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Updated on July 18, 2023

Overview

What they are

These products are both reef safe serums. They have a total of 4 ingredients in common

Cool Features

They both contain hyaluronic acid

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, scar healing, dark spots and better texture

Free From

They both do not contain any common allergens or parabens

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Is Clinical Super Serum Advance+
La Roche-Posay Retinol B3 Serum

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Super Serum Advance+
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Ascorbic Acid Antioxidant, Buffering, Masking
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon
Vitamin CVitamin C Icon AntioxidantAntioxidant Icon 6 Benefits

Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.

Hyaluronic Acid Humectant, Moisturising, Skin Conditioning
Hyaluronic Acid IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation Icon
Hyaluronic AcidHyaluronic Acid Icon 4 Benefits May cause irritationMay cause irritation Icon

Hyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.

Pentylene Glycol Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

Urea Buffering, Humectant, Skin Conditioning
Helps hydrate Dry Skin IconGood for Skin Texture IconMay worsen Eczema IconMay worsen Rosacea Icon
2 Benefits 2 Concerns

Urea is also called carbamide and is the diamide of carbonic acid. In cosmetics, urea is used to hydrate the skin. It also provides exfoliation in higher concentrations.

Glucose Humectant

Glucose is a simple sugar and is the most important source of energy in all organisms.

Guanidine Hcl Buffering

We don't have a description for Guanidine Hcl.

Unknown Full details ->
Tripeptide-1 Skin Conditioning, Skin Protecting
Peptide Icon
PeptidePeptide Icon

Tripeptide-1 is a peptide.

Arbutin Antioxidant, Bleaching, Skin Conditioning
Antioxidant IconGood for Dark Spots IconGood for Scar Healing Icon
AntioxidantAntioxidant Icon 2 Benefits

Arbutin is derived from the bearberry plant. It helps even out skin tone and reduce hyperpigmentation.

Polyporus Umbellatus Extract Skin Protecting

We don't have a description for Polyporus Umbellatus Extract.

Unknown Full details ->
Calcium Pantothenate

Calcium Pantothenate is calcium salt from Vitamin B5. It can be naturally found in plants and animals.

Asiaticoside Antioxidant, Skin Conditioning
Antioxidant Icon
AntioxidantAntioxidant Icon

Asiaticoside comes from the super popular skin-soothing ingredient, Centella asiatica. It is one of four active compounds found in the extract of Centella Asiatica.

Asiatic Acid Skin Conditioning, Stabilising

Asiatic Acid is a major component of Centella Asiatica Extract. It has wound-healing, anti-inflammatory, and antioxidant properties.

Zinc Sulfate Antimicrobial, Astringent
Sulfate Icon
SulfateSulfate Icon

Zinc Sulfate is a type of sulfate.

Disliked Full details ->
Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Retinol B3 Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Cyclohexasiloxane Emollient, Skin Conditioning, Solvent
Silicon Icon
SiliconSilicon Icon

Cyclohexasiloxane is a type of silicone more commonly known as D6. It is an emollient and solvent.

Disliked Full details ->
Alcohol Denat. Antimicrobial, Astringent, Masking
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon
AlcoholAlcohol Icon 5 Concerns

Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.

Very Disliked Full details ->
Pentylene Glycol Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0 Silicon Icon
SiliconSilicon Icon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

1 Com. / 0 Irr.
Very Disliked Full details ->
Glycine Soja Oil Emollient, Skin Conditioning
3 / 0 Oil IconNot safe for Fungal Acne Icon
OilOil Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Glycine Soja Oil comes from the soybean. Glycine Soja is native to eastern Asia.

3 Com. / 0 Irr.
Very Disliked Full details ->
Ppg-6-Decyltetradeceth-30 Emulsifying

We don't have a description for Ppg-6-Decyltetradeceth-30.

Unknown Full details ->
Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Retinol Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconCan worsen Dry Skin IconMay cause irritation IconMay worsen Eczema Icon
RetinoidRetinoid Icon 8 Benefits 3 Concerns

Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.

Adenosine Skin Conditioning
Helps with Anti-Aging IconGood for Scar Healing Icon
2 Benefits

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Ammonium Polyacryloyldimethyl Taurate Emulsion Stabilising

Ammonium Polyacryloyldimethyl Taurate is a polymer made from ammonium salts. It helps add stability and texture to a product.

Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Citric Acid Buffering, Masking
AHA IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation IconMay worsen Rosacea Icon
AHAAHA Icon 4 Benefits 2 Concerns

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

Disliked Full details ->
Trisodium Ethylenediamine Disuccinate

Trisodium Ethylenediamine Disuccinate is used to help stabilize a product.

Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Polysilicone-11

We don't have a description for Polysilicone-11.

Disliked Full details ->
Retinyl Palmitate Skin Conditioning
1-3 / 1-3 Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconCan worsen Dry Skin IconMay cause irritation IconNot safe for Fungal Acne Icon
RetinoidRetinoid Icon 7 Benefits 3 Concerns

Retinyl palmitate is a form of retinoid. Retinoids are the superstar class of anti-aging ingredients that include tretinoin and retinol.

1-3 Com. / 1-3 Irr.
Tocopherol Antioxidant, Masking, Skin Conditioning
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon 4 Benefits May cause irritationMay cause irritation Icon

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

0-3 Com. / 0-3 Irr.
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Parfum Masking, Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon
FragranceFragrance Icon 2 Concerns

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Very Disliked Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Skin Conditioning, Solvent
Mixed

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.

This property also makes Pentylene Glycol a great texture enhancer. It can help thicken or emulsify a product. Emulsifiers help stabilize a product. It does this by preventing certain ingredients from separating.

Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.

Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.

Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.

Learn more about Pentylene Glycol
Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Preservative
Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Ingredient Ratings

Here's what our community thinks of the ingredients in these two products.

Super Serum Advance+
11
1
2
2
liked
mixed
disliked
not rated
Retinol B3 Serum
10
2
9
1
liked
mixed
disliked
not rated

When to use

10 Routines
100% use in am
0% use in pm
90% use every day
223 Routines
7% use in am
93% use in pm
67% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Is Clinical Super Serum Advance+ 16 ingredients

5.0 /5
from 1 rating
Steffie90's avatar

Steffie90

9 months ago · Combination Skin
Review

Helps so much with texture and fine lines

La Roche-Posay Retinol B3 Serum 22 ingredients

2.5 /5
from 2 ratings
carolperroud's avatar

carolperroud

1 year ago · Oily Skin
Review

Breakout
I woke up with oily skin and bumps after using this product

Lapaki's avatar

Lapaki

1 year ago · Dry Skin
Review

Very good and gentle retinol serum
My retinol journey began with this gentle serum with a concentration of 0.3% retinol: 0.1% pure retinol combined...

Very good and gentle retinol serum
My retinol journey began with this gentle serum with a concentration of 0.3% retinol: 0.1% pure retinol combined with 0.2% retinol palmitate that ensures gradual release of the active ingredients. It din't irritate my skin or cause any major break-outs, just some slight purging in the beginning, but that is concidered a normal reaktion that fades as soon as the skin gets used to it. I recommend it for retinol beginners and people with sensitive skin. [Edited]