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Updated on June 28, 2024

Overview

What they are

These products are both cruelty-free and reef safe serums. They have a total of 6 ingredients in common

Cool Features

They both contain niacinamide

Suited For

They're both likely to be good for fighting acne, dry skin, brightening skin, sensitive skin, oily skin, reducing pores and dark spots

Free From

They both do not contain any harsh alcohols, common allergens, oils, parabens or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Regimen Lab Level Serum
Regimen Lab Level Serum
Serum
Canadian Brand Canada
Dr. Idriss The Depuffer
Dr. Idriss The Depuffer
Serum
American Brand United States

Ingredient Info

Click any item below to learn more and see relevant ingredients

Regimen Lab Level Serum 23 ingredients

Dr. Idriss The Depuffer 24 ingredients

At a glance

Click on any of the items below to learn more

Regimen Lab Level Serum 23 ingredients

Dr. Idriss The Depuffer 24 ingredients

Notable Ingredients

Benefits

Notable Ingredients

Benefits

Ingredients Side-by-side

found in both products
Level Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Propanediol Solvent

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Betaine Humectant, Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon
3 Benefits

Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.

Dimethyl Isosorbide Solvent

Dimethyl Isosorbide is a solvent and helps deliver actives into your skin. It is created from sorbitol.

Tranexamic Acid Astringent, Skin Conditioning
Good for Dark Spots Icon
Good for Dark SpotsGood for Dark Spots Icon

Tranexamic Acid is best used for treating hyperpigmentation, discoloration, and melasma. It can also help build a stronger skin barrier.

Acetyl Glucosamine Skin Conditioning
Vitamin C Icon
Vitamin CVitamin C Icon

Acetyl Glucosamine is an antioxidant and humectant. It is a form of Vitamin C.

Alpha-Arbutin Antioxidant, Bleaching, Skin Conditioning
Antioxidant IconGood for Dark Spots IconGood for Scar Healing Icon
AntioxidantAntioxidant Icon 2 Benefits

Alpha-Arbutin is made from hydroquinone and glucose. It may also be derived from the fermentation of soybeans.

Undecylenoyl Phenylalanine Skin Conditioning

We don't have a description for Undecylenoyl Phenylalanine.

Unknown Full details ->
Glycyrrhiza Glabra Root Extract Bleaching, Emollient, Skin Conditioning
Good for Dark Spots Icon
Good for Dark SpotsGood for Dark Spots Icon

Glycyrrhiza Glabra Root Extract is an extract of the roots of Licorice. It has been found to have several benefits such as skin hydrating, conditioning, and soothing.

Dipotassium Glycyrrhizate Humectant, Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon
3 Benefits

Dipotassium Glycyrrhizate comes from licorice root.

Tetrahydrodiferuloylmethane Antioxidant
Antioxidant Icon
AntioxidantAntioxidant Icon

Tetrahydrodiferuloylmethane is an antioxidant.

Unknown Full details ->
Hexylresorcinol Antimicrobial

Another popular name for this ingredient is Synovea HR. This ingredient is a skin lightener and antioxidant.

Dimethylmethoxy Chromanol Antioxidant
Antioxidant Icon
AntioxidantAntioxidant Icon

Dimethylmethoxy Chromanol is an antioxidant.

Unknown Full details ->
Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Lecithin Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids. These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients scuh as sunflower.

Disliked Full details ->
Sclerotium Gum Emulsion Stabilising, Skin Conditioning

Sclerotium Gum is a polysaccharide gum made by the fungus, Sclerotium rolfssii. It is similar to xanthan gum.

Disliked Full details ->
Pullulan

We don't have a description for Pullulan.

Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

The Depuffer
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Pentylene Glycol Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Propanediol Solvent

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Emulsion Stabilising

This is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.

Disliked Full details ->
Squalane Emollient, Skin Conditioning
1 / 0 Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

1 Com. / 0 Irr.
Arnica Montana Flower Extract Masking, Perfuming, Skin Conditioning
Fragrance Icon
FragranceFragrance Icon

Arnica Montana Flower is more commonly known as Wolf's Bane. While this flower has been used in traditional medicine, its skin benefits are in question.

