Dr. Wu Dermlab Bionanoceramide 2% + NMF 15% Serum
A serum with 61 ingredients, including exfoliants, hyaluronic acid, and ceramides.
Overview
What it is
Serum with 61 ingredients that contains ceramides, exfoliants, hyaluronic acid, peptides and urea
Cool Features
It is reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, sensitive skin, scar healing and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, parabens or sulfates
Fun facts
Dr. Wu is from Taiwan.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin ConditioningButylene Glycol
HumectantGlycerin
HumectantBis-PEG-15 Methyl Ether Dimethicone
EmulsifyingGlycogen
Humectant1,2-Hexanediol
Skin ConditioningPhenoxyethanol
PreservativeCarbomer
Emulsion StabilisingChlorphenesin
AntimicrobialGlycosphingolipids
EmollientPEG-60 Hydrogenated Castor Oil
EmulsifyingSodium Hyaluronate
HumectantPotassium Hydroxide
BufferingXanthan Gum
EmulsifyingDisodium EDTA
Ethylhexylglycerin
Skin ConditioningO-Cymen-5-Ol
AntimicrobialGlyceryl Acrylate/Acrylic Acid Copolymer
HumectantPvm/Ma Copolymer
Emulsion StabilisingSodium Lauroyl Lactylate
EmulsifyingMagnesium PCA
HumectantSodium Lactate
BufferingCopper Tripeptide-1
Skin ConditioningCeramide NP
Skin ConditioningSerine
MaskingSucrose
HumectantUrea
BufferingGlycine
BufferingCeramide AP
Skin ConditioningCholesterol
EmollientPhytosphingosine
Skin ConditioningCalcium Chloride
AstringentOrnithine
Skin ConditioningSea Salt
AbrasiveAlanine
MaskingMagnesium Chloride
Threonine
Histidine
HumectantAspartic Acid
MaskingValine
MaskingProline
Skin ConditioningDipotassium Phosphate
BufferingLysine
Skin ConditioningLeucine
Skin ConditioningTyrosine
MaskingIsoleucine
Skin ConditioningMagnesium Citrate
Skin ConditioningGlucosamine Hcl
Glutamic Acid
HumectantPhenylalanine
MaskingArginine
Masking1-Methylhydantoin-2-Imide
Skin ConditioningAsparagine
MaskingCitrulline
Skin ConditioningUric Acid
BufferingMethionine
Skin ConditioningTaurine
BufferingTryptophan
MaskingCysteine
AntioxidantGlutamine
Skin ConditioningCeramide EOP
Skin ConditioningWater, Butylene Glycol, Glycerin, Bis-PEG-15 Methyl Ether Dimethicone, Glycogen, 1,2-Hexanediol, Phenoxyethanol, Carbomer, Chlorphenesin, Glycosphingolipids, PEG-60 Hydrogenated Castor Oil, Sodium Hyaluronate, Potassium Hydroxide, Xanthan Gum, Disodium EDTA, Ethylhexylglycerin, O-Cymen-5-Ol, Glyceryl Acrylate/Acrylic Acid Copolymer, Pvm/Ma Copolymer, Sodium Lauroyl Lactylate, Magnesium PCA, Sodium Lactate, Copper Tripeptide-1, Ceramide NP, Serine, Sucrose, Urea, Glycine, Ceramide AP, Cholesterol, Phytosphingosine, Calcium Chloride, Ornithine, Sea Salt, Alanine, Magnesium Chloride, Threonine, Histidine, Aspartic Acid, Valine, Proline, Dipotassium Phosphate, Lysine, Leucine, Tyrosine, Isoleucine, Magnesium Citrate, Glucosamine Hcl, Glutamic Acid, Phenylalanine, Arginine, 1-Methylhydantoin-2-Imide, Asparagine, Citrulline, Uric Acid, Methionine, Taurine, Tryptophan, Cysteine, Glutamine, Ceramide EOP
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinBis-PEG-15 Methyl Ether Dimethicone is a type of silicone.
Glycogen is a naturally occurring polysaccharide.
You can find glycogen in our keratinocytes (the cells that produce keratin). It plays an important role in skin hydration and barrier recovery.
Recent research shows topical glycogen can help improve skin moisture, support barrier function, and increase the rate of keratinocyte production. Some studies also suggest this ingredient can protect our skin from oxidative stress.
