IPSA Me Ultimate Lotion Formula 1

IPSA Me Ultimate Lotion

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Overview

What it is

Emulsion with 38 ingredients that contains retinoid and Vitamin E

Cool Features

It is reef safe

Suited For

It has ingredients that are good for anti aging, dry skin, brightening skin, scar healing and dark spots

Free From

It doesn't contain any common allergens, fragrances, parabens or sulfates

Fun facts

IPSA is from Japan.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

What's inside

Ingredients List

Key Ingredients

Benefits

Concerns

Ingredients Explained

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Learn more about Water
Antimicrobial, Astringent, Masking

This ingredient is also called ethanol or ethyl alcohol. It is denatured, meaning made undrinkable for cosmetic use.

In formulas, it:

Is it bad for your skin?

The answer comes down to concentration. Patch and wash studies have found highly concentrated alcohol-based hand rubs (60-100%) cause less barrier disruption than washing with a basic detergent like SLS. The only measurable effect in these studies was a temporary dip in skin hydration.

Concentrations below 12-15% in leave-on cosmetics is generally well-tolerated. Concentrations above start to see increased transepidermal water loss (TEWL) and reduced hydration.

In concentrations about 58%, it creates temporary channels in your skin's lipid layers to become more permeable and allow other ingredients to slip through easily.

This ingredient can be up to 80% of the formula in alcohol-based perfumes.

Overall, this ingredient is probably harmless if found lower down an ingredients list but worth side-eyeing if it's high up (especially if your barrier is already struggling).

Alcohol can worsen dry skin, eczema, and oily skin, especially at higher concentrations. This is because it can increase transepidermal water loss and decrease hydration to disrupt the skin barrier.

According to the National Rosacea Society based in the US, you should be mindful of products with these alcohols in the top half of ingredients.

True allergic contact dermatitis to ethanol is uncommon, but be sure to patch test if you have dry or sensitive skin.

Learn more about Alcohol
Humectant, Masking, Solvent

Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.

This ingredient helps:

Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the โ€˜goodโ€™ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Learn more about Dipropylene Glycol
Humectant, Skin Conditioning, Skin Protecting

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emollient, Masking, Skin Conditioning

Hydrogenated Polydecene is a synthetic emollient. It forms a non-occlusive film on the skin's surface to provide a silky feel without being greasy.

In vivo studies in volunteers with atopic and dry skin showed no irritation or intolerance. The volunteers also saw a positive effect in dryness, scaling, and roughness after 28 days of use.

Concentrations up to 100% in guinea pig tests found it to be non-sensitizing and completely safe for use in cosmetics.

Learn more about Hydrogenated Polydecene
Emollient, Skin Conditioning, Skin Protecting

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Learn more about Dimethicone
Emulsion Stabilising, Solvent

Peg-400 is an emulsion stabilizer and prevents ingredients from separating. It is a form of polyethylene glycol.

The 400 stands for the molecular weight of this compound.

Skin Conditioning

We don't have a description for PEG/PPG-14/7 Dimethyl Ether yet.

We don't have a description for Potassium Methoxysalicylate yet.

Masking, Skin Conditioning

Triethylhexanoin is created from glycerin and 2-ethylhexanoic acid. It is a solvent and emollient.

As a solvent, Triethylhexanoin helps dissolve ingredients to stable bases or help evenly distribute ingredients throughout the product.

It is also an emollient and helps condition the skin.

Learn more about Triethylhexanoin

We don't have a description for Phytosteryl/Octyldodecyl Lauroyl Glutamate yet.

Skin Conditioning

PEG-12 Dimethicone is a type of water-soluble silicone. It has skin conditioning and hydrating properties.

According to a manufacturer, this ingredient's stability is decreased by strong acid or alkali.

Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Emulsion Stabilising, Gel Forming

Carbomer is a high-molecular weight polymer of acrylic acid. It is used to form gels and thicken formulas.

Due to its large molecular size, carbomer has minimal skin penetration and is considered an inert ingredient.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Learn more about Carbomer
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum

Potassium hydroxide is commonly known as caustic potash. It is used to fix the pH of a product or as a cleaning agent in soap. In cleansers, it is used for the saponification of oils.

Sapnification is the process of creating fatty acid metal salts from triglycerides and a strong base. During this process, Potassium Hydroxide is used up and is not present in the final product.

Using high concentrations of Potassium Hydroxide have shown to irritate the skin.

Learn more about Potassium Hydroxide
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Learn more about Disodium EDTA
Antioxidant, Skin Conditioning

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
Skin Conditioning, Surfactant

We don't have a description for Hydroxyproline yet.

Skin Conditioning

We don't have a description for Arginine Hcl yet.

Masking, Skin Conditioning

Serine is a non-essential amino acid (your body makes it on its own!). It is a major player in your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

Serine is one of your NMF's most abundant components that works as a skin-identical humectant. Its hydroxyl group grabs onto water molecules to boost hydration without any heaviness or occlusion.

Research on a hydrogel with serine confirmed this serine got delivered to your stratum corneum and demonstrated enhanced skin moisturization.

Interestingly serine also helps your skin produce filaggrin, a protein that keeps your skin barrier strong and used to create collagen.

Learn more about Serine
Cleansing, Foaming, Surfactant

This ingredient is a sulfate-free surfactant. It is made by combining a fatty acid with taurine.

