Explore Routine Login
Versus

Avène Cleanance Comedomed Localised Drying Emulsion Versus La Roche-Posay Effaclar Duo+ Global Acne Treatment

Facial Treatment
Facial Treatment
French Brand France
French Brand France

Overview

What they are

These products are both reef safe facial treatments. They have a total of 3 ingredients in common

Suited For

They're both likely to be good for fighting acne, dry skin, brightening skin and scar healing

Free From

They both do not contain any common allergens, parabens or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Cleanance Comedomed Localised Drying Emulsion
Caprylic Acid Cleansing, Emulsifying, Masking
1 / 3

Caprylic Acid is a fatty acid commonly found in plant oils, such as palm and coconut oils.

1 Com. / 3 Irr.
Isododecane Emollient, Solvent

Isododecane is a fragrance, emollient, and solvent.

Disliked Full details ->
Glycolic Acid Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation IconMay worsen Rosacea Icon
AHAAHA Icon 7 Benefits 2 Concerns

Glycolic Acid is arguably the most famous AHA with a ton of research to back up its benefits.

Isopropyl Alcohol Solvent
0 / 0 Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon
AlcoholAlcohol Icon 5 Concerns

Isopropyl Alcohol is more commonly known as rubbing alcohol. It is most commonly used as a solvent, meaning it helps other ingredients dissolve.

0 Com. / 0 Irr.
Very Disliked Full details ->
Peg-6 Humectant, Solvent

We don't have a description for Peg-6.

Unknown Full details ->
Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

2-Hydroxyethyl Acrylate

We don't have a description for 2-Hydroxyethyl Acrylate.

Disliked Full details ->
Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

Glyceryl Stearate Emollient, Emulsifying
1 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Glyceryl Stearate is a mix of glycerin and stearic acid.

1 Com. / 0 Irr.
Disliked Full details ->
Peg-100 Stearate
0 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Peg-100 Stearate is an emollient and emulsifier. PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.

0 Com. / 0 Irr.
Very Disliked Full details ->
Polymethyl Methacrylate

We don't have a description for Polymethyl Methacrylate.

Disliked Full details ->
Arachidyl Alcohol Emollient, Emulsion Stabilising

Arachidyl Alcohol is a fatty alcohol made from peanut oil. It is an emollient, emulsifier, and thickener.

Very Disliked Full details ->
Arachidyl Glucoside Emulsifying

We don't have a description for Arachidyl Glucoside.

Disliked Full details ->
Behenyl Alcohol Emollient, Emulsion Stabilising
Fatty Alcohol Icon
Fatty AlcoholFatty Alcohol Icon

A type of fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product. They are usually derived from natural fats and oils and therefore do not have the same drying or irritating effect as traditional alcohols.

Disliked Full details ->
Helianthus Annuus Seed Oil Emollient, Masking, Skin Conditioning
0 / 0 Oil IconHelps hydrate Dry Skin IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon
OilOil Icon Helps hydrate Dry SkinHelps hydrate Dry Skin Icon 2 Concerns

Helianthus Annuus Seed Oil is the oil derived from the seeds of a Sunflower. Sunflower seed oil is non-fragrant. It is an emollient, meaning it helps to soften the skin.

0 Com. / 0 Irr.
Disliked Full details ->
Polysorbate 60 Emulsifying
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.

Very Disliked Full details ->
CI 17200 Cosmetic Colorant
1 / 2

Ci 17200 is a synthetic reddish-purple dye.

1 Com. / 2 Irr.
Unknown Full details ->
Retinal Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconCan worsen Dry Skin IconMay cause irritation IconMay worsen Rosacea Icon
RetinoidRetinoid Icon 7 Benefits 3 Concerns

Retinal is a form of retinoid. Retinoids are the gold-standard class of anti-aging ingredients.

Silybum Marianum Fruit Extract Skin Conditioning

We don't have a description for Silybum Marianum Fruit Extract.

Unknown Full details ->
Sorbitan Isostearate Emulsifying
1-2 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Sorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.

1-2 Com. / 0 Irr.
Very Disliked Full details ->
Tocopherol Antioxidant, Masking, Skin Conditioning
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon 4 Benefits May cause irritationMay cause irritation Icon

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

0-3 Com. / 0-3 Irr.
Effaclar Duo+ Global Acne Treatment
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0 Silicon Icon
SiliconSilicon Icon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

1 Com. / 0 Irr.
Very Disliked Full details ->
Isocetyl Stearate Emollient, Skin Conditioning
0-1 / 0 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon
3 Concerns

Isocetyl Stearate is an ester of isocetyl alcohol and stearic acid.

0-1 Com. / 0 Irr.
Unknown Full details ->
Isopropyl Lauroyl Sarcosinate Skin Conditioning

We don't have a description for Isopropyl Lauroyl Sarcosinate.

Unknown Full details ->
Silica Abrasive, Absorbent
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon
ExfoliantExfoliant Icon 2 Concerns

Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.

