Cultured Biomecare Biome One Mask
A sheet mask with 26 ingredients, including AHA and azelaic acid.
This smoothing sheet mask is formulated around Lactic Acid and Saccharomyces Ferment Filtrate to refine skin texture and brighten dull-looking skin.
Worth noting
Contains Benzyl Alcohol, an EU-listed fragrance allergen.
We independently verify ingredients, backed by peer-reviewed research. Suggest an update.
What's inside
Ingredients List
Water
Skin ConditioningGlycerin
HumectantLactic Acid
BufferingPropanediol
SolventPentylene Glycol
Skin ConditioningSodium Lactate
BufferingSaccharomyces Ferment Filtrate
HumectantSuccinic Acid
BufferingInulin
Skin ConditioningLactococcus Ferment Lysate
Skin ConditioningPotassium Azeloyl Diglycinate
Skin ConditioningSaccharomyces/Xylinum/Black Tea Ferment
Skin ConditioningMalic Acid
BufferingAlbatrellus Confluens Extract
HumectantCellulose Gum
Emulsion StabilisingXanthan Gum
EmulsifyingCellulose
AbsorbentFructose
HumectantGlucose
HumectantSodium Chloride
MaskingCaramel
Cosmetic ColorantHydroxyacetophenone
AntioxidantBenzyl Alcohol
PerfumingSodium Benzoate
MaskingPotassium Sorbate
PreservativeDehydroacetic Acid
PreservativeWater, Glycerin, Lactic Acid, Propanediol, Pentylene Glycol, Sodium Lactate, Saccharomyces Ferment Filtrate, Succinic Acid, Inulin, Lactococcus Ferment Lysate, Potassium Azeloyl Diglycinate, Saccharomyces/Xylinum/Black Tea Ferment, Malic Acid, Albatrellus Confluens Extract, Cellulose Gum, Xanthan Gum, Cellulose, Fructose, Glucose, Sodium Chloride, Caramel, Hydroxyacetophenone, Benzyl Alcohol, Sodium Benzoate, Potassium Sorbate, Dehydroacetic Acid
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinLactic Acid is another well-loved alpha hydroxy acid (AHA). It is gentler than glycolic acid but still highly effective.
Its main role is to exfoliate the surface of the skin by loosening the “glue” that holds dead skin cells together. Shedding those old cells leads to smoother, softer, and more even-toned skin.
Because lactic acid molecules are larger than glycolic acid, they don’t penetrate as deeply. This means they’re less likely to sting or irritate, making it a great choice for beginners or those with sensitive skin.
Like glycolic acid, it can:
Lactic acid also acts as a humectant (like hyaluronic acid). It can draw water into the skin to improve hydration and also plays a role in the skin's natural moisturizing factor (NMF) in the form of sodium lactate.
Studies show it can boost ceramide production to strengthen the skin barrier and even help balance the skin’s microbiome.
To get results, choose products with a pH between 3-4.
Lower strengths (5-12%) focus on surface exfoliation; higher strengths (12% and up) can reach deeper in the dermis (deeper, supportive layer) to improve skin texture and firmness over time.
Though it was originally derived from milk, most modern lactic acid used in skincare is vegan. It is made through non-dairy fermentation to create a bio-identical and stable form suitable for all formulations.
When lactic acid shows up near the end of an ingredient list, it usually means the brand added just a tiny amount to adjust the product’s pH.
Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.
Lactic acid is truly a gentle multitasker: it exfoliates, hydrates, strengthens, and brightens. It's a great ingredient for giving your skin a smooth, glowing, and healthy look without the harshness of stronger acids.
Read more about some other popular AHA's here:
Learn more about Lactic AcidPropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolPentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolSodium Lactate is the sodium salt of lactic acid, an AHA. It is a humectant and sometimes used to adjust the pH of a product.
This ingredient is part of our skin's NMF, or natural moisturizing factor. Our NMF is essential for the hydration of our top skin layers and plasticity of skin. NMF also influences our skin's natural acid mantle and pH, which protects our skin from harmful bacteria.
High percentages of Sodium Lactate can have an exfoliating effect.
Fun fact: Sodium Lactate is produced from fermented sugar.
Learn more about Sodium LactateSaccharomyces Ferment Filtrate is the watery, nutrient-rich liquid left over after you ferment a yeast (genus Saccharomyces).
