Esfolio Hyaluronic Acid Moisturizing Ampoule
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Esfolio Hyaluronic Acid Moisturizing Ampoule

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Overview

What it is

Serum with 40 ingredients that contains hyaluronic acid

Cool Features

It is cruelty-free and reef safe

Suited For

It has ingredients that are good for anti aging, dry skin, brightening skin, sensitive skin, scar healing and dark spots

Free From

It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates

Fun facts

Esfolio is from .

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

What's inside (and what isn't)

Ingredients List

Dive into the full list of ingredients.

Key Ingredients

Benefits

Ingredients Explained

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant

Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.

It is a humectant and helps add texture to products. It can make your product thicker.

As a humectant, it helps draw moisture from the air to your skin. This helps your skin stay hydrated.

Learn more about Glycereth-26
Humectant, Skin Conditioning

Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.

This ingredient is best for improving hydration and soothing irritated skin. Studies also show it helps even out skin tone.

Fun fact: Betaine is naturally created in the skin and body. The kind found within cosmetic products can be either plant-derived or synthetic.

Learn more about Betaine
Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Humectant, Skin Conditioning

Sodium Hyaluronate Crosspolymer is a type of hyaluronic acid. In fact, it is modified version of hyaluronic acid.

The structure of Sodium Hyaluronate Crosspolymer allows it to stay in the skin's top layer for a longer period of time. This allows for even more hydration and humectant action than hyaluronic acid.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate Crosspolymer
Humectant, Skin Conditioning

Hydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.

Low molecular weight HA has been shown to hydrate and increase elasticity of the skin. Increasing elasticity is also associated with reduction of wrinkle depth.

One study found topical low molecular weight hyaluronic acid may be considered for the treatment of rosacea in the adult population. However, we always recommend speaking with a professional about your skin concerns.

Hyaluronic acids are a humectant. This means they draw moisture from the air. Hyaluronic acids help moisturize, soothe, and protect the skin.

Read more about other common forms of hyaluronic acid:

Learn more about Hydrolyzed Hyaluronic Acid
Humectant, Moisturising, Skin Conditioning

Hyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.

This ingredient helps hydrate, soothe, and protect the skin.

What makes hyaluronic acid so hydrating? It has the capacity to bind or hold large amounts of water.

Fun fact: It is already naturally found in our bodies, such as the fluids of our eyes and our joints.

Studies find this ingredient to have anti-inflammatory and anti-microbial properties. This can help speed up wound-healing.

Hyaluronic acid can be irritating if the molecule has a low-molecular weight, or if the molecules are small.

One study found low-molecular weight hyaluronic acid to be pro-inflammatory, meaning some people may experience irritation. This is because our bodies use hyaluronic acid in the wound-healing process to signal to our bodies, via irritation, that something needs healing.

The same study found high-molecular weight hyaluronic acid to be anti-inflammatory.

These are some other common types of Hyaluronic Acid:

Learn more about Hyaluronic Acid
Skin Conditioning

This ingredient is created by putting sodium hyaluronate through hydrolysis.

You might know this as 'mini' or 'ultra low-molecular weight' hyaluronic acid. The small molecule size means it is able to travel deeper in the skin.

According to studies, low molecular-weight hyaluronic acid can:

One study from 2011 found ultra-low weight HA to show pro-inflammatory properties. Another study from 2022 found it to downregulate UV-B induced inflammation.

Hydrolysis is a process of changing a molecule using water or enzymes.

This ingredient is water-soluble.

Learn more about Hydrolyzed Sodium Hyaluronate

Vaccinium Macrocarpon Fruit Extract comes from the cranberry fruit. Vaccinium Macrocarpon is the North American species of cranberries native to eastern Canada.

As an astringent, cranberry extract helps tighten the pores by constricting the cells.

Cranberries contain Vitamin E and Vitamin C, both potent antioxidants. It also contains minerals such as manganese and copper.

Learn more about Vaccinium Macrocarpon Fruit Extract
Astringent, Skin Conditioning, Smoothing

We don't have a description for Rubus Idaeus Fruit Extract yet.

Fragaria Chiloensis Fruit Extract comes from the beach strawberry. This is a strawberry native to Pacific coasts of North America, South America, and Hawaii. It likes to grow on sandy beaches.