According to a manufacturer, the taurine component of this ingredient makes it suitable for sensitive skin. As a surfactant, it helps cleanse without stripping and helps produce a creamy foam.

Cleansing, Emulsifying, Surfactant

Isostearic Acid is a fatty acid and a structural cousin of stearic acid. It is an emulsifier.

The branched structure of this ingredient enhances fluidity and gives it a lighter, less greasy feel compared to other fatty acids. It helps improve texture and consistency because it prevents oil and water phases from separating.

This ingredient is sourced from plant-based oils like soybean or rapeseed.

Clinical studies found no signs of irritation from this ingredient.

Since Isostearic Acid is an 18-carbon fatty acid, it is in the range that Malassezia can feed on. This ingredient may not be fungal acne safe.

You might have seen sources that this ingredient is comedogenic. This is because the original comedogenic tests (on rabbit ears, which are more sensitive than human skin) tested

The Kligman/Fulton rabbit ear papers actually tested the ester, Isopropyl Isostearate and not Isostearic acid itself. There has been no comedogenic testing done on this ingredient, but it may be worth patch testing if you have acne-prone skin.

Learn more about Isostearic Acid

Natto Gum is created by fermenting a soy protein using Bacillus natto (a bacteria). It is used as a texture enhancer.

Natto gum contains nattokinase, an enzyme. It is currently being studied for its ability to improve blood circulation.

Studies also show fermented soy-based ingredients help boost antioxidant activity.

Learn more about Natto Gum
Cleansing, Skin Conditioning, Surfactant

Lauryl Betaine is a cleansing ingredient. You'll most likely see it in face washes, body washes, and shampoos. It's a type of surfactant that helps water mix with oil so dirt, sweat, and sunscreen can rinse off easily.

Chemically, lauryl betaine is an amphoteric surfactant so it carries both a positive and negative charge. This helps it create a creamy foam while being less harsh than stronger detergent-type cleansers.

According to CIR, this ingredient is generally considered safe when used in cosmetics. However, like all surfactants, it can be irritating when used in high amounts of in formulas that aren't well balanced.

Learn more about Lauryl Betaine

We don't have a description for Belamcanda Chinensis Root Extract yet.

Buffering, Skin Conditioning

Glycine is the smallest amino acid and a key building block of collagen. It's part if your skin's Natural Moisturizing Factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

A study from 2022 found that an amino acid complex featuring taurine, arginine, and glycine significantly reduced skin irritation, improved redness, and accelerated the skin repair process.

Astringent, Humectant, Soothing

Scutellaria Baicalensis Root Extract comes from the Baikal skullcap or Chinese skullcap plant. This plant is native to Northeast Asia and can be found in China, Mongolia, Korea, and Siberia.

In cosmetics, Scutellaria Baicalensis Root Extract provides antioxidant and anti-inflammatory benefits. This is due to the flavonoid composition of Scutellaria Baicalensis Root Extract.

In Chinese traditional folk medicine, Scutellaria Baicalensis Root Extract is used to help treat lung issues and hypertension.

Learn more about Scutellaria Baicalensis Root Extract

We don't have a description for Bupleurum Falcatum Root Extract yet.

Antioxidant, Masking, Skin Conditioning

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Learn more about Tocopherol
Skin Conditioning

Retinyl Acetate is part of the retinoid family. It is made from retinol and acetic acid.

Though retinyl acetate is more stable than retinol, it is also less effective and less irritating. This is due to the conversion line all retinoids have to go through.

All retinoids must be converted to retinoic acid. The further away from this end result, the less effective the ingredient is.

Fun fact: Retinyl acetate is commonly used as a Vitamin C additive for foods.

Learn more about Retinyl Acetate
Skin Conditioning

We don't have a description for Pyrola Incarnata Extract yet.

Emollient, Masking, Skin Conditioning

Helianthus Annuus Seed Oil is a plant oil derived from the seeds of a sunflower.

It is rich in fatty acids, primarily linoleic acid and oleic acid. This gives it emollient and skin conditioning properties.

The reason this ingredient is so effective is because it forms a thin film on the skin that reduces transepidermal water loss (TEWL) while supplying linoleic acid to the stratum corneum to improve barrier strength.

The high linoleic acid content is particularly noteworthy for acne-prone skin.

Research suggests that acne-prone skin tends to be deficient in linoleic acid in sebum. Topical application may help replenish this to support a healthier follicular environment and less comedone-promoting sebum.

One randomized study found sunflower seed oil preserved skin barrier integrity in adult volunteers with and without atopic dermatitis (outperforming olive oil).

This ingredient is well-studied, gentle, and an effective emollient suitable for most skin types.

On fungal acne: This ingredient may not be Fungal acne (Malassezia folliculitis) safe. This is because it contains fatty acids with carbon chain lengths in the C11-C24 range.

Learn more about Helianthus Annuus Seed Oil
Skin Conditioning

We don't have a description for Zingiber Aromaticus Extract yet.

Skin Conditioning

We don't have a description for Thymus Serpyllum Extract yet.

BHT
Antioxidant, Masking

BHT is a synthetic antioxidant and preservative.

As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.

As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.

The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.

However, it was recently restricted for use in the UK as of April 2024.

Learn more about BHT
Masking, Preservative

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Learn more about Sodium Benzoate

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Where it's from

IPSA is a Japanese brand

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ยท Updated October 19, 2025 Added by mscarletinthelibrary