The Agency Dark Spot FormulaRX Versus Curology Custom Formula Tretinoin 0.018%, Clindamycin 1%, Azelaic Acid 8%
Updated on May 31, 2025
Overview
What they are
These products are both cruelty-free and reef safe prescription. They have a total of 3 ingredients in common
Cool Features
They both contain Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
The Agency Dark Spot FormulaRX 25 ingredients
Curology Custom Formula Tretinoin 0.018%, Clindamycin 1%, Azelaic Acid 8% 12 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
The Agency Dark Spot FormulaRX 25 ingredients
Curology Custom Formula Tretinoin 0.018%, Clindamycin 1%, Azelaic Acid 8% 12 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Hydroquinone 4%
Stabilising
Kojic Acid 4%
Antioxidant
Azelaic Acid 3%
Buffering
Resveratrol
Antioxidant
Water
Skin ConditioningCetearyl Alcohol
Emollient
Polysorbate 60
Emulsifying
Isohexadecane
EmollientIsododecane
EmollientC13-15 Alkane
SolventGlyceryl Stearate
Emollient
PEG-75 Stearate
Polyacrylate-13
Polyisobutene
Polysorbate 20
Emulsifying
Polyurethane-39
Stearyl Behenate
Emollient
Cetyl Alcohol
Emollient
Tocopheryl Acetate
Antioxidant
Ascorbic Acid
Antioxidant
Sodium Bisulfite
Antioxidant
Benzoic Acid 0.09%
Masking
Sorbic Acid 0.09%
Preservative
BHT
Antioxidant
Propanediol
Solvent
Hydroquinone 4%, Kojic Acid 4%, Azelaic Acid 3%, Resveratrol, Water, Cetearyl Alcohol, Polysorbate 60, Isohexadecane, Isododecane, C13-15 Alkane, Glyceryl Stearate, PEG-75 Stearate, Polyacrylate-13, Polyisobutene, Polysorbate 20, Polyurethane-39, Stearyl Behenate, Cetyl Alcohol, Tocopheryl Acetate, Ascorbic Acid, Sodium Bisulfite, Benzoic Acid 0.09%, Sorbic Acid 0.09%, BHT, Propanediol
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Azelaic acid is a naturally occurring acid derived from grains. This ingredient is effective in treating acne, rosacea, and other skin conditions.
It has been shown to reduce the growth of acne-causing bacteria and helps reduce inflammation. On top of that, it helps reduce the production of sebum and unclog pores.
Azelaic Acid also has antioxidant properties. Antioxidants protect our skin cells from free-radical damage.
One of the main benefits of azelaic acid is that it is gentle and well-tolerated by most people.
Fun fact: The lab-created form of azelaic acid is typically used within cosmetic products for its shelf-stability.
Learn more about Azelaic AcidTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterIngredient Ratings
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When to use
The Agency Dark Spot FormulaRX 25 ingredients
Curology Custom Formula Tretinoin 0.018%, Clindamycin 1%, Azelaic Acid 8% 12 ingredients
Reviews
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