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Updated on August 16, 2023

Overview

What they are

These products are both vegan, cruelty-free, and reef safe ampoules. They have a total of 6 ingredients in common

Cool Features

They both contain hyaluronic acid

Suited For

They're both likely to be good for dry skin, brightening skin and sensitive skin

Free From

They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Isntree Onion Newpair B5 Ampoule
Isntree Onion Newpair B5 Ampoule
Ampoule
South Korean Brand South Korea
Anua Heartleaf 80% Soothing Ampoule
Anua Heartleaf 80% Soothing Ampoule
Ampoule
South Korean Brand South Korea

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Benefits

Ingredients Side-by-side

found in both products
Onion Newpair B5 Ampoule
Allium Cepa Bulb Extract Skin Conditioning

Red onion extract? This ingredient not only benefits our diet but also offers numerous benefits for the skin.

Panthenol Skin Conditioning
0 / 0 Helps reduce irritation Icon
Helps reduce irritationHelps reduce irritation Icon

Panthenol (also referred to as pro-vitamin B5) is a common ingredient that helps hydrate and soothe the skin.

0 Com. / 0 Irr.
1,2-Hexanediol Skin Conditioning, Solvent

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Trehalose Humectant, Moisturising

Trehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.

Betaine Humectant, Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon
3 Benefits

Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.

Acrylates Copolymer

Acrylates Copolymer is used as a film-forming agent and texture enhancer.

Disliked Full details ->
Arginine Masking, Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Allantoin Skin Conditioning, Skin Protecting, Soothing
0 / 0 Helps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon
3 Benefits

Allantoin plays a role in soothing and moisturizing the skin. Because of this, it is often added to products with strong active ingredients.

0 Com. / 0 Irr.
Pentylene Glycol Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

Hydroxyacetophenone Antioxidant
Antioxidant Icon
AntioxidantAntioxidant Icon

Hydroxyacetophenone is antioxidant and helps with skin conditioning.

Caffeine Skin Conditioning

Caffeine is most associated with coffee, tea, and cacao. In skincare, it helps with calming inflammation and anti-aging.

Acetyl Glucosamine Skin Conditioning

Acetyl Glucosamine is an antioxidant and humectant. It is a form of Vitamin C.

Melia Azadirachta Flower Extract Skin Conditioning

Melia Azadirachta Flower Extract is from the Neem tree. Neem trees originate from India.

Adenosine Skin Conditioning
Helps with Anti-Aging IconGood for Scar Healing Icon
2 Benefits

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Ammonium Acryloyldimethyltaurate/Vp Copolymer (let's call it AAVC for short) is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.

Disliked Full details ->
Coccinia Indica Fruit Extract Skin Conditioning

We don't have a description for Coccinia Indica Fruit Extract.

Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Tranexamic Acid Astringent, Skin Conditioning
Good for Dark Spots Icon
Good for Dark SpotsGood for Dark Spots Icon

Tranexamic Acid is best used for treating hyperpigmentation, discoloration, and melasma. It can also help build a stronger skin barrier.

Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Hydrolyzed Hyaluronic Acid Humectant, Skin Conditioning
Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Hydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.

Sodium Acetylated Hyaluronate Humectant
Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Acetylated Hyaluronate is a type of Hyaluronic Acid.

Ferulic Acid Antimicrobial, Antioxidant
Antioxidant IconHelps with Anti-Aging Icon
AntioxidantAntioxidant Icon Helps with Anti-AgingHelps with Anti-Aging Icon

Ferulic Acid is a plant based antioxidant. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells. Ferulic Acid can help reduce the formation of fine lines and hyperpigmentation.

Heartleaf 80% Soothing Ampoule
Houttuynia Cordata Extract Skin Conditioning
Helps reduce Skin Redness Icon
Helps reduce Skin RednessHelps reduce Skin Redness Icon

Houttuynia Cordata Extract is more commonly known as Heart Leaf, Fish Mint, or Chameleon plant.

Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
1,2-Hexanediol Skin Conditioning, Solvent

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

Betaine Humectant, Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon
3 Benefits

Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.

Cassia Obtusifolia Seed Extract Skin Conditioning

We don't have a description for Cassia Obtusifolia Seed Extract.

Unknown Full details ->
Panthenol Skin Conditioning
0 / 0 Helps reduce irritation Icon
Helps reduce irritationHelps reduce irritation Icon

Panthenol (also referred to as pro-vitamin B5) is a common ingredient that helps hydrate and soothe the skin.

0 Com. / 0 Irr.
Hydroxyethylcellulose Emulsion Stabilising, Stabilising

Hydroxyethylcellulose is used to improve the texture of products. It is created from a chemical reaction involving ethylene oxide and alkali-cellulose. Cellulose is a sugar found in plant cell walls and help give plants structure.

Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Arginine Masking, Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning
Loved

Panthenol (also referred to as pro-vitamin B5) is a common ingredient that helps hydrate and soothe the skin.

lt is a humectant, meaning that it helps the skin attract and retain moisture.

Another benefit is the anti-inflammatory abilities. This means that it's great for sensitive, irritation-prone skin.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

Learn more about Panthenol
Skin Conditioning, Solvent
Mixed

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

In products that are water-based, this ingredient can help stabilize perfumes and fragrances. It can also help make the texture of products softer and more smooth.

Humectant, Skin Conditioning
Loved

Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.

Betaine is best for improving hydration and soothing irritated skin. Studies show betaine may help with uneven skin tones.

Betaine is naturally created in the skin and body. The form found within cosmetic products can be either plant-dervied or synthetic.

Learn more about Betaine
Masking, Skin Conditioning
Mixed

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

As a cosmetic ingredient, Arginine has antioxidant properties and can also help repair damaged skin. This ingredient is derived either synthetically or from animals.

Arginine isn't fungal acne safe when used in the presence of other lipids (fats, fatty acids, oils, esters, etc). Oils and fats occur naturally within the skin, so take caution when using Arginine if you're prone to fungal acne.

Learn more about Arginine
Humectant, Masking, Skin Conditioning
Mixed

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.

Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.

Humectant, Skin Conditioning
Loved

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate

Ingredient Ratings

Here's what our community thinks of the ingredients in these two products.

Onion Newpair B5 Ampoule
19
4
3
liked
mixed
disliked
not rated
Heartleaf 80% Soothing Ampoule
5
5
1
1
liked
mixed
disliked
not rated

When to use

42 Routines
60% use in am
40% use in pm
86% use every day
When to use See routines that use it ->
138 Routines
41% use in am
59% use in pm
95% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Isntree Onion Newpair B5 Ampoule 26 ingredients

5.0 /5
from 2 ratings

Anua Heartleaf 80% Soothing Ampoule 12 ingredients

2.0 /5
from 1 rating
Doesn't Work (1) Great Value (1) Hydrating (1) Light (1) No Scent (1)
applepiewithwhipcream's avatar

applepiewithwhipcream

11 days ago · Combination Skin
Review

did nothing??? i mean it’s a little hydrating but didn’t soothe my skin in any way 😭
i guess it just wasn’t as effective for my skin 😓

update:...

did nothing??? i mean it’s a little hydrating but didn’t soothe my skin in any way 😭
i guess it just wasn’t as effective for my skin 😓

update: so i used it for the last time and i had some sort of reaction??? like i got a bump but idk if it was acne or not (wasn’t cystic acne i think) it wasn’t red but it calmed down after not using it 😞