as silicon dioxide, is a naturally occurring mineral. It is used as a fine, spherical, and porous powder in cosmetics.
Though it has exfoliant properties, the function of silica varies depending on the product.
The unique structure of silica enhances the spreadability and adds smoothness, making it a great texture enhancer.
It is also used as an active carrier, emulsifier, and mattifier due to its ability to absorb excess oil.
In some products, tiny microneedles called spicules are made from silica or hydrolyzed sponge. When you rub them in, they lightly polish away dead skin layers and enhance the penetration of active ingredients.
Learn more about SilicaLecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Learn more about LecithinPotassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Learn more about Potassium SorbateSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoateSorbic Acid is a preservative that stops your product from spoiling by stopping microbes from growing.
As a preservative, it's kind of a specialist: it has a broad spectrum of activity against yeast and molds but is weaker against bacteria. That's why it's often paired with another preservative to cover that gap.
This ingredient is also pretty picky about pH; it performs best at pH 6.5 or below.
At the right pH level, sorbic acid is "active" and can slip through the outer wall of a microbe. Once inside, it turns the cell's interior more acidic to shut down the microbe from the inside.
The EU caps this ingredient at 0.6% while the CIR has concluded it's safe at concentrations up to 1%. It's most often used around 0.05-0.2% in cosmetics.
Though this ingredient is considered low-sensitizing and well-tolerated, a very small number of people may have a contact allergy to it. Be sure to patch test if you have a history of allergies towards preservatives.
Learn more about Sorbic AcidButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolAroma refers to an ingredient, or mixture of ingredients, that impart or mask a flavor.
The name is slightly confusing. This is because INCI associates aroma with flavor instead of smell.
Here is the official definition from the The International Cosmetic Ingredient Dictionary and Handbook:
“Aroma is a term for ingredient labeling used to identify that a product contains a material or combination of materials normally added to a cosmetic to produce or to mask a particular flavor.”
INCI shows the only purpose of aroma to be "flavouring".
However, due to regulation differences, some companies may use aroma in place of parfum.
In Canada, this ingredient only has to be listed in concentrations above 1%.
Learn more about AromaMica is a naturally occurring mineral used to add shimmer and color in cosmetics. It can also help improve the texture of a product or give it an opaque, white/silver color.
Serecite is the name for very fine but ragged grains of mica.
This ingredient is often coated with metal oxides like titanium dioxide. Trace amounts of heavy metals may be found in mica, but these metals are not harmful in our personal products.
Mica has been used since prehistoric times throughout the world. Ancient Egyptian, Indian, Greek, Roman, Aztec, and Chinese civilizations have used mica.
Learn more about MicaCi 77891 is a white pigment from Titanium dioxide. It is naturally found in minerals such as rutile and ilmenite.
It's main function is to add a white color to cosmetics. It can also be mixed with other colors to create different shades.
Ci 77891 is commonly found in sunscreens due to its ability to block UV rays.
Learn more about CI 77891Ci 77491 is also hydrated iron III oxide. It's sole purpose is to give a red/pink hue to products.
Iron III oxides are classified as inorganic chemicals for coloring.
Synthetically created Ci 77491 is considered safer than those naturally found. This is because the synthetically created version may contain less impurities. Iron oxides are generally non-toxic and non-allergenic.
Learn more about CI 77491You might know this ingredient as Ethyl Ascorbic Acid, a more stable version of ascorbic acid.
Like other types of vitamin C, this ingredient has many benefits including reducing wrinkles, skin soothing, dark spot fading, and fighting against free radicals.
3-O-Ethyl Ascorbic Acid interferes with the process of skin darkening, helping to reduce hyperpigmentation. It also encourages the skin to produce more collagen.
Once applied, 3-O-Ethyl Ascorbic Acid is converted to Vitamin C deeper in the skin's layers. This process is slow but makes this ingredient more tolerable for skin.
The optimum pH range for this ingredient is 4 - 5.5
Learn more about 3-O-Ethyl Ascorbic AcidReviews
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Where it's from
Sepai is a Spanish brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated July 15, 2025 • Added by jnm