VeraLab Siero Defence
A serum with 22 ingredients.
This barrier-repair serum is formulated around Centella Asiatica Leaf Extract and Chamomilla Recutita Flower Extract to strengthen the skin barrier and calm redness.
Worth noting
Contains Benzyl Alcohol, an EU-listed fragrance allergen.
We independently verify ingredients, backed by peer-reviewed research. Suggest an update.
What's inside
Ingredients List
Water
Skin ConditioningOlus Oil
EmollientCaprylic/Capric Triglyceride
MaskingIsostearyl Isostearate
EmollientGlycerin
HumectantSucrose Stearate
EmollientMicrocrystalline Cellulose
AbsorbentCentella Asiatica Leaf Extract
Skin ConditioningMentha Piperita Leaf Extract
Skin ConditioningChamomilla Recutita Flower Extract
MaskingEquisetum Arvense Extract
AstringentCitrus Aurantium Dulcis Peel Extract
Emulsion StabilisingRose Extract
Skin ConditioningAlthaea Officinalis Root Extract
Skin ConditioningUlmus Fulva Bark Extract
MoisturisingSymphytum Officinale Leaf Extract
Skin ConditioningParfum
MaskingBenzyl Alcohol
PerfumingXanthan Gum
EmulsifyingCellulose Gum
Emulsion StabilisingGlyceryl Laurate
EmollientCitric Acid
BufferingWater, Olus Oil, Caprylic/Capric Triglyceride, Isostearyl Isostearate, Glycerin, Sucrose Stearate, Microcrystalline Cellulose, Centella Asiatica Leaf Extract, Mentha Piperita Leaf Extract, Chamomilla Recutita Flower Extract, Equisetum Arvense Extract, Citrus Aurantium Dulcis Peel Extract, Rose Extract, Althaea Officinalis Root Extract, Ulmus Fulva Bark Extract, Symphytum Officinale Leaf Extract, Parfum, Benzyl Alcohol, Xanthan Gum, Cellulose Gum, Glyceryl Laurate, Citric Acid
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterOlus Oil is the INCI umbrella name for vegetable oil; this is an oil of plant origin made up mostly of fatty acid triglycerides.
The key thing to know is that it's a generic term rather than one specific oil: it refers to a vegetable oil or a blend of vegetable oils so its effect may vary depending on the sources used.
Functionally, it's an emollient that helps soften skin and works as a hydrator to prevent water loss.
This ingredient works well across a wide pH range and has a long shelf life.
Fungal acne:
Because olus oil is an undefined blend, its fungal acne safety depends entirely which oils are used. A Caprylic/Capric Triglyceride-based version would be fungal acne safe while a rapeseed blend will contain longer-chain fatty acids that Malassezia can feed on.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglycerideIsostearyl Isostearate is a plant-based and vegan emollient ester made by reacting Isostearyl Alcohol and Isostearic Acid.
It helps improve how the product spreads on skin, acts as a binding agent for makeup powders without modifying pigment color, and softens skin while helping it hold onto water.
This ingredient is very interesting as a hydrator; most moisturizers are either occlusives, humectants, or emollients. Isostearyl isostearate works through another route named "internal occlusion" by the head researcher.
Isostearyl isostearate nudges the skin's own lipids into a denser, more tightly packed arrangement. Packing the deeper layers of the stratum corneum together more efficiently means less water is able to escape.
This is a barrier-improving mechanism that hadn't been described before and plastic occlusion stress tests confirmed it improved the skin's water-permeability barrier function
Just one thing worth noting from the same review: this ingredient increased the penetration rate of a test drug through excised human skin. Though this ingredient is not classified as a penetration enhancer, it does interact with the barrier rather than sitting totally inert on top.
Fungal acne:
The Malassezia yeast feeds on fatty acids and esters in the C11-24 range. Since both halves of this molecules are C18, it may not be fungal acne safe.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinSucrose Stearate is derived from stearic acid and sucrose (sugar). It is an emollient and emulsifier.
As an emulsifier, it prevents oils and water from separating in a product. This property also makes it a surfactant and therefore a cleansing agent.
Microcrystalline Cellulose is another name for refined wood pulp. It is used as an emulsifier and mattifying ingredient. As an emulsifier, it helps keep ingredients together.
Centella Asiatica Leaf Extract comes from the leaves of an herb plant native to Southeast Asia. Centella Asiatica is rich in antioxidants and amino acids. It can help reduce irritation and soothe the skin.
Many active components found in centella asiatica, such as Madecassic Acid and Asiaticoside, encourage the skin to naturally produce hyaluronic acid. This helps keep our skin hydrated. Many of these components also show antioxidant activity and may help reduce the signs of aging.
Research shows centella asiatica can help increase Type I collagen production by increasing fibroblast production. Fibroblast helps form connective tissue.
The combination of all these properties makes centella asiatica leaf extract effective at soothing the skin.
Other components of centella asiatica leaf extract include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.
Recent studies found madecassoside may help prevent damage from UV rays by preventing UV-induced inflammation. Further research is needed.
This plant has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Learn more about Centella Asiatica Leaf ExtractMentha Piperita Leaf Extract is extract from peppermint leaves. It has a "cooling" sensory feel depending on what compounds are found in the extract.
Peppermint leaves contain polyphenols that antioxidant activity. In-vitro studies show anti-inflammatory and antimicrobial activity against some bacteria and fungi.
Evidence for mint as a "treatment" ingredient is limited and depends heavily on the specific extract type and concentration.
In large percentages, peppermint extract may sensitize the skin.
Learn more about Mentha Piperita Leaf ExtractChamomilla Recutita Flower Extract comes from the Chamomile flower.
Chamomile is rich in antioxidants and has anti-inflammatory properties. Several compounds found in chamomile help with soothing, such as bisbolol.
Antioxidant components in chamomile make it an effective ingredient to help slow the signs of aging. Antioxidants help fight free-radical molecules, or molecules that may damage your skin.
Essential oils from chamomile have been found to improve wound healing due to its antimicrobial properties.
Ancient Greeks and Egyptians used Chamomile to treat skin redness and dryness. Chamomile has also been used to help treat stomach issues.
Learn more about Chamomilla Recutita Flower ExtractThis botanical extract is also known as horsetail extract. It mainly acts as an emollient, skin soother, and astringent.
A study from 2023 found compounds in Equisetum Arvense showed significant anti-inflammatory effects in irritated keratinocytes (the main cell in your outermost layer of skin).
Another study using a cream with horsetail and soybean extract found 80% of participants showed at least a 26% improvement in forehead wrinkles after 8 weeks.
Animal research has shown topical Equisetum Arvense stimulated skin and tissue growth in mice.
The research so far is encouraging, but still in its early days. But it's a lovely supporting ingredient and can be a welcome addition to any routine.
Learn more about Equisetum Arvense ExtractCitrus Aurantium Dulcis Peel Extract comes from the peