This anti-aging serum is formulated around Sodium Hyaluronate and Copper Tripeptide-1 to soften the look of wrinkles and hydrate skin.
This anti-aging serum is formulated around Sh-Oligopeptide-1 to soften the look of wrinkles.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningMethylpropanediol
SolventButylene Glycol
Humectant1,2-Hexanediol
Skin ConditioningPolyglyceryl-10 Oleate
Skin ConditioningEthylhexylglycerin
Skin ConditioningSodium Hyaluronate
HumectantCopper Tripeptide-1
Skin ConditioningAdenosine
Skin ConditioningDisodium EDTA
ChelatingBiosaccharide Gum-1
HumectantBeta-Glucan
Skin ConditioningGlycine
BufferingTocopherol
AntioxidantSerine
MaskingGlutamic Acid
HumectantHouttuynia Cordata Extract
Skin ConditioningCentella Asiatica Extract
CleansingHydrolyzed Hyaluronic Acid
HumectantHydrolyzed Sodium Hyaluronate
Skin ConditioningHyaluronic Acid
HumectantHydroxypropyltrimonium Hyaluronate
Potassium Hyaluronate
Skin ConditioningAspartic Acid
MaskingLeucine
Skin ConditioningPentylene Glycol
Skin ConditioningAlanine
MaskingLysine
Skin ConditioningArginine
MaskingTyrosine
MaskingPhenylalanine
MaskingThreonine
Proline
Skin ConditioningValine
MaskingIsoleucine
Skin ConditioningSodium
Sodium Hyaluronate Crosspolymer
HumectantHistidine
HumectantMethionine
Skin ConditioningCysteine
AntioxidantSodium Acetylated Hyaluronate
HumectantPhosphatidylcholine
EmulsifyingAcetyl Hexapeptide-8
HumectantSh-Oligopeptide-1
Skin ConditioningOligopeptide-29
AntioxidantOligopeptide-32
AntiseborrhoeicPalmitoyl Pentapeptide-4
Skin ConditioningSh-Polypeptide-1
Skin ConditioningSh-Oligopeptide-2
Skin ConditioningSh-Polypeptide-22
Skin ConditioningPhenoxyethanol
PreservativeWater, Methylpropanediol, Butylene Glycol, 1,2-Hexanediol, Polyglyceryl-10 Oleate, Ethylhexylglycerin, Sodium Hyaluronate, Copper Tripeptide-1, Adenosine, Disodium EDTA, Biosaccharide Gum-1, Beta-Glucan, Glycine, Tocopherol, Serine, Glutamic Acid, Houttuynia Cordata Extract, Centella Asiatica Extract, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Potassium Hyaluronate, Aspartic Acid, Leucine, Pentylene Glycol, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Threonine, Proline, Valine, Isoleucine, Sodium, Sodium Hyaluronate Crosspolymer, Histidine, Methionine, Cysteine, Sodium Acetylated Hyaluronate, Phosphatidylcholine, Acetyl Hexapeptide-8, Sh-Oligopeptide-1, Oligopeptide-29, Oligopeptide-32, Palmitoyl Pentapeptide-4, Sh-Polypeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-22, Phenoxyethanol
Water
Skin ConditioningButylene Glycol
HumectantSh-Oligopeptide-1
Skin ConditioningSh-Polypeptide-1
Skin ConditioningVaccinium Angustifolium Fruit Extract
Skin ProtectingLecithin
EmollientSorbitan Sesquioleate
Emulsifying1,2-Hexanediol
Skin ConditioningCaprylyl Glycol
EmollientPEG-60 Hydrogenated Castor Oil
EmulsifyingGlycerin
HumectantChlorphenesin
AntimicrobialGuaiazulene
AntimicrobialEthylhexylglycerin
Skin ConditioningAdenosine
Skin Conditioning
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Learn more about AdenosineButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about Ethylhexylglycerinsh-Oligopeptide-1 is a peptide found naturally in our bodies. Peptides are the building blocks for collagen and elastin in our skin.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
Studies find EGF help with:
In South Korea and China, EGF is considered a controversial ingredient. The South Korean Ministry of Food and Drug Safety has cracked down on companies with products including EGF due to false advertisement claims.
According to Dr. Zoe Draelos, growth factors have some drawbacks:
There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Learn more about Sh-Oligopeptide-1Sh-Polypeptide-1 is a signal peptide that tells our cells to create more fibroblast cells. Fibroblasts maintain skin structure and plays a role in wound healing.
It is important to note this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water