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Updated on June 25, 2024

Overview

What they are

These products are both reef safe ampoules. They have a total of 12 ingredients in common

Cool Features

They both contain hyaluronic acid, niacinamide and peptides

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

AMPLE:N Peptide Shot Ampoule 2x
Isntree TW-Real Bifida Ampoule

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Ingredients Side-by-side

found in both products
Peptide Shot Ampoule 2x
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Dipropylene Glycol Masking, Solvent

Dipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.

Disliked Full details ->
1,2-Hexanediol Skin Conditioning, Solvent

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Polyglycerin-3 Humectant

Polyglycerin-3 is a 3-unit glycerin polymer.

Adenosine Skin Conditioning
Helps with Anti-Aging IconGood for Scar Healing Icon
2 Benefits

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Beta-Glucan Skin Conditioning
Helps reduce Skin Redness Icon
Helps reduce Skin RednessHelps reduce Skin Redness Icon

Beta-Glucan is a polysaccharide. It can be derived from the cell walls of seaweed, oats, yeast, and fungi.

Arginine Masking, Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

Dipotassium Glycyrrhizate Humectant, Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon
3 Benefits

Dipotassium Glycyrrhizate comes from licorice root.

Hyaluronic Acid Humectant, Moisturising, Skin Conditioning
Hyaluronic Acid IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation Icon
Hyaluronic AcidHyaluronic Acid Icon 4 Benefits May cause irritationMay cause irritation Icon

Hyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.

Mallotus Japonicus Leaf Extract Antimicrobial, Antioxidant, Skin Protecting
Antioxidant Icon
AntioxidantAntioxidant Icon

Mallotus Japonicus Leaf Extract is an antioxidant.

Unknown Full details ->
Yeast Extract Skin Conditioning, Skin Protecting

We don't have a description for Yeast Extract.

Helichrysum Arenarium Extract Antiseborrhoeic, Skin Conditioning, Soothing

We don't have a description for Helichrysum Arenarium Extract.

Unknown Full details ->
Copper Tripeptide-1 Skin Conditioning
Peptide IconHelps with Anti-Aging Icon
PeptidePeptide Icon Helps with Anti-AgingHelps with Anti-Aging Icon

Copper Tripeptide-1 is a peptide naturally found in body fluids. Peptides are building blocks for protein.

Acetyl Tetrapeptide-2 Skin Conditioning
Peptide Icon
PeptidePeptide Icon

Acetyl Tetrapeptide-2 is a peptide.

Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Dextran

We don't have a description for Dextran.

Unknown Full details ->
Hydroxyethylcellulose Emulsion Stabilising, Stabilising

Hydroxyethylcellulose is used to improve the texture of products. It is created from a chemical reaction involving ethylene oxide and alkali-cellulose. Cellulose is a sugar found in plant cell walls and help give plants structure.

Caramel Cosmetic Colorant, Masking

We don't have a description for Caramel.

Glyceryl Acrylate/Acrylic Acid Copolymer Humectant

Glyceryl Acrylate/Acrylic Acid Copolymer is made up of glycerin and polyacrylic acid. It helps hydrate your skin as a humectant.

Trifluoroacetyl Tripeptide-2 Skin Conditioning, Skin Protecting
Peptide Icon
PeptidePeptide Icon

Trifluoroacetyl Tripeptide-2 is a peptide.

Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Boron Nitride Absorbent, Skin Conditioning

Boron Nitride is compound consisting of boron and nitrogen. It is used to absorb oil and modify adherence/ slip in products.

Pvm/Ma Copolymer Emulsion Stabilising

We don't have a description for Pvm/Ma Copolymer.

Unknown Full details ->
Agar Masking

Agar is the vegan substitute for animal-gelatin. It helps thicken and improve the texture of cosmetics.

Gellan Gum

Gellan Gum is a high-molecular weight heteropolysaccharide gum. It is created by the process of pure-culture fermentation with the bacterium Pseudomonas elodea.

Disliked Full details ->
Calcium Alginate Masking

We don't have a description for Calcium Alginate.

Unknown Full details ->
Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Glucosylrutin Antioxidant
Antioxidant Icon
AntioxidantAntioxidant Icon

Glucosylrutin is an antioxidant.

Unknown Full details ->
Palmitoyl Tripeptide-5 Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Palmitoyl Tripeptide-5 isn't fungal acne safe and is a peptide.

Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate Skin Conditioning

We don't have a description for Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate.

Magnesium Chloride

We don't have a description for Magnesium Chloride.

Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
TW-Real Bifida Ampoule
Bifida Ferment Lysate Skin Conditioning
Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.

Dipropylene Glycol Masking, Solvent

Dipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.

Disliked Full details ->
Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Lactobacillus/Pumpkin Ferment Extract Skin Conditioning

We don't have a description for Lactobacillus/Pumpkin Ferment Extract.

Lactobacillus/Soybean Ferment Extract Skin Conditioning

This ingredient is created by fermenting soybean extract with the bacteria, lactobacillus.

Rice Ferment Filtrate Skin Conditioning
Helps with Anti-Aging IconGood for Dark Spots Icon
2 Benefits

Rice Ferment Filtrate is created by fermenting rice, or oryza sativa. A common name for this ingredient is sake, the traditional Japanese fermented rice alcoholic beverage.

Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Hydrolyzed Collagen Emollient, Humectant, Skin Conditioning
Helps with Anti-Aging Icon
Helps with Anti-AgingHelps with Anti-Aging Icon

Hydrolyzed collagen has a misleading name because it is actually a mixture of various proteins/peptides. This ingredient has skin hydrating properties.

Salix Alba Bark Extract Astringent, Skin Conditioning, Soothing
Good for Oily Skin Icon
Good for Oily SkinGood for Oily Skin Icon

Salix Alba Bark Extract comes from the white willow tree, which is native to Europe and Central Asia.

Origanum Vulgare Leaf Extract Skin Conditioning

We don't have a description for Origanum Vulgare Leaf Extract.

Unknown Full details ->
Cinnamomum Zeylanicum Bark Extract Antimicrobial, Antioxidant, Astringent
Antioxidant IconFragrance Icon
AntioxidantAntioxidant Icon FragranceFragrance Icon

Cinnamomum Zeylanicum Bark Extract is an antioxidant and is a fragrance.

Disliked Full details ->
Portulaca Oleracea Extract Skin Conditioning

Portulaca Oleracea Extract is an extract of the whole plant of the Purslane, Portulaca oleracea L., Portulacaceae. It has anti-inflammatory, antioxidant, and hydrating properties.

Chamaecyparis Obtusa Leaf Extract Skin Conditioning

We don't have a description for Chamaecyparis Obtusa Leaf Extract.

Beta-Glucan Skin Conditioning
Helps reduce Skin Redness Icon
Helps reduce Skin RednessHelps reduce Skin Redness Icon

Beta-Glucan is a polysaccharide. It can be derived from the cell walls of seaweed, oats, yeast, and fungi.

Palmitoyl Oligopeptide Cleansing, Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Palmitoyl Oligopeptide is a form of peptide. It is created by blending peptides with palmitic acid. Peptides are building blocks for protein.

Copper Tripeptide-1 Skin Conditioning
Peptide IconHelps with Anti-Aging Icon
PeptidePeptide Icon Helps with Anti-AgingHelps with Anti-Aging Icon

Copper Tripeptide-1 is a peptide naturally found in body fluids. Peptides are building blocks for protein.

Acetyl Hexapeptide-8 Humectant, Skin Conditioning
Peptide Icon
PeptidePeptide Icon

Acetyl Hexapeptide-8 is a peptide. A common name for this peptide is Argireline.

Allantoin Skin Conditioning, Skin Protecting, Soothing
0 / 0 Helps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon
3 Benefits

Allantoin plays a role in soothing and moisturizing the skin. Because of this, it is often added to products with strong active ingredients.

0 Com. / 0 Irr.
Hydroxyethylcellulose Emulsion Stabilising, Stabilising

Hydroxyethylcellulose is used to improve the texture of products. It is created from a chemical reaction involving ethylene oxide and alkali-cellulose. Cellulose is a sugar found in plant cell walls and help give plants structure.

Panthenol Skin Conditioning
0 / 0 Helps reduce irritation Icon
Helps reduce irritationHelps reduce irritation Icon

Panthenol is a common ingredient that helps hydrate and soothe the skin. It can be found naturally in our skin and hair.

0 Com. / 0 Irr.
Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Arginine Masking, Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Scutellaria Baicalensis Root Extract Astringent, Humectant, Soothing
Good for Scar Healing Icon
Good for Scar HealingGood for Scar Healing Icon

Scutellaria Baicalensis Root Extract comes from the Baikal skullcap or Chinese skullcap plant. This plant is native to Northeast Asia and can be found in China, Mongolia, Korea, and Siberia.