Biologically, animals and some microorganisms use glycogen as an energy-storage molecule.
This ingredient is usually derived from marine or plant sources, but can sometimes come from animals. We recommend reaching out to the brand if you have questions about the source of their glycogen.
Learn more about Glycogen1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Â
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesÂ
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Carbomer is a high-molecular weight polymer of acrylic acid. It is used to form gels and thicken formulas.
Due to its large molecular size, carbomer has minimal skin penetration and is considered an inert ingredient.
A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.
Learn more about CarbomerChlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.
Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria.
Chlorphenesin is soluble in both water and glycerin.
Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.
Learn more about ChlorphenesinGlycosphingolipids are naturally found in the cell membranes of organisms. In animals, they are the major glycolipids found.
Glyolipids help ensure the stability of cell membranes. They also help with cellular recognition, such as allowing cells to form tissues in skin.
Peg-60 Hydrogenated Castor Oil comes from hydrogenated castor oil. It is a solubilizer and emulsifier.
As a solubilizer, it helps dissolve ingredients into a water-based version. It is also an emulsifer. Emulsifier help prevent oils and water from separating. Both these properties help create evenly-spread and uniform products.
Basically, Peg-60 Hydrogenated Castor Oil helps hold ingredients together.
Learn more about PEG-60 Hydrogenated Castor OilSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronatePotassium hydroxide is commonly known as caustic potash. It is used to fix the pH of a product or as a cleaning agent in soap. In cleansers, it is used for the saponification of oils.
Sapnification is the process of creating fatty acid metal salts from triglycerides and a strong base. During this process, Potassium Hydroxide is used up and is not present in the final product.
Using high concentrations of Potassium Hydroxide have shown to irritate the skin.
Learn more about Potassium HydroxideXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinThis ingredient is more commonly known as IPMP or Isopropyl Methylphenol. It is a preservative and has antimicrobial properties.
According to the EPA, this ingredient is allowed for use in cleansers, creams, powders, bath products, toothpaste, perfume, and more.
Glyceryl Acrylate/Acrylic Acid Copolymer is made up of glycerin and polyacrylic acid. It helps hydrate your skin as a humectant.
This ingredient forms a hydrogel that delivers moisturizing, water-based ingredients to the skin. It is also used to thicken a product and to give it a smooth texture.
Acrylic acid itself is toxic, but the polymer form (this ingredient) is too large to penetrate skin, making it non-toxic.
Learn more about Glyceryl Acrylate/Acrylic Acid CopolymerPVM/MA Copolymer is a synthetic and high-molecular weight polymer. It is used to create a flexible film that helps ingredients "stick together" on hair or skin. It also helps reduce static, help emulsions behave, and tweaks the thickness and flow of a product.
You'll most likely find this ingredient in hair styling products because that film is what helps styles last.
Sodium Lauroyl Lactylate is the lauric acid sodium salt of lactyl lactate.
Sodium Lauroyl Lactylate is an emulsifier and surfactant.
Emulsifiers help stabilize a product. They do this by preventing ingredients from separating, such as oils and water which do not mix naturally. Surfactants reduce surface tension, making it easier to rinse pollutants off skin.
Due to its relation to lauric acid, it may provide antimicrobial benefits.
Learn more about Sodium Lauroyl LactylateThis ingredient is the magnesium salt of PCA (Pyrrolidone Carboxylic Acid). It is a great skin hydrator for the top layers of skin.
PCA is a natural humectant, meaning it draws water from the air to your outer layer of skin.
One study found magnesium ions improved skin hydration in the outer layer of skin, or the stratum corneum. However, it did not improve TEWL, or the transepidermal water loss. The TEWL is an indicator of how healthy your skin barrier function is. This study primarily looked at healthy skin with intact skin barrier.
Learn more about Magnesium PCASodium Lactate is the sodium salt of lactic acid, an AHA. It is a humectant and sometimes used to adjust the pH of a product.
This ingredient is part of our skin's NMF, or natural moisturizing factor. Our NMF is essential for the hydration of our top skin layers and plasticity of skin. NMF also influences our skin's natural acid mantle and pH, which protects our skin from harmful bacteria.
High percentages of Sodium Lactate can have an exfoliating effect.
Fun fact: Sodium Lactate is produced from fermented sugar.
Learn more about Sodium LactateCopper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.
It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.
