Dermatouch Vitamin C 10% Serum Versus Dot & Key Skincare 10% Vitamin C+E & 5% Niacinamide Face Serum
This brightening serum is formulated around 3-O-Ethyl Ascorbic Acid and Acetyl Glucosamine to brighten dull-looking skin and fade the look of dark spots.
This brightening serum is formulated around 3-O-Ethyl Ascorbic Acid and Niacinamide to brighten dull-looking skin and fade the look of dark spots.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin Conditioning3-O-Ethyl Ascorbic Acid
Skin Conditioning
Niacinamide
Smoothing
Glycerin
Humectant
Ethoxydiglycol
HumectantPropanediol
Solvent
Butylene Glycol
Humectant
Ethylhexylglycerin
Skin ConditioningPhenoxyethanol
Preservative
Tocopheryl Acetate
Antioxidant
Ferulic Acid
Antimicrobial
Citric Acid
Buffering
Xanthan Gum
EmulsifyingHydroxyethylcellulose
Emulsion StabilisingDisodium EDTA
Sodium Gluconate
Skin ConditioningAllantoin
Skin Conditioning
Sodium Hyaluronate
Humectant
Alpha-Arbutin
Antioxidant
Laminaria Digitata Extract
Skin Protecting
Cetyl-Pg Hydroxyethyl Palmitamide
Skin ConditioningCeramide AP
Skin Conditioning
Citrus Aurantium Dulcis Fruit Extract
MaskingTerminalia Ferdinandiana Fruit Extract
Antioxidant
Cucurbita Pepo Fruit Extract
Skin Conditioning
Water, 3-O-Ethyl Ascorbic Acid, Niacinamide, Glycerin, Ethoxydiglycol, Propanediol, Butylene Glycol, Ethylhexylglycerin, Phenoxyethanol, Tocopheryl Acetate, Ferulic Acid, Citric Acid, Xanthan Gum, Hydroxyethylcellulose, Disodium EDTA, Sodium Gluconate, Allantoin, Sodium Hyaluronate, Alpha-Arbutin, Laminaria Digitata Extract, Cetyl-Pg Hydroxyethyl Palmitamide, Ceramide AP, Citrus Aurantium Dulcis Fruit Extract, Terminalia Ferdinandiana Fruit Extract, Cucurbita Pepo Fruit Extract
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
3-O-Ethyl Ascorbic Acid is one of the most popular "stable" vitamin C derivatives in skincare.
Plain ascorbic acid is fantastic but notoriously fragile; it browns, oxidizes, and loses potency fast. So attaching an ethyl group to the third carbon of the molecule gives it some cool perks:
In a formula, it does the 3 classic vitamin C jobs: it acts as an antioxidant, helps brighten skin tone by inhibiting tyrosinase, and supports collagen.
The evidence is reasonably solid for a cosmetic ingredient; Liao and colleagues (2018) showed it's significantly more stable than ascorbic acid while still being effective.
A 2021 study by Zerbinati and colleagues tested a serum with 30% 3-O-ethyl-l-ascorbic acid and 1% lactic acid significantly increased collagen production, reduced UVB-induced DNA damage, and decreased melanin on a reconstructed pigmented skin model.
Typical real world usage sits around 0.5-5% (and 1-2% is common for daily serums).
Amounts up to 30% have been shown to be non-irritating on human skin samples, but two isolated cases reported allergic contact dermatitis so a patch test is sensible if you have reactive skin.
Learn more about 3-O-Ethyl Ascorbic AcidEthoxydiglycol (aka Diethylene Glycol Monoethyl Ether) is one of the cosmetic world's quiet problem solvers.
In a formula, it is a solvent that dissolves tricky ingredients that don't want to mix in and helps spread ingredients evenly across your skin without leaving a greasy or sticky feeling
This makes it great for hard-to-dissolve actives like vitamin C, benzoyl peroxide, and self-tanner DHA.
It also has mild humectant and penetration enhancer abilities so it can help some actives absorb a little deeper.
The penetration boost is backed by lab research: studies using human skin samples found it improved how well an active dissolves into the upper layer of skin rather than tearing down your skin barrier. Reviews of its mechanism also describe it interacting gently with the lipids and water in your outermost layer of skin.
Just know this penetration-enhancing effect is not universal. It helps a lot in some formulas and did very little in others (so the benefit really depends on the specific product).
Safety-wise, the evidence is reassuring. The Cosmetic Ingredient Review Expert Panel reviewed it and concluded it's safe for use in cosmetics and recognized it as non-irritating, non-sensitizing, and non-comedogenic in skincare.
Typical leave-on skincare usage lands around 1-10%. The EU has sets caps of 2.6% in non-spray products, 10% in rinse-offs, 7% in oxidative hair dye, and 5% in non-oxidative hair dye.
Learn more about EthoxydiglycolGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinHydroxyethylcellulose is used to improve the texture of products. It is created from a chemical reaction involving ethylene oxide and alkali-cellulose. Cellulose is a sugar found in plant cell walls and help give plants structure.
This ingredient helps stabilize products by preventing ingredients from separating. It can also help thicken the texture of a product.
This ingredient can also be found in pill medicines to help our bodies digest other ingredients.
Learn more about HydroxyethylcellulosePhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolThis is the synthetic salt of gluconic acid, a form of PHA and mild exfoliant.
It is mainly used to stabilize oil and butter formulations from going bad. Sodium gluconate is a humectant, pH regulator, and chelating agent.
Chelating agents help neutralize unwanted metals from affecting the formulation.
Sodium gluconate is water-soluble.
Learn more about Sodium GluconateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan Gum