Illicium Verum Fruit Extract Perfuming, Skin Conditioning
Fragrance Icon
FragranceFragrance Icon

Illicium Verum Fruit Extract is a fragrance.

Adenosine Skin Conditioning
Helps with Anti-Aging IconGood for Scar Healing Icon
2 Benefits

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

1,2-Hexanediol Skin Conditioning, Solvent

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Masking, Skin Conditioning
Mixed

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.

Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.

Masking, Solvent
Disliked

Dipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.

Dipropylene Glycol helps dissolve and evenly distribute ingredients. It also helps decrease viscosity and thin out texture.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Learn more about Dipropylene Glycol
Skin Conditioning, Solvent
Mixed

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

In products that are water-based, this ingredient can help stabilize perfumes and fragrances. It can also help make the texture of products softer and more smooth.

Smoothing
Loved

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide
Skin Conditioning
Loved

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine
Skin Conditioning
Loved

Beta-Glucan is a polysaccharide. It can be derived from the cell walls of seaweed, oats, yeast, and fungi.

Beta-Glucan is a humectant, meaning it can hold large amounts of water. This helps hydrate the skin. It also helps boost your skin's natural barrier.

Beta-Glucan has antioxidant properties. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

Studies show Beta-Glucan may be an effective wrinkle reducer as it can deeply penetrate into skin. It has also been show to help with wound healing.

Learn more about Beta-Glucan
Masking, Skin Conditioning
Mixed

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

As a cosmetic ingredient, Arginine has antioxidant properties and can also help repair damaged skin. This ingredient is derived either synthetically or from animals.

Arginine isn't fungal acne safe when used in the presence of other lipids (fats, fatty acids, oils, esters, etc). Oils and fats occur naturally within the skin, so take caution when using Arginine if you're prone to fungal acne.

Learn more about Arginine
Skin Conditioning
Loved

Copper Tripeptide-1 is a peptide naturally found in body fluids. Peptides are building blocks for protein.

Studies show this ingredient tells our body to create more collagen and elastin. Collagen is a protein that makes connective tissue. Elastin is the protein responsible for giving our skin elasticity. Our bodies start to slow down collagen and elastin production with age.

Boosting collagen and elastin production can help create a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin. It's a win-win situation!

This ingredient helps with scar healing. This is because it breaks down damaged collagen, the main component of scar tissue. It may also help with reducing sunspots, acne scars, and uneven skin tone.

On top of all this, Copper Tripeptide-1 is also an antioxidant. Antioxidants help the body fight off free-radicals. Free radicals are molecules that damage our cells, such as pollution and tobacco smoke.

More benefits: Copper Tripeptide-1 helps maintain tissues in blood vessels and promote natural hyaluronic acid in skin.

Read more about other common types of peptides here:

Learn more about Copper Tripeptide-1
Emulsion Stabilising, Gel Forming
Disliked

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

Carbomer is commonly found in many types of cosmetics products. It is found to be safe in concentrations up to 15%. However, a high amount of carbomer can cause pilling or balling up of products. Most products contain 1% of less of carbomer.

Emulsion Stabilising, Stabilising
Mixed

Hydroxyethylcellulose is used to improve the texture of products. It is created from a chemical reaction involving ethylene oxide and alkali-cellulose. Cellulose is a sugar found in plant cell walls and help give plants structure.

Hydroxyethylcellulose helps stabilize products by preventing ingredients from separating. It can also help thicken the texture of a product.

This ingredient can also be found in pill medicines to help our bodies digest other ingredients.

Learn more about Hydroxyethylcellulose
Disliked

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA

Ingredient Ratings

Here's what our community thinks of the ingredients in these two products.

Peptide Shot Ampoule 2x
14
10
5
6
liked
mixed
disliked
not rated
TW-Real Bifida Ampoule
20
4
4
1
liked
mixed
disliked
not rated

When to use

7 Routines
43% use in am
57% use in pm
43% use every day
97 Routines
40% use in am
60% use in pm
89% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

AMPLE:N Peptide Shot Ampoule 2x 35 ingredients

Peptide Shot Ampoule 2x hasn't been rated yet.
Rate it now

Isntree TW-Real Bifida Ampoule 29 ingredients

5.0 /5
from 1 rating
Marifsts's avatar

Marifsts

10 months ago · Combination Skin
Review

Worthy a lot
I'm using as a dupe to Lancome Gentifique serum and I love it, my skin is soft and feels healthier, I can describe, but is a perfect dupe