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Updated on October 03, 2023

Overview

Cool Features

They both contain niacinamide

Suited For

They're both likely to be good for fighting acne, dry skin, brightening skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates

What's Inside

They both contain silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Olay Regenerist Retinol 24 Night Facial Moisturizer
La Roche-Posay Effaclar Duo+M
La Roche-Posay Effaclar Duo+M
Facial Treatment
French Brand France

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Regenerist Retinol 24 Night Facial Moisturizer
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0 Silicon Icon
SiliconSilicon Icon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

1 Com. / 0 Irr.
Very Disliked Full details ->
Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Tapioca Starch

We don't have a description for Tapioca Starch.

Disliked Full details ->
Dimethicone Crosspolymer Emulsion Stabilising

Dimethicone Crosspolymer is a silicone created by modifying dimethicone with hydrocarbon side chains. Due to its large size, it does not penetrate skin. It is considered non-occlusive.

Very Disliked Full details ->
Retinol Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconCan worsen Dry Skin IconMay cause irritation IconMay worsen Eczema Icon
RetinoidRetinoid Icon 8 Benefits 3 Concerns

Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.

Retinyl Propionate Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconCan worsen Dry Skin IconMay cause irritation Icon
RetinoidRetinoid Icon 7 Benefits 2 Concerns

Retinyl Propionate is a retinoid. Retinoids are the gold-standard class of anti-aging ingredients.

Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Palmitoyl Pentapeptide-4 Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

You might know this ingredients as Matrixyl. It is a peptide.

Polyacrylamide

Polyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.

Disliked Full details ->
C13-14 Isoparaffin Emollient, Solvent
May worsen Oily Skin IconNot safe for Fungal Acne Icon
2 Concerns

C13-14 Isoparaffin is created from petroleum-based mineral oils. It is an emollient and helps thicken a product.

Very Disliked Full details ->
DMDM Hydantoin Preservative
Preservative IconMay cause irritation IconMay worsen Eczema Icon
PreservativePreservative Icon 2 Concerns

DMDM Hydantoin has antimicrobial and antifungal properties. It is a preservative that works by slowly releasing formaldehyde over time.

Very Disliked Full details ->
Polysorbate 20 Emulsifying
0 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

0 Com. / 0 Irr.
Very Disliked Full details ->
Laureth-4 Emulsifying, Masking
5 / 4 May worsen Oily Skin Icon
May worsen Oily SkinMay worsen Oily Skin Icon

Laureth-4 is created by reacting ethylene oxide with Lauryl Alcohol. It is a surfactant and emulsifier.

5 Com. / 4 Irr.
Unknown Full details ->
Acrylates/C10-30 Alkyl Acrylate Crosspolymer Emulsion Stabilising

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products.

Disliked Full details ->
Laureth-7 Emulsifying

Laureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.

Disliked Full details ->
Dimethiconol Emollient, Moisturising

Dimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.

Disliked Full details ->
Polymethylsilsesquioxane
Silicon Icon
SiliconSilicon Icon

Polymethylsilsesquioxane is a silicone used as a film forming agent.

Disliked Full details ->
Aminomethyl Propanol Buffering

Aminomethyl Propanol is used to adjust the pH of products. It is also used as a base to create other organic compounds. Having a balanced pH is important for protecting your skin.

Titanium Dioxide Cosmetic Colorant, UV Absorber, UV Filter
0 / 0 Mineral UV Filter IconNon-Reef-Safe Icon
Mineral UV FilterMineral UV Filter Icon Non-Reef-SafeNon-Reef-Safe Icon

Titanium dioxide is known for its UVA and UVB protection properties. It is non-comedogenic and non-irritating. Titanium Dioxide is a physical sunscreen. Physical sunscreens reflect light and prevent it from reaching your skin.

0 Com. / 0 Irr.
Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Iodopropynyl Butylcarbamate Preservative
Preservative Icon
PreservativePreservative Icon

Iodopropynyl Butylcarbamate is a preservative.

Very Disliked Full details ->
Caprylyl Caprylate Emollient

This ingredient is an emollient and helps give products a dry but silky feel.

Unknown Full details ->
Aminopeptidase Skin Conditioning

We don't have a description for Aminopeptidase.

Unknown Full details ->
Effaclar Duo+M
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0 Silicon Icon
SiliconSilicon Icon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

1 Com. / 0 Irr.
Very Disliked Full details ->
Isocetyl Stearate Emollient, Skin Conditioning
0-1 / 0 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon
3 Concerns

Isocetyl Stearate is an ester of isocetyl alcohol and stearic acid.

0-1 Com. / 0 Irr.
Unknown Full details ->
Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Ammonium Polyacryloyldimethyl Taurate Emulsion Stabilising

Ammonium Polyacryloyldimethyl Taurate is a polymer made from ammonium salts. It helps add stability and texture to a product.