While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.
Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesnât turn soft, barely-visible facial hairs into thick, dark ones.
Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isnât backed by large-scale studies.
Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.
For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.
After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.
While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.
Read more about other common types of peptides here:
Learn more about Copper Tripeptide-1Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Learn more about Ceramide NPSerine is a non-essential amino acid (your body makes it on its own!). It is a major player in your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Serine is one of your NMF's most abundant components that works as a skin-identical humectant. Its hydroxyl group grabs onto water molecules to boost hydration without any heaviness or occlusion.
Research on a hydrogel with serine confirmed this serine got delivered to your stratum corneum and demonstrated enhanced skin moisturization.
Interestingly serine also helps your skin produce filaggrin, a protein that keeps your skin barrier strong and used to create collagen.
Learn more about SerineSucrose is a natural sugar found in fruits, vegetables, and nuts. It is the main constituent of white sugar.
In skincare, sucrose is a humectant and can be a mild exfoliant.
Sucrose is hydrophilic, meaning it attracts water. This makes it an effective humectant and helps hydrate the skin.
Studies show sugars may worsen acne-prone skin due to it disrupting the skin's natural biome. We recommend speaking with a professional if you have any concerns.
In some products such as body scrubs, sucrose is used as an gentle exfoliant.
The term 'sucrose' comes from the french word for sugar, 'sucre'.
Learn more about SucroseUrea is also called carbamide and is the diamide of carbonic acid. In cosmetics, urea is used to hydrate the skin. It also provides exfoliation in higher concentrations.
As a humectant, urea helps draw moisture from the air and from deep within the skin. This helps hydrate your skin. Studies show urea is an effective moisturizer for dry skin conditions. 40% urea is typical in medications for treating eczema and other skin conditions.
Urea has the strongest exfoliation effect in concentrations higher than 10%. It is a keratolytic agent, meaning it breaks down the keratin protein in the top layer of skin. This helps remove dead skin cells and flaking skin.
In medicine, urea has been shown to help increase the potency of other ingredients, such as fungal treatments.
Humans and animals use urea to metabolize nitrogen-containing compounds. Urea is highly soluble in water. Once dissolved, it is neither acidic nor alkaline.
Urea is actually one of the more well-studied and well-supported ingredients out there if you have eczema.
Clinical trials have shown that urea creams in the 5 - 10% range can:
Higher concentrations (20 -30%) can also help with thickened, scaly patches but is also more likely to sting on active flares.
Skip urea if you have rosacea. The AAD (American Academy of Dermatology) lists it alongside alcohol, menthol, and fragrance as a potential irritant for rosacea-prone skin. Urea's keratolytic and penetration-enhancing properties can trigger stinging, burning, and redness.
As always, your skin is unique, so definitely check in with your dermatologist.
Learn more about UreaGlycine is the smallest amino acid and a key building block of collagen. It's part if your skin's Natural Moisturizing Factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
A study from 2022 found that an amino acid complex featuring taurine, arginine, and glycine significantly reduced skin irritation, improved redness, and accelerated the skin repair process.
Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function.
You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has.
The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function.
Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration.
Learn more about Ceramide APCholesterol is a lipid that is naturally found in human skin and is one of the three key components of your skin barrier. In skincare, it is an emollient and barrier-repairing ingredient.
It works by fitting directly into the lipid layers of skin to help restore structure and reduce transepidermal water loss (TEWL).
This is a great ingredient for dry, compromised, or aging skin; our skin starts to produce less cholesterol with age.
Research shows cholesterol works best in combination with ceramides and fatty acids, the other two major components in your skin barrier.
Cholesterol is also a well-establish penetration enhancer and can help other actives absorb more effectively.
Cosmetic-grade cholesterol is usually derived from lanolin but plant and synthetic options also exist. We recommend reaching out to the brand if you have questions about their source of cholesterol.
Learn more about CholesterolPhytosphingosine is a phospholipid naturally found in our skin as a building block for ceramides.. It helps moisturize, soothe, and protect skin.
Phytosphingosine contributes to your skin's natural moisturizing factor (NMF). The NMF is responsible for hydration, a strong barrier, and plasticity. Our NMF decreases with age. Increasing NMF leads to more healthy and hydrated skin.
