MDacne Soothing Moisturizer Versus Clearstem Skincare Hydraglow Stem Cell Moisturizer
Updated on July 09, 2025
Overview
What they are
These products are both vegan, cruelty-free, and reef safe general moisturizers. They have a total of 9 ingredients in common
Cool Features
They both contain hyaluronic acid
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, common allergens, parabens, silicones or sulfates
What's Inside
They both contain fragrances
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
MDacne Soothing Moisturizer 21 ingredients
Clearstem Skincare Hydraglow Stem Cell Moisturizer 27 ingredients
What's inside
What's inside
At a glance
Click on any of the items below to learn more
MDacne Soothing Moisturizer 21 ingredients
Clearstem Skincare Hydraglow Stem Cell Moisturizer 27 ingredients
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningAloe Barbadensis Leaf Extract
Emollient
Glyceryl Stearate
Emollient
Stearic Acid
Cleansing
Cetyl Alcohol
Emollient
Glycerin
Humectant
Polysorbate 20
Emulsifying
Ascorbic Acid
Antioxidant
Camellia Sinensis Extract
Antioxidant
Cucumis Sativus Fruit Extract
Emollient
Punica Granatum Extract
AstringentGlycyrrhiza Glabra Root Extract
Bleaching
Butyrospermum Parkii Butter
Skin Conditioning
Theobroma Cacao Seed Butter
Emollient
Thioctic Acid
Antioxidant
Hyaluronic Acid
Humectant
Sodium Polyacrylate
Absorbent
Xanthan Gum
EmulsifyingPhenoxyethanol
Preservative
Ethylhexylglycerin
Skin ConditioningParfum
Masking
Water, Aloe Barbadensis Leaf Extract, Glyceryl Stearate, Stearic Acid, Cetyl Alcohol, Glycerin, Polysorbate 20, Ascorbic Acid, Camellia Sinensis Extract, Cucumis Sativus Fruit Extract, Punica Granatum Extract, Glycyrrhiza Glabra Root Extract, Butyrospermum Parkii Butter, Theobroma Cacao Seed Butter, Thioctic Acid, Hyaluronic Acid, Sodium Polyacrylate, Xanthan Gum, Phenoxyethanol, Ethylhexylglycerin, Parfum
Water
Skin ConditioningSqualane
Emollient
Propanediol
Solvent
Cannabis Sativa Seed Oil
Emollient
Punica Granatum Seed Oil
Emollient
Polyglyceryl-6 Distearate
Emulsifying
Glycerin
Humectant
Cetyl Alcohol
Emollient
Raphanus Sativus Seed Extract
Skin ConditioningBakuchiol
Antimicrobial
Aloe Barbadensis Leaf Extract
Emollient
Hyaluronic Acid
Humectant
Jojoba Esters
Emollient
Boswellia Carterii Oil
Masking
Camellia Sinensis Extract
Antioxidant
Sodium Cocoyl/Stearoyl (Alanine/Arginine/Asparagine/Aspartic Acid/Glutamic Acid/Glutamine/Glycine/Histidine/Isoleucine/Leucine/Lysine/Phenylalanine/Proline/Serine/Threonine/Tyrosine/Valine)
EmollientPhenylalanine
Masking
Argania Spinosa Sprout Cell Extract
Skin ConditioningCurcuma Longa Root Extract
Masking
Tanacetum Annuum Flower Oil
Masking
Lactobacillus Ferment
Skin ConditioningDiglucosyl Gallic Acid
Thioctic Acid
Antioxidant
Lactic Acid
Buffering
Xanthan Gum
EmulsifyingCaprylyl Glycol
Emollient
Ethylhexylglycerin
Skin ConditioningWater, Squalane, Propanediol, Cannabis Sativa Seed Oil, Punica Granatum Seed Oil, Polyglyceryl-6 Distearate, Glycerin, Cetyl Alcohol, Raphanus Sativus Seed Extract, Bakuchiol, Aloe Barbadensis Leaf Extract, Hyaluronic Acid, Jojoba Esters, Boswellia Carterii Oil, Camellia Sinensis Extract, Sodium Cocoyl/Stearoyl (Alanine/Arginine/Asparagine/Aspartic Acid/Glutamic Acid/Glutamine/Glycine/Histidine/Isoleucine/Leucine/Lysine/Phenylalanine/Proline/Serine/Threonine/Tyrosine/Valine), Phenylalanine, Argania Spinosa Sprout Cell Extract, Curcuma Longa Root Extract, Tanacetum Annuum Flower Oil, Lactobacillus Ferment, Diglucosyl Gallic Acid, Thioctic Acid, Lactic Acid, Xanthan Gum, Caprylyl Glycol, Ethylhexylglycerin
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Aloe Barbadensis Leaf Extract is an extract of the leaves of the aloe, Aloe barbadensis, Liliaceae.
Aloe is one of the most well-known natural soothing ingredients, and for good reason. It’s full of water and has a cooling, calming effect on the skin, especially when it’s sunburned, itchy, or irritated. Aloe also helps your skin stay hydrated and smooth by mimicking what healthy skin naturally produces. On top of that, it contains vitamins and nutrients that support skin recovery.Â
It doesn’t protect you from the sun, but it can help your skin bounce back after too much time in it.
Let’s get into the details:
Aloe contains antioxidant Vitamins A, C, and E, which help fight off free radicals (unstable molecules from things like pollution that can damage your skin).
It’s also rich in polysaccharides, which are natural sugars that help hydrate the skin by acting like the skin’s own moisturizing agents. These, along with other sugars like monosaccharides, help form a protective barrier that locks in moisture.
Aloe works as both a humectant and an emollient. That means it draws water into the skin (humectant) and helps trap it there (emollient), making it an effective natural moisturizer.
You’ll also find a mix of other skin-supporting ingredients in aloe, including folic acid, choline, calcium, amino acids, fatty acids, and even Vitamin B12.
Out of the 420+ species of aloe, Aloe barbadensis is the most widely used in skincare products thanks to its gentle yet effective properties.
There are over 420 species of aloe but Aloe Barbadensis is the most commonly used for topical products.
Learn more about Aloe Barbadensis Leaf ExtractCamellia Sinensis Extract is from the oil in tea plant leaves. The leaves give us various types of tea: green, black, oolong, and white.
Camellia Sinensis leaves have many benefits. It contains polyphenols, a strong antioxidant. Antioxidants help fight off free-radical molecules that damage skin cells. The antioxidants in green tea neutralize free-radicals from the sun. This gives the skin some extra UV protection, but should not replace sunscreen.
Many components of tea have anti-inflammatory and antimicrobial properties. Polyphenols and L-theanine help soothe the skin and reduce irritation. L-theanine is an amino acid that makes up most of the amino acids found in tea leaves. The caffeine in Camellia Sinensis Leaf Extract helps calm inflamed blood vessels.
Tea leaves also contain Vitamin Bs, linoleic acid, magnesium, calcium, iron, and zinc.
Research has shown both drinking Camellia Sinensis Leaf Tea and applying it to the skin can help boost skin elasticity and hydration. Studies also show using tea extract may reduce sebum, or oil, production.
Learn more about Camellia Sinensis ExtractCetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
Its main roles are:
Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.
The FDA allows products labeled "alcohol-free" to have fatty alcohols.
Learn more about Cetyl AlcoholEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinHyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.
This ingredient helps hydrate, soothe, and protect the skin.
What makes hyaluronic acid so hydrating? It has the capacity to bind or hold large amounts of water.
Fun fact: It is already naturally found in our bodies, such as the fluids of our eyes and our joints.
Studies find this ingredient to have anti-inflammatory and anti-microbial properties. This can help speed up wound-healing.
Hyaluronic acid can be irritating if the molecule has a low-molecular weight, or if the molecules are small.
One study found low-molecular weight hyaluronic acid to be pro-inflammatory, meaning some people may experience irritation. This is because our bodies use hyaluronic acid in the wound-healing process to signal to our bodies, via irritation, that something needs healing.
The same study found high-molecular weight hyaluronic acid to be anti-inflammatory.
These are some other common types of Hyaluronic Acid:
Learn more about Hyaluronic AcidThioctic Acid is an enzyme and antioxidant. A more common name for this is Alpha Lipoic Acid.
Alpha Lipoic Acid can be naturally found in the mitochondria of every cell.
Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells. The antioxidants in Alpha Lipoic Acid have been shown to fight damage from cigarette smoke.
Studies also show Alpha Lipoic Acid plays a role in wound healing.
Thioctic Acid will break down when exposed to sunlight.
Many foods contain thioctic acid, including tomato, brussel sprouts, spinach, and broccoli.
Learn more about Thioctic AcidWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
MDacne Soothing Moisturizer 21 ingredients
Clearstem Skincare Hydraglow Stem Cell Moisturizer 27 ingredients
Reviews
Here's what our community thinks