Centella Asiatica Leaf Extract Skin Conditioning
Helps reduce Skin Redness Icon
Helps reduce Skin RednessHelps reduce Skin Redness Icon

Centella Asiatica Leaf Extract comes from the leaves of an herb plant native to Southeast Asia. Centella Asiatica is rich in antioxidants and amino acids. It can help reduce irritation and soothe the skin.

Fraxinus Excelsior Bark Extract Skin Conditioning

We don't have a description for Fraxinus Excelsior Bark Extract.

Unknown Full details ->
Agastache Mexicana Flower/Leaf/Stem Extract Skin Conditioning, Skin Protecting

Agastache Mexicana is a shrub from North America. All parts of this shrub contain antioxidants.

Unknown Full details ->
Avena Sativa Kernel Extract Abrasive, Antioxidant, Emollient
Exfoliant IconAntioxidant IconHelps hydrate Dry Skin Icon
ExfoliantExfoliant Icon AntioxidantAntioxidant Icon Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Avena Sativa Kernel Extract is is derived from colloidal oatmeal. Besides being a healthy breakfast, oats have many benefits in skincare too.

Camellia Sinensis Leaf Extract Antimicrobial, Antioxidant, Astringent
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconHelps fight Acne Icon
AntioxidantAntioxidant Icon 5 Benefits

Camellia Sinensis Leaf Extract is derived from the leaves of the tea plant. Black tea, green tea, and oolong tea are all harvested from this plant.

Hydroxyphenyl Propamidobenzoic Acid Skin Conditioning

We don't have a description for Hydroxyphenyl Propamidobenzoic Acid.

Unknown Full details ->
Maltodextrin Absorbent, Emulsion Stabilising, Skin Conditioning

Maltodextrin is a polysaccharide. It is derived from starch such as rice, corn, wheat, or potato starch.

Dimethicone Crosspolymer Emulsion Stabilising

Dimethicone Crosspolymer is a silicone created by modifying dimethicone with hydrocarbon side chains. Due to its large size, it does not penetrate skin. It is considered non-occlusive.

Very Disliked Full details ->
Silanetriol

We don't have a description for Silanetriol.

Unknown Full details ->
Sorbitan Isostearate Emulsifying
1-2 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Sorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.

1-2 Com. / 0 Irr.
Very Disliked Full details ->
Polysorbate 60 Emulsifying
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.

Very Disliked Full details ->
Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Hexylene Glycol Emulsifying, Skin Conditioning, Solvent
0-2 / 0-1

Hexylene Glycol is a surfactant. Glycols are a class of alcohols. Hexylene Glycol is a surfactant and emulsifier.

0-2 Com. / 0-1 Irr.
Disliked Full details ->
Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Solvent
Liked

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

Propanediol is not likely to cause sensitivity and considered safe to use.

It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Smoothing
Loved

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide
Emollient, Humectant, Skin Conditioning
Liked

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
Preservative
Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Skin Conditioning
Mixed

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Ingredient Ratings

Here's what our community thinks of the ingredients in these two products.

Level Serum
12
3
5
3
liked
mixed
disliked
not rated
The Depuffer
11
3
6
4
liked
mixed
disliked
not rated

When to use

Regimen Lab Level Serum 23 ingredients

Dr. Idriss The Depuffer 24 ingredients

70 Routines
50% use in am
49% use in pm
94% use every day
When to use See routines that use it ->
9 Routines
78% use in am
22% use in pm
89% use every day

Reviews

Here's what our community thinks

Regimen Lab Level Serum 23 ingredients

4.8 /5
from 4 ratings
Works Well (1)
apricottle's avatar

apricottle

2 years ago · Skin
Review

PIE/PIH Killer
A lot of my post-acne marks have faded significantly after using this. Good texture, no pilling. No discernible smell.

naevis's avatar

naevis

18 days ago · Sensitive Skin
Review

Dr. Idriss The Depuffer 24 ingredients

The Depuffer hasn't been rated yet.
Rate it now