What's inside
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Skin ConditioningButylene Glycol
Humectant
Glycerin
Humectant
Diethoxyethyl Succinate
SolventRetinol
Skin Conditioning
Retinal
Skin Conditioning
Dimethicone/Vinyl Dimethicone Crosspolymer
Skin Conditioning
1,2-Hexanediol
Skin Conditioning
Hydroxypinacolone Retinoate
Skin Conditioning
Niacinamide
Smoothing
Propanediol
Solvent
Carbomer
Emulsion StabilisingAmmonium Acryloyldimethyltaurate/Vp Copolymer
Calcium Alginate
MaskingAgar
MaskingPalmitoyl Pentapeptide-4
Skin Conditioning
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Skin Conditioning
Acetyl Tetrapeptide-5
Humectant
Sodium Hyaluronate
Humectant
Disodium EDTA
Ceramide As
Skin Conditioning
Centella Asiatica Extract
Cleansing
Dipotassium Glycyrrhizate
Humectant
Ceramide Ns
Skin Conditioning
Ceramide Ng
Skin Conditioning
Tocopherol
Antioxidant
Ceramide NP
Skin Conditioning
Ceramide AP
Skin Conditioning
Ceramide EOP
Skin Conditioning
O-Cymen-5-Ol
Antimicrobial
Pentylene Glycol
Skin Conditioning
Caprylhydroxamic Acid
Gentiana Scabra Root Extract
Skin ConditioningPiper Methysticum Leaf/Root/Stem Extract
Skin ConditioningCarnosine
Skin Conditioning
Polygonum Bistorta Root Extract
Skin ConditioningHexylene Glycol
EmulsifyingPalmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Water, Butylene Glycol, Glycerin, Diethoxyethyl Succinate, Retinol, Retinal, Dimethicone/Vinyl Dimethicone Crosspolymer, 1,2-Hexanediol, Hydroxypinacolone Retinoate, Niacinamide, Propanediol, Carbomer, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Calcium Alginate, Agar, Palmitoyl Pentapeptide-4, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetyl Tetrapeptide-5, Sodium Hyaluronate, Disodium EDTA, Ceramide As, Centella Asiatica Extract, Dipotassium Glycyrrhizate, Ceramide Ns, Ceramide Ng, Tocopherol, Ceramide NP, Ceramide AP, Ceramide EOP, O-Cymen-5-Ol, Pentylene Glycol, Caprylhydroxamic Acid, Gentiana Scabra Root Extract, Piper Methysticum Leaf/Root/Stem Extract, Carnosine, Polygonum Bistorta Root Extract, Hexylene Glycol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Hydroxypinacolone Retinoate (aka Granactive Retinoid or HPR) is a retinoid that is part of the same vitamin A family as retinol.
It is an ester of retinoic acid that binds directly to your skin's retinoic acid receptors so it doesn't need your skin to convert it through several steps before it can do anything.
In practice, this means it does the classic retinoid jobs in a formula:
The best part is that it can do all this with noticeably less redness, flaking, and stinging than traditional retinoids.
That gentle reputation is backed by lab work as well; a 2018 study on skin models found that HPR triggered higher retinoid-gene activity than retinol, retinal, or retinyl propionate at the same concentrations while being less irritating to cells.
It also boosted procollagen production to levels similar to retinoic acid itself.
A 2023 study showed HPR works synergistically with retinyl propionate to switch on collagen-building pathways and a 2025 clinical serum study in women with mild photoaging saw improvements in wrinkles and elasticity (though that formula also contained retinol, peptides, and Silybin).
One naming quirk worth mentioning:
You'll likely see this ingredient sold under the trade name "Granactive Retinoid", which is actually only 10% HPR blended with 90% Dimethyl Isosorbide solvent. This means a 5% Granactive Retinoid really only means about 0.5% HPR.
Finished products typically land somewhere between 0.05-1% and it's happiest formulated at a mildly acidic to neutral pH (~5.5-6.5).
Another perk is that this is one of the more light- and temperature-stable retinoids which is a nice bonus for shelf life.
Learn more about Hydroxypinacolone Retinoate