Studies show products formulated with NMF ingredients help strengthen our skin's barrier. Having a healthy skin barrier reduces irritation and increases hydration. Our skin barrier is responsible for having plump and firm skin. It also helps protect our skin against infection, allergies, and inflammation.
Fun fact: Phytosphingosine is abundant in plants and fungi.
More ingredients that help boost collagen in skin:
Learn more about PhytosphingosineCalcium chloride is a white, odorless, crystalline solid. It is an astringent and can be used to change the viscosity of products.
This ingredient is highly soluble in water, acetic acid, and ethanol.
There are many forms of this ingredient, including monohydrate, dihydrate, tetrahydrate, and hexahydrate.
Learn more about Calcium ChlorideWe don't have a description for Ornithine yet.
Sea salt has abrasive or exfoliation properties. It can sensitize and dry out the skin.
Alanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.
Magnesium chloride is a mineral salt made from magnesium and chloride. It is mainly used to control product stability and texture in cosmetics.
This ingredient can also play a role in soothing the skin and supporting normal skin function.
Magnesium chloride is water-soluble, generally well tolerated, and does not act as a strong âactiveâ ingredient on its own.
Learn more about Magnesium ChlorideThreonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.
Our skin uses threonine for creating collagen and elastin. Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.
Histidine is a semi-essential amino acid used by our bodies to create protein. It has humectant and skin conditioning properties.
Our bodies use histidine to create filaggrin - filaggrin is a structural protein that the skin uses in maintaining skin barrier.
One study found histidine and carnosine to be a dynamic duo for your skin:
Oral histidine has also been found to help with filaggrin-deficit skin disorders such as atopic dermatitis.
Why is it considered a semi-essential amino acid? This is because adults are able to create it but children must get it from their diet.
Learn more about HistidineAspartic Acid is an amino acid that our bodies produce naturally. It is an antioxidant.
Our body uses Aspartic Acid to help build collagen and elastin. It also plays a role in hydrating skin.
Valine is an essential amino acid. It is used by our bodies for tissue repair and muscle growth.
An essential amino acid is one in which our bodies cannot naturally produce so we must get them through diet. Foods such as eggs, dairy, red meat, and fish contain valine.
This ingredient can either be derived from an animal product or be synthetically created.
Learn more about ValineProline is a non-essential amino acid, meaning your body can make it on its own. In skincare, it is a skin conditioning ingredient that keeps skin soft and hydrated.
It makes up about 23% of the collagen molecule (collagen is the protein responsible for keeping your skin firm) and is involved in your skin's natural hyaluronic acid production. When applied topically, proline can penetrate the skin fairly well due to its small molecular size.
Reviews of this ingredient have found it to be neither a dermal irritant nor a sensitizer.
Fun fact: Proline can be found in protein-rich foods like meat, fish, eggs, and dairy.
Learn more about ProlineDipotassium Phosphate is an inorganic salt. This just means it has a different structure than organic salts. It is a stabilizing and pH adjusting ingredient.
This ingredient is soluble in water.
Lysine is an essential amino acid (your body cannot make it on its own). It has skin conditioning properties and one of the key players in collagen synthesis.
When your body creates collagen, lysine is basically the glue that holds everything together. It helps collagen fibers lock into each other and stay strong, with vitamin C being its trusty sidekick. Without enough lysine, this glue gets flimsy and less firm, resulting in less bouncy skin.
In skincare, lysine is mostly there to help keep your skin moisturized. It carries water through your skin's layers so everything stays plump.
So will putting lysine on your face create bouncier skin?
It's hard to say; most of the exciting collagen research on lysine comes from oral supplements or lab studies on mice. Further research is needed to truly understand what role topical lysine plays in skincare and your skin.
However, there's no harm in adding lysine to your routine as a supportive and hydrating ingredient.
Learn more about LysineWe don't have a description for Leucine yet.
Tyrosine is one of the amino acids used to create protein. It plays a role in melanin production.
A study from 2012 found tyrosine to show promising results in restoring skin volume.
Isoleucine is an amino acid that helps reinforce our skin barrier. This amino acid plays a role in creating protein for the body.
Fun fact: Isoleucine is found in meat, fish, dairy, legumes, and nuts.
We don't have a description for Magnesium Citrate yet.
We don't have a description for Glucosamine Hcl yet.
Glutamic Acid is an amino acid that is found in all living organisms. Our bodies use this to help nerve cells in the brain communicate with other cells.