The yeast cells themselves are filtered out so you're getting the "broth" of skin-friendly molecules: amino acids, peptides, minerals, vitamins, organic acids, and beta-glucan.
Evidence-wise, its relatives (like Galactomyces) are the ones with the most published lab work. Keratinocyte studies show these ferments can boost barrier-related markers. This ingredient is generally assumed to behave similarly thanks to its overlapping composition.
This ingredient may not be fungal acne safe because its a fermentation filtrate. The exact composition is batch-variable and can include fatty acids and lipids byproducts.
Learn more about Saccharomyces Ferment FiltrateSuccinic acid is an odorless white powder. It is naturally found in our bodies but can also be derived from living organisms.
Succinic acid is water-soluble. The pH level of this ingredient is between 4.2 and 5.6.
While succinic acid posesses antimicrobial, antioxidant, and anti-inflammatory properties, these properties have not been studied in skincare products.
Fun fact: Succinic acid was known as the 'spirit of amber' in the past. This is because it used to be derived from distilling amber.
Learn more about Succinic AcidInulin is a polysaccharide (carbohydrate) with prebiotic and antioxidant properties.
The majority of inulin is extracted from chicory, but can also be obtained from other plants such as garlic, onion, asparagus, and sugarcane.
Studies show inulin may help with controlling your skin's natural microbiota when applied topically.
The antioxidant potential of inulin varies depending on the source.
Learn more about InulinLactococcus Ferment Lysate is a postbiotic created by fermenting Lactoccus lactis, a type of bacteria more commonly used to create Lactic acid.
Postbiotics are inactive molecules produced by probiotic bacteria that provide skin benefits.
This ingredient offers promising benefits, but it is relatively new and more evidence is needed to prove its efficacy. The manufacturer claims this ingredient:
A study from 2022 found this ingredient helped protect skin against damaged from UV exposure (though this should not replace your sunscreen!).
The lysate in the ingredient name refers to a fluid that forms from breaking down the cell membrane.
Learn more about Lactococcus Ferment LysatePotassium Azeloyl Diglycinate (PAD) comes from the condensation of azelaic acid mixed with glycine.
This ingredient has similar properties to azelaic acid; it can help reduce sebum production and soothe skin. PAD also inhibits tyrosinase activity to help brighten skin. Tyrosinase is an enzyme that controls melanin production.
A study from 2023 found 5% PAD combined with nicotinamide (a form of niacin) effectively reduced melanin production after 6 weeks.
Several studies from the 2010's also show PAD to be effective in alleviating symptoms of Rosacea.
Though this ingredient is considered a gentle active, higher amounts may result in irritation.
Unlike azelaic acid, this ingredient is water-soluble. This property makes it easier to formulate into skincare products.
Learn more about Potassium Azeloyl DiglycinateThis combination of bacteria + black tea + fermentation = kombucha.
According to a manufacturer, this ingredient helps boost radiance, smoothness, and thickens skin.
You can read about the skin benefits of the individual parts here:
Saccharomyces
Black tea
Malic Acid is an acid with both AHA and BHA properties, but is considered an AHA because its AHA properties are stronger.
It can be naturally found in unripe fruit and especially apples (its name from the latin word "malum", meaning apple!).
Like other AHAs, malic acid gently removes the top layer of dead skin cells to reveal smoother, brighter skin underneath.
Though it’s considered milder and less potent than glycolic or lactic acid, it can help improve:
Due to its larger molecular structure, it penetrates the skin more slowly and is often used in combination with other AHAs to enhance their overall effectiveness.
Malic acid often plays a role in balancing a product’s pH and is usually included in small amounts (around 1-2%) as a supporting exfoliant.
As with all exfoliating acids, you should wear sunscreen daily when using malic acid to protect your newly resurfaced skin.
Fun fact: Malic acid is the compound responsible for the tart flavor of apples and other sour fruits.
While research on malic acid is limited compared to glycolic or lactic acid, it’s still a safe and mild exfoliant.
Read more about some other popular AHA's here:
Learn more about Malic AcidAlbatrellus Confluens Extract is from a mushroom from Finland, known as the Nothern Truffle (this mushroom is edible!). It has skin soothing and antioxidant properties.
This ingredient decreases redness and irritation by blocking the signals that trigger inflammation.
