ZO Skin Health Growth Factor Serum Versus Hydropeptide Clear Rescue Skin Refining Serum
Updated on April 09, 2025
Overview
What they are
These products are both reef safe serums. They have a total of 4 ingredients in common
Cool Features
They both contain peptides and Vitamin E
Suited For
They're both likely to be good for dry skin, brightening skin and sensitive skin
Free From
They both do not contain any harsh alcohols, common allergens or parabens
What's Inside
They both contain fragrances and silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
ZO Skin Health Growth Factor Serum 34 ingredients
Hydropeptide Clear Rescue Skin Refining Serum 32 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
ZO Skin Health Growth Factor Serum 34 ingredients
Hydropeptide Clear Rescue Skin Refining Serum 32 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningCyclopentasiloxane
Emollient
Dipropylene Glycol
MaskingPropylene Glycol
Humectant
Dimethicone
Emollient
Glycerin
Humectant
Dimethicone Crosspolymer
Emulsion StabilisingDimethicone/PEG-10/15 Crosspolymer
PEG-12 Dimethicone Crosspolymer
EmulsifyingButylene Glycol
Humectant
Dimethicone/Vinyl Dimethicone Crosspolymer
Skin ConditioningSodium Phosphate
BufferingPanthenyl Triacetate
Phospholipids
Skin ConditioningMagnesium Sulfate
Hydrolyzed Sericin
Skin ConditioningEthyl Linoleate
Emollient
Buddleja Davidii Meristem Cell Culture
Skin ConditioningAngelica Polymorpha Sinensis Root Extract
Skin ConditioningDipeptide Diaminobutyroyl Benzylamide Diacetate
Skin Conditioning
Lactobacillus/Panax Ginseng Root Extract Ferment Filtrate
Skin ConditioningDisodium Acetyl Glucosamine Phosphate
Skin ConditioningAcetyl Tyrosine
Skin ConditioningDimethiconol
Emollient
Oleyl Alcohol
Emollient
Proline
Skin ConditioningParfum
Masking
Tocopherol
Antioxidant
Beta-Glucan
Skin Conditioning
Adenosine Triphosphate
Skin ConditioningHydrolyzed Vegetable Protein
Skin ConditioningSodium Chloride
Masking
Xanthan Gum
EmulsifyingPhenoxyethanol
Preservative
Water, Cyclopentasiloxane, Dipropylene Glycol, Propylene Glycol, Dimethicone, Glycerin, Dimethicone Crosspolymer, Dimethicone/PEG-10/15 Crosspolymer, PEG-12 Dimethicone Crosspolymer, Butylene Glycol, Dimethicone/Vinyl Dimethicone Crosspolymer, Sodium Phosphate, Panthenyl Triacetate, Phospholipids, Magnesium Sulfate, Hydrolyzed Sericin, Ethyl Linoleate, Buddleja Davidii Meristem Cell Culture, Angelica Polymorpha Sinensis Root Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Lactobacillus/Panax Ginseng Root Extract Ferment Filtrate, Disodium Acetyl Glucosamine Phosphate, Acetyl Tyrosine, Dimethiconol, Oleyl Alcohol, Proline, Parfum, Tocopherol, Beta-Glucan, Adenosine Triphosphate, Hydrolyzed Vegetable Protein, Sodium Chloride, Xanthan Gum, Phenoxyethanol
Water
Skin ConditioningEthyl Macadamiate
Skin Conditioning
Dimethicone
Emollient
Behenoxy Dimethicone
Emollient
Glyceryl Stearate Se
Emulsifying
Lysozyme
Skin ConditioningCocoyl Argininamide
Skin ConditioningSalicylic Acid
Masking
Sodium Hyaluronate
Humectant
Glyceryl Stearate
Emollient
Juniperus Communis Wood Oil
Perfuming
Tocopheryl Acetate
Antioxidant
Lactobacillus Ferment Lysate
Skin Conditioning
Decylene Glycol
Skin ConditioningButylene Glycol
Humectant
Propanediol
SolventMirabilis Jalapa Extract
Skin ConditioningSodium Carboxymethyl Betaglucan
Aloe Barbadensis Leaf Juice
Skin Conditioning
Polyglyceryl-10 Laurate
Skin Conditioning
Capryloyl Glycine
CleansingCocoglycerides
Emollient
Maltodextrin
AbsorbentSyringa Vulgaris Extract
Skin ConditioningBeta-Glucan
Skin Conditioning
Hydroxyethylcellulose
Emulsion StabilisingMyristoyl Tetrapeptide-13
Skin Conditioning
Myristoyl Pentapeptide-16
Skin Conditioning
Caprylyl Glycol
Emollient1,2-Hexanediol
Skin ConditioningPEG-100 Stearate
Disodium EDTA
Water, Ethyl Macadamiate, Dimethicone, Behenoxy Dimethicone, Glyceryl Stearate Se, Lysozyme, Cocoyl Argininamide, Salicylic Acid, Sodium Hyaluronate, Glyceryl Stearate, Juniperus Communis Wood Oil, Tocopheryl Acetate, Lactobacillus Ferment Lysate, Decylene Glycol, Butylene Glycol, Propanediol, Mirabilis Jalapa Extract, Sodium Carboxymethyl Betaglucan, Aloe Barbadensis Leaf Juice, Polyglyceryl-10 Laurate, Capryloyl Glycine, Cocoglycerides, Maltodextrin, Syringa Vulgaris Extract, Beta-Glucan, Hydroxyethylcellulose, Myristoyl Tetrapeptide-13, Myristoyl Pentapeptide-16, Caprylyl Glycol, 1,2-Hexanediol, PEG-100 Stearate, Disodium EDTA
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterDimethicone is a type of synthetic silicone created from natural materials such as quartz.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
- It has mild preservative properties.
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Beta-Glucan is a polysaccharide. It can be derived from the cell walls of seaweed, oats, yeast, and fungi. It hydrates the skin and helps boost your skin's natural barrier.
As an antioxidant, beta-glucan helps fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
Studies show this ingredient may be an effective wrinkle reducer as it can deeply penetrate into skin. It has also been show to help with wound healing.
Learn more about Beta-GlucanIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
ZO Skin Health Growth Factor Serum 34 ingredients
Hydropeptide Clear Rescue Skin Refining Serum 32 ingredients
Reviews
Here's what our community thinks
ZO Skin Health Growth Factor Serum 34 ingredients
TL;DR: Very soothing, VERY expensive, but works VERY well. Strong perfume smell you need to get used to.
...This works and I'm MAD about it.
I got suckered into this at my plastic surgeon's office during a laser consult by the esthetician, and...$168 later walked out with it thinking "WHAT HAVE I DONE?" Committed, I begrudgingly tried this praying I'd hate it so I wouldn't have to repurchase Show more
