This anti-aging serum is formulated around Niacinamide and Adenosine to soften the look of wrinkles and refine skin texture.
This anti-aging serum is formulated around Niacinamide and Sodium DNA to soften the look of wrinkles and strengthen the skin barrier.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Solanum Lycopersicum Fruit
EmollientWater
Skin ConditioningButylene Glycol
HumectantGlycereth-26
HumectantGlycerin
Humectant1,2-Hexanediol
Skin ConditioningNiacinamide
SmoothingDiethoxyethyl Succinate
SolventNicotinamide Mononucleotide
AntioxidantC12-14 Alketh-12
EmulsifyingGlyceryl Glucoside
HumectantAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingAllantoin
Skin ConditioningGardenia Florida Fruit Extract
Skin ConditioningXanthan Gum
EmulsifyingEthylhexylglycerin
Skin ConditioningDextrin
AbsorbentDipotassium Glycyrrhizate
HumectantTromethamine
BufferingSodium Polyacrylate
AbsorbentAdenosine
Skin ConditioningDisodium EDTA
Nicotinamide Adenine Dinucleotide
Skin ConditioningPentylene Glycol
Skin ConditioningLecithin
EmollientResveratrol
AntioxidantSodium Phosphate
BufferingAcetyl Hexapeptide-8
HumectantCopper Tripeptide-1
Skin ConditioningPalmitoyl Pentapeptide-4
Skin ConditioningAcetyl Tetrapeptide-5
HumectantCollagen
MoisturisingNonapeptide-1
Skin ConditioningPalmitoyl Hexapeptide-12
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningPalmitoyl Tripeptide-1
Skin ConditioningDipeptide Diaminobutyroyl Benzylamide Diacetate
Skin ConditioningDipeptide-2
Skin ConditioningHexapeptide-11
Skin ConditioningHexapeptide-9
Skin ConditioningPalmitoyl Tripeptide-5
Skin ConditioningPentapeptide-3
Skin ConditioningTripeptide-1
Skin ConditioningSolanum Lycopersicum Fruit, Water, Butylene Glycol, Glycereth-26, Glycerin, 1,2-Hexanediol, Niacinamide, Diethoxyethyl Succinate, Nicotinamide Mononucleotide, C12-14 Alketh-12, Glyceryl Glucoside, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Allantoin, Gardenia Florida Fruit Extract, Xanthan Gum, Ethylhexylglycerin, Dextrin, Dipotassium Glycyrrhizate, Tromethamine, Sodium Polyacrylate, Adenosine, Disodium EDTA, Nicotinamide Adenine Dinucleotide, Pentylene Glycol, Lecithin, Resveratrol, Sodium Phosphate, Acetyl Hexapeptide-8, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Acetyl Tetrapeptide-5, Collagen, Nonapeptide-1, Palmitoyl Hexapeptide-12, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Dipeptide-2, Hexapeptide-11, Hexapeptide-9, Palmitoyl Tripeptide-5, Pentapeptide-3, Tripeptide-1
Water
Skin ConditioningGlycerin
HumectantButylene Glycol
HumectantPropanediol
Solvent1,2-Hexanediol
Skin ConditioningNiacinamide
SmoothingPanthenol
Skin ConditioningNicotinamide Mononucleotide
AntioxidantHydroxyethylcellulose
Emulsion StabilisingSuccinic Acid
BufferingArginine
MaskingAmmonium Acryloyldimethyltaurate/Vp Copolymer
Carbomer
Emulsion StabilisingEthylhexylglycerin
Skin ConditioningGlyceryl Acrylate/Acrylic Acid Copolymer
HumectantDipotassium Glycyrrhizate
HumectantAllantoin
Skin ConditioningXanthan Gum
EmulsifyingAdenosine
Skin ConditioningGlutathione
Dextrin
AbsorbentTheobroma Cacao Extract
Skin Conditioning3-O-Ethyl Ascorbic Acid
Skin ConditioningCI 75470
Cosmetic ColorantPinus Pinaster Bark Extract
AntioxidantPolysorbate 60
EmulsifyingSodium DNA
Skin ConditioningTrisodium Phosphate
BufferingThioctic Acid
AntioxidantWater, Glycerin, Butylene Glycol, Propanediol, 1,2-Hexanediol, Niacinamide, Panthenol, Nicotinamide Mononucleotide, Hydroxyethylcellulose, Succinic Acid, Arginine, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Carbomer, Ethylhexylglycerin, Glyceryl Acrylate/Acrylic Acid Copolymer, Dipotassium Glycyrrhizate, Allantoin, Xanthan Gum, Adenosine, Glutathione, Dextrin, Theobroma Cacao Extract, 3-O-Ethyl Ascorbic Acid, CI 75470, Pinus Pinaster Bark Extract, Polysorbate 60, Sodium DNA, Trisodium Phosphate, Thioctic Acid
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Learn more about AdenosineAllantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Learn more about AllantoinButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolDextrin is a starch-derived polysaccharide. It's made by partially breaking down corn, potato, or other plant starches.
Think of it as "half-processed" starch; it's less complex than the original but not fully broken down into sugar like maltodextrin.
In cosmetics, it mainly functions as a bulking agent, viscosity controller, binder, and absorbent. It helps thicken products, stabilize powders, and get certain textures a less "wet" feel.
This ingredient has a pretty solid safety profile; it's recognized as a safe food additive and its large molecular size means it doesn't meaningfully penetrate skin.
Human repeat insult patch tests using a rinse-off facial product containing 42.69% dextrin found no skin irritation or sensitization in 54 subjects.
Typical real-world usage is much lower: usually under 1% as a texture modifier and up to 40% in masks (rinse off products use less).
Learn more about DextrinDipotassium Glycyrrhizate comes from licorice root.
Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.
One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.
Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.
Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.
Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.
Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.
Learn more about Dipotassium GlycyrrhizateEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideNicotinamide Mononucleotide, or NMN, is a nucleotide derived from niacin and a precursor to NAD+.
NAD+ is a coenzyme that is used for cellular energy production, DNA repair, and signaling protein activation. These all slow down as we age and as NAD+ levels decline.
In lab and animal studies, NMN has demonstrated:
This ingredient also breaks down into niacinamide even as it degrades.
There are two major caveats to this ingredient:
1) It is not stable and degrades quickly in water-based formulations.
2) Most of the skin data is still prelinical (cell and animal studies) and human clinical trials are still limited.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan Gum