Oryza Sativa Starch Absorbent

Oryza Sativa Starch is an absorbent and used to mattify the skin. It is a natural carbohydrate and the main component of rice. A more common name for this ingredient is 'rice starch'.

Punica Granatum Pericarp Extract Skin Conditioning

We don't have a description for Punica Granatum Pericarp Extract.

Unknown Full details ->
Potassium Cetyl Phosphate Emulsifying

Potassium Cetyl Phosphate is the potassium salt of a mixture. This mixture consists of the esters from phosphoricacid and cetyl alcohol.

Sorbitan Oleate Emulsifying
3 / 0 Bad for Acne Prone Skin IconNot safe for Fungal Acne Icon
2 Concerns

Sorbitan Oleate is created from compounds in oleic acid and sorbitol. It is used to stabilize a product by preventing ingredients from separating.

3 Com. / 0 Irr.
Very Disliked Full details ->
Zinc PCA Humectant, Skin Conditioning
Good for Scar Healing IconHelps fight Acne Icon
2 Benefits

Zinc PCA (or "zinc salt") differs slightly from zinc itself. PCA stands for pyrrolidone carboxylic acid. However, Zinc PCA comes from zinc.

Glyceryl Stearate Se Emulsifying
3 / 2 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Glyceryl Stearate Se is a self-emulsifying (SE) form of glyceryl stearate. Self-emusifying means this ingredient automatically blends with water. It is an emulsifier, emollient, and cleansing agent.

3 Com. / 2 Irr.
Very Disliked Full details ->
Isohexadecane Emollient, Skin Conditioning, Solvent

Isohexadecane is added to enhance texture, emulsify, and to help cleanse. It is an isoparrafin. It is a component of petrolatum.

Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

Myristyl Myristate Emollient, Skin Conditioning
0-5 / 2 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon
3 Concerns

Myristyl Myristate is created from the fatty acids of myristyl alcohol and myristic acid. In skincare, it is an emollient and texture enhancer.

0-5 Com. / 2 Irr.
Very Disliked Full details ->
2-Oleamido-1,3-Octadecanediol Skin Conditioning

We don't have a description for 2-Oleamido-1,3-Octadecanediol.

Unknown Full details ->
Propanediol Solvent

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

Hydroxyethoxyphenyl Butanone Preservative, Skin Conditioning
Preservative Icon
PreservativePreservative Icon

Hydroxyethoxyphenyl Butanone is a preservative.

Unknown Full details ->
Capryloyl Salicylic Acid Skin Conditioning

Capryloyl Salicylic Acid comes from salicylic acid, the famous acne-fighting BHA.

Citric Acid Buffering, Masking
AHA IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation IconMay worsen Rosacea Icon
AHAAHA Icon 4 Benefits 2 Concerns

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

Disliked Full details ->
Pentylene Glycol Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

Polysorbate 80 Emulsifying
0 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon
2 Concerns

Polysorbate 80 is a surfactant and emulsifier. It is used to keep ingredients together, and prevent oils and waters from separating.

0 Com. / 0 Irr.
Very Disliked Full details ->
Salicylic Acid Masking, Preservative, Skin Conditioning
BHA IconPreservative IconGood for Oily Skin IconGood for Minimizing Pores IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconCan worsen Dry Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon
BHABHA Icon PreservativePreservative Icon 5 Benefits 4 Concerns

Salicylic Acid (also known as beta hydroxy acid or BHA) is one of the most well-known ingredients for treating skin that struggles with blackheads and acne. It helps to exfoliate both the skin's surface and pores, and also acts as an anti-inflammatory agent.

Piroctone Olamine Preservative
Preservative Icon
PreservativePreservative Icon

Piroctone Olamine is a preservative.

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Emollient, Skin Conditioning, Skin Protecting
Very Disliked

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

Dimethicone has been found increase absorption in skin, boosting the benefits of other ingredients. While there is concern for the safety of dimethicone, the levels used in skincare are safe for use.

Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Smoothing
Loved

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide

Ingredient Ratings

Here's what our community thinks of the ingredients in these two products.

Regenerist Retinol 24 Night Facial Moisturizer
7
1
13
3
liked
mixed
disliked
not rated
Effaclar Duo+M
10
4
6
4
liked
mixed
disliked
not rated

When to use

143 Routines
3% use in am
97% use in pm
85% use every day
When to use See routines that use it ->
396 Routines
43% use in am
57% use in pm
87% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Olay Regenerist Retinol 24 Night Facial Moisturizer 24 ingredients

5.0 /5
from 1 rating
ShannonFernandes_161's avatar

ShannonFernandes_161

10 months ago · Combination Skin
Review

Has had the biggest impact in terms of clearning skin and overall skin health.

La Roche-Posay Effaclar Duo+M 24 ingredients

3.8 /5
from 6 ratings
Light (3) Great Value (2) Hydrating (2)
itspola's avatar

Pola 🐛

1 month ago · Oily Skin
Review

Doesn't do magic but definitely works well if you have some smaller pimples