In cosmetics, glutamic acid is a famous humectant. It draws water from the air to your skin, keeping your skin hydrated (like hyaluronic acid).
An in-vitro study from 2024 found glutamic acid to play a role in inhibiting inflammation and thus a potential skin-soothing ingredient.
Other studies show it to be have potential wound healing, skin barrier repair, and hair growth properties.
Glutamic acid has poor solubility in water and other solvents.
Learn more about Glutamic AcidPhenylalanine is an amino acid. It is a skin soothing and hydrating ingredient. Amino acids play a crucial role in wound healing and skin hydration.
This ingredient is also used to help even out skin tone due to its ability to disrupt the melanin production process.
Two structures of phenylalanine exist: L-phenylalanine and D-phenylalanine. L-phenylalanine is essential, this means our bodies cannot produce it naturally and we must get it from foods. Our bodies convert D-phenylalanine to neurotransmitters, and D-phenylalanine is found in our bodies naturally.
Some foods that contain L-phenylalanine include eggs, soybeans, beef, milk.
Learn more about PhenylalanineArginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.
Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.
One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.
Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.
Learn more about ArginineWe don't have a description for 1-Methylhydantoin-2-Imide yet.
Asparagine is one building block of all proteins in our body. It is an antioxidant and may help with anti-aging.
Antioxidants help fight free-radicals, or molecules that may damage our skin cells.
We don't have a description for Citrulline yet.
We don't have a description for Uric Acid yet.
Methionine is an essential amino acid. It is a conditioning agent and commonly found in both skin and hair products.
This amino acid is a precursor to glutathione, a powerful antioxidant.
Fun fact: Methionine can be found in meat, fish, and dairy. It cannot be naturally produce and requires dietary intake.
Learn more about MethionineTaurine is an amino acid that is found in human skin as an osmolyte. An osmolyte is a small molecule that cells use to hold onto water and stay comfortable under stressful conditions.
In skin cell studies, taurine accumulation helps cells maintain hydration in low-humidity environments. Some dermatology research on osmolytes also link taurine to barrier support. Research also suggests that osomolyte systems can be disrupted in photoaged skin.
One animal study reported tropical taurine improved barrier function and collagen signaling, while another one found oral taurine can lessen UVB-related damage. It is important to note that evidence for taurine in skincare is mostly preclinical, meaning further studies are needed.
Learn more about TaurineWe don't have a description for Tryptophan yet.
Cysteine is an amino acid found in our bodies. It becomes an antioxidant when converted into gluthatione.
Once it becomes gluthatione, it prevents oxidative damage to parts of our cell. Gluthatione has also been shown to protect our skin from UV-B induced damage.
Glutamine is an amino acid (a small building block your body uses to make proteins). It has skin conditioning properties and helps skin feel comfortable.
Think of glutamine as a quiet support player in your skincare. Your skinâs outer layer (stratum corneum) needs two things to stay healthy: a strong barrier and enough moisture.
Part of what helps hold water in the skin is something called Natural Moisturizing Factors (NMF). These include amino acids or the same building blocks that make up proteins in your body.
Since glutamine is an amino acid, it falls into the âbarrier-friendly, skin-conditioningâ category. Thatâs why youâll usually find it in hydrating and soothing formulas.
There's some experimental evidence that glutamine can calm inflammation-related skin reactions when applied topically in a contact-dermatitis model. However, it's not the same as a proven eczema fix.
Learn more about GlutamineCeramide EOP is formally known as Ceramide 1.
It is naturally found in skin and part of the intercellular "mortar" holding everything together in your outermost layer.
EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base.
What makes Ceramide EOP special is its ultra-long fatty acid chain; this unique structure allows it to bridge the lipid layers in your skin barrier to prevent water loss (something no other ceramide can do).
Low levels of Ceramide EOP have been found in people with eczema and psoriasis.
Using it together with other ceramides, cholesterol, and linoleic acid have been shown to meaningfully improve hydration and reduce water loss.
In one clinical study, a regimen using Ceramide EOP, NP, and AP led to significant symptom improvements in patients with eczema, psoriasis, and dry skin in just 4 weeks.
You'll usually see concentrations between 0.1-0.5% in formulations. Overall, this is a well-tolerated and safe ingredient for cosmetic use.
Learn more about Ceramide EOPReviews
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Dr. Wu is a Taiwanese brand
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