Disliked Full details ->
Ammonium Polyacryloyldimethyl Taurate Emulsion Stabilising

Ammonium Polyacryloyldimethyl Taurate is a polymer made from ammonium salts. It helps add stability and texture to a product.

Methyl Methacrylate Crosspolymer

We don't have a description for Methyl Methacrylate Crosspolymer.

Disliked Full details ->
Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

Poloxamer 338 Emulsifying

We don't have a description for Poloxamer 338.

Unknown Full details ->
Polysorbate 80 Emulsifying
0 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon
2 Concerns

Polysorbate 80 is a surfactant and emulsifier. It is used to keep ingredients together, and prevent oils and waters from separating.

0 Com. / 0 Irr.
Very Disliked Full details ->
Mannose Humectant

We don't have a description for Mannose.

Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Zinc PCA Humectant, Skin Conditioning
Good for Scar Healing IconHelps fight Acne Icon
2 Benefits

Zinc PCA (or "zinc salt") differs slightly from zinc itself. PCA stands for pyrrolidone carboxylic acid. However, Zinc PCA comes from zinc.

Isohexadecane Emollient, Skin Conditioning, Solvent

Isohexadecane is added to enhance texture, emulsify, and to help cleanse. It is an isoparrafin. It is a component of petrolatum.

2-Oleamido-1,3-Octadecanediol Skin Conditioning

We don't have a description for 2-Oleamido-1,3-Octadecanediol.

Unknown Full details ->
Capryloyl Salicylic Acid Skin Conditioning

Capryloyl Salicylic Acid comes from salicylic acid, the famous acne-fighting BHA.

Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Piroctone Olamine Preservative
Preservative Icon
PreservativePreservative Icon

Piroctone Olamine is a preservative.

Myristyl Myristate Emollient, Skin Conditioning
0-5 / 2 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon
3 Concerns

Myristyl Myristate is created from the fatty acids of myristyl alcohol and myristic acid. In skincare, it is an emollient and texture enhancer.

0-5 Com. / 2 Irr.
Very Disliked Full details ->
Acrylamide

We don't have a description for Acrylamide.

Unknown Full details ->
Sorbitan Oleate Emulsifying
3 / 0 Bad for Acne Prone Skin IconNot safe for Fungal Acne Icon
2 Concerns

Sorbitan Oleate is created from compounds in oleic acid and sorbitol. It is used to stabilize a product by preventing ingredients from separating.

3 Com. / 0 Irr.
Very Disliked Full details ->
Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Potassium Cetyl Phosphate Emulsifying

Potassium Cetyl Phosphate is the potassium salt of a mixture. This mixture consists of the esters from phosphoricacid and cetyl alcohol.

Vitreoscilla Ferment Skin Conditioning

Vitreoscilla Ferment is a probiotic derived from the Vitreoscilla bacteria.

Aluminum Starch Octenylsuccinate Absorbent

Aluminum Starch Octenylsuccinate is a synthetic powder used as an absorbent, thickener, and anti-caking agent.

Disliked Full details ->
Glyceryl Stearate Se Emulsifying
3 / 2 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Glyceryl Stearate Se is a self-emulsifying (SE) form of glyceryl stearate. Self-emusifying means this ingredient automatically blends with water. It is an emulsifier, emollient, and cleansing agent.

3 Com. / 2 Irr.
Very Disliked Full details ->
Parfum Masking, Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon
FragranceFragrance Icon 2 Concerns

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Very Disliked Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Buffering
Mixed

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Learn more about Sodium Hydroxide

Ingredient Ratings

Here's what our community thinks of the ingredients in these products.

Cleanance Comedomed Localised Drying Emulsion
5
2
12
3
liked
mixed
disliked
not rated
Effaclar Duo+ Global Acne Treatment
10
2
11
5
liked
mixed
disliked
not rated

When to use

7 Routines
43% use in am
57% use in pm
100% use every day
263 Routines
44% use in am
56% use in pm
86% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Avène Cleanance Comedomed Localised Drying Emulsion 22 ingredients

Cleanance Comedomed Localised Drying Emulsion hasn't been rated yet.
Rate it now

La Roche-Posay Effaclar Duo+ Global Acne Treatment 28 ingredients

4.0 /5
from 2 ratings
YousifShamoon's avatar

YousifShamoon

1 year ago · Combination Skin
Review

interesting to say the least
no one warned me about the purge i was gonna get from this. the crease on my nose and my chin turned red and were...

interesting to say the least
no one warned me about the purge i was gonna get from this. the crease on my nose and my chin turned red and were peeling for weeks but i think it paid off in the end. it handled my sebum production and pimples very well, but unfortunately i can't say the same for my blackheads and whiteheads, which remained unbothered by this product. another thing i wasn't warned about when i used this is that it is not hydrating enough to be used as a moisturiser. i only realised this when i switched to byoma's gel cream moisturiser but you have to use this as a facial or spot treatment and follow up with a proper moisturiser. overall i liked this but i had to stop using it because it was constantly sold out and i think it is so expensive right now and i also needed to stop using benzyl peroxide so i can switch to retinol.