Cellulose Gum is a water-soluble polymer that comes from cellulose. It is used to change the texture of a product and to help stabilize emulsions.
As an emulsifier, cellulose gum specifically thicken the texture of water-based products.
This ingredient is considered hypoallergenic and non-toxic. Cellulose Gum can be found in cosmetics, food, and other household goods such as paper products.
Learn more about Cellulose GumXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumCellulose is the main component of plant cell walls. It is used as an emulsifier, absorbent, and texture enhancer.
This ingredient has many functions:
Fun fact: Cellulose is the most abundant form of organic polymer on Earth.
Learn more about CelluloseGlucose is a simple sugar (a monosaccharide). In skincare, it is mostly a humectant and skin conditioning agent.
Mechanistically, it has multiple hydroxyl groups that hydrogen-bond to water. This pulls moisture into the upper layers of skin to keep the surface soft and hydrated.
It's worth knowing sugars are already a natural component of the skin's NMF (natural moisturizing factor) so it's a molecule that your stratum corneum is well-acquainted with.
Just so you know, glucose is hydrophilic (water-loving) and the stratum corneum is a strong barrier to hydrophilic compounds. This just means penetration is slow and most of the action is happening on the surface.
Gram-to-gram, glucose is not as efficient as a humectant as glycerin. This is why you'll likely see glycose paired with stronger humectants for a bigger hydration payoff.
In skincare, glucose is typically derived from corn or other starch sources.
Learn more about GlucoseChances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt. This ingredient has many purposes in skincare: thickener, emulsifier, and exfoliator.
You'll most likely find this ingredient in cleansers where it is used to create a gel-like texture. As an emulsifier, it also prevents ingredients from separating.
You might see people debate whether Sodium Chloride is comedogenic, but there actually haven't been any comedogenic tests done on it. Either way, the overall formulation of a product matters a lot more than any single ingredient.
You might see this ingredient used in scrubs as a primary exfoliating ingredient.
Learn more about Sodium ChlorideWe don't have a description for Caramel yet.
Hydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster.
As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress.
Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol.
This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency.
You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase.
Safety testing was done at concentrations like 0.05% in SPF products and 0.5% in a Human Repeated Insult Patch Test. The safety evidence is assuring; this ingredient is safe for cosmetics in current use and also holds safety status as a food flavoring as well.
An honest caveat: the "soothing" and "anti-inflammatory" claims come mostly from supplier marketing rather than published clinical trials. The Cosmetic Ingredient Review's own literature search found no useful efficacy studies on this ingredient.
So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced.
Overall, this is a well-tolerated, low-irritation multitasker that quietly helps a formula stay fresh and stable.
Learn more about HydroxyacetophenoneBenzyl Alcohol is an aromatic alcohol with several roles: it's a preservative, solvent, and mild fragrance component with a floral scent.
This ingredient has been deemed safe for use in cosmetic formulations at concentrations up to 5%, and up to 10% in hair dyes. You'll typically see 0.5-2% in most rinse-off or leave-on products.
As a preservative, it works by disrupting the membrane of microbial proteins. This helps keep bacteria and fungi from growing in your products.
The sensitization picture is actually quite assuring as well:of nearly 71,000 patients patch tested with benzyl alcohol, only 0.21% showed a positive reaction with most of them being weakly positive.
This led researchers to conclude that benzyl alcohol cannot be regarded as a significant contact allergen.
It is worth noting this ingredient is classified as one of the EU's regulated fragrance allergens and restricted to 1% in finished products.
Labels must also declare it in concentrations above 0.001% in leave-on products and 0.01% in rinse-off products.
At concentrations around 5%, localized redness and itching can appear as a direct irritant response and not as a true allergic reaction.
Learn more about Benzyl AlcoholSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoatePotassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Learn more about Potassium SorbateDehydroacetic Acid is a synthetic preservative that keeps your products safe from microbes.
As an organic acid, it penetrates microbial cell walls and disrupts cellular metabolism. This makes it effective against bacteria, yeast, and mold.
It is effective at low concentrations (<0.6%). Clinical studies have found it to be non-irritating, non-sensitizing, and non-photosensitizing.
Learn more about Dehydroacetic AcidReviews
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Where it's from
Cultured Biomecare is a British brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated December 28, 2023 • Added by tsmeu