Beach strawberries have antioxidant and moisturizing properties. They contain many compounds that are potent antioxidants, such as anthocyanins and Vitamin C.

The sugar, or polysaccharides, in strawberries help hydrate the skin by increasing water retention.

Strawberries also contain acids such as ellagic acid, a compound that may protect our skin against UVB damage. Another acid present is citric acid.

Fun fact: The strawberry we buy and eat today was created as a hybrid from the beach strawberry.

Learn more about Fragaria Chiloensis Fruit Extract
Astringent, Masking, Tonic

Blackberry extract is rich in antioxidants and Vitamin C. The majority of antioxidants include flavonoid, phenolic, and anthocyanins.

Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution. This may help reduce the symptoms related to aging.

Skin Protecting, Soothing

This extract comes from the blueberry native to North America. It has great antioxidant and skin soothing properties.

The antioxidant properties from blueberries come from its polyphenolic and vitamin C content. Polyphenols are a compound famous for their antioxidant properties and are commonly found in fruits.

A 2023 study found blueberries to protect skin from UV-B related inflammation. However, this ingredient should not replace your sunscreen.

Learn more about Vaccinium Angustifolium Fruit Extract

This extract comes from the Cabbage Palm, AKA the Açaí berry! It has skin soothing, antioxidant, and anti-aging properties.

Acai berries are rich in antioxidants, including ferulic acid (The famous vitamin C stabilizer). Antioxidants protect your skin against damaging free-radical molecules.

You can also find carbohydrates, lipids, proteins, minerals, vitamin A, and Vitamin C in these berries.

Learn more about Euterpe Oleracea Fruit Extract
Skin Conditioning

Snail Secretion Filtrate is the excretion from snails. It is an effective moisturizer and promotes collagen production.

A popular nickname for this ingredient is 'Snail Mucin'.

Snail mucin has numerous skin benefits:

On top of this, Snail Secretion Filtrate contains a variety of vitamins and minerals. These include copper peptides, Vitamin A, and vitamin E. Vitamins A and E are antioxidants. Antioxidants help fight free-radicals that damage skin cells.

Being cruelty-free means a brand does not experiment on animals.
If you're worried about the well-being of the snails, we recommend looking more into the company of the product. Many brands have developed humane methods to collect snail mucin.

There is much debate on this subject. On one hand, this ingredient comes from an animal. On the other hand, many will argue the ingredient is naturally secreted (like a natural by-product) and therefore vegan. If you have reservations, you can look into Galactomyces Ferment Filtrate or Centella Asiatica Extract as alternatives.

Learn more about Snail Secretion Filtrate
Solvent

We don't have a description for Benzyl Glycol yet.

Masking, Skin Conditioning

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

As a cosmetic ingredient, Arginine has antioxidant properties and can also help repair damaged skin. This ingredient is derived either synthetically or from animals.

Arginine isn't fungal acne safe when used in the presence of other lipids (fats, fatty acids, oils, esters, etc). Oils and fats occur naturally within the skin, so take caution when using Arginine if you're prone to fungal acne.

Learn more about Arginine
Emulsion Stabilising, Gel Forming

Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Humectant, Moisturising

Trehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.

As a humectant, trehalose helps draw moisture from the air to your skin. This helps keep your skin hydrated.

Due to its antioxidant properties, trehalose may help with signs of aging. Antioxidants help fight free-radical molecules, unstable molecules that may damage your skin.

In medicine, trehalose and hyaluronic acid are used to help treat dry eyes.

Some animals, plants, and bacteria create trehalose as a source of energy to survive freeze or lack of water.

Learn more about Trehalose
Skin Conditioning

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Learn more about Panthenol

Glyceryl Acrylate/Acrylic Acid Copolymer is made up of glycerin and polyacrylic acid. It helps hydrate your skin as a humectant.

This ingredient forms a hydrogel that delivers moisturizing, water-based ingredients to the skin. It is also used to thicken a product and to give it a smooth texture.

Acrylic acid itself is toxic, but the polymer form (this ingredient) is too large to penetrate skin, making it non-toxic.

Learn more about Glyceryl Acrylate/Acrylic Acid Copolymer
Humectant, Skin Conditioning

Xylitylglucoside is created from xylitol and glucose, two humectants.

Not surprisingly, this ingredient is also a humectant. It attracts and holds water in your skin, helping to maintain hydration.

This ingredient is most commonly found in a popular trio called Aquaxyl. Aquaxyl is made up of anhydroxylitol(24 - 34%), xylitylglucoside (35 - 50%), and xylitol (5 - 15%).

According to a manufacturer, Aquaxyl is known for a 3-D hydration concept and an anti-dehydration shield to reinforce the outer layer of skin.

Learn more about Xylitylglucoside
Humectant, Skin Conditioning

This ingredient is created from dehydrating xylitol in acidic conditions. Xylitol is a famous sugar and humectant.

Much like its predecessor, anhydroxylitol is a humectant. Humectants attract and hold water to moisturize the skin.

This ingredient is most commonly found in a popular trio called Aquaxyl. Aquaxyl is made up of anhydroxylitol (24 - 34%), xylitylglucoside (35 - 50%), and xylitol (5 - 15%).

According to a manufacturer, Aquaxyl is known for a 3-D hydration concept and an anti-dehydration shield to reinforce the outer layer of skin.

This ingredient is often derived from plants such as wood and sugarcane.

Learn more about Anhydroxylitol
Masking, Solvent

Dipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.

Dipropylene Glycol helps dissolve and evenly distribute ingredients. It also helps decrease viscosity and thin out texture.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Learn more about Dipropylene Glycol
Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.

This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.

Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.

Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.

Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.

Learn more about Pentylene Glycol

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Emulsion Stabilising

We don't have a description for Pvm/Ma Copolymer yet.

Humectant, Skin Conditioning

Xylitol is a humectant and prebiotic. It can help with dry skin.

In studies, xylitol has been shown to improve dry skin. It decreased transepidermal water loss, or when water passes through the skin and evaporates. Xylitol also showed to help improve the biomechanical properties of the skin barrier.

The prebiotic property of xylitol may also help reinforce our skin's natural microbiome. Having a healthy microbiome prevents infection by bad bacteria and helps with hydration.

As a humectant, Xylitol helps draw moisture from both the air and from deeper skin layers. This helps keep skin hydrated.

Xylitol is a sugar alcohol and commonly used as a sugar substitute. It is naturally occurring in plants such as strawberries and pumpkin.

Learn more about Xylitol
Humectant

Glucose is a simple sugar and is the most important source of energy in all organisms.

In skincare, glucose is used to hydrate the skin. It also acts as a prebiotic for our natural biome.

Glucose is hydrating due to its humectant property. As a humectant, glucose draws moisture from the air and from deeper levels in the skin.

Our skin contains many sugars that act as prebiotics and help strengthen our natural microbiome. Having a healthy microbiome helps protect our skin from harmful bacteria and other contaminants.

Studies show glucose may help with fading discoloration and pigmentation. This is because our skin metabolizes glucose into lactic acid. Lactic acid is an AHA that helps exfoliate the top layer of skin.

Learn more about Glucose
Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
Antioxidant

Hydroxyacetophenone is antioxidant with skin conditioning and soothing properties. It also boosts the efficiency of preservatives.

This ingredient is not irritating or sensitizing.

Emulsifying, Skin Conditioning

Hydrogenated Lecithin is created from the hydrogenation of lecithin (a group of phospholipids). Hydrogenation is a chemical reaction between hydrogen and another element.

This ingredient is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Absorbent

Dextrin is used to thicken a product and helps bind ingredients together. It is created from starch and glycogen.

As an emulsifier, dextrin prevents ingredients from separating. This helps elongate a product's shelf life.

Studies show coating UV filters with dextrin prevents these ingredients from being absorbed. This helps UV ingredients last longer on the skin.

Learn more about Dextrin
Emulsion Stabilising

This ingredient is a semi-synthetic polymer created from cellulose. In case you need a refresher, cellulose is the main component of plant cell walls.

Hydroxypropyl Methylcellulose has many uses:

  • emulsifier
  • create a gel-like texture
  • boost foam
Cosmetic Colorant

We don't have a description for CI 77220 yet.

Antimicrobial, Preservative

Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.

Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria.

Chlorphenesin is soluble in both water and glycerin.

Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.

Learn more about Chlorphenesin

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· Published July 2, 2025 Added by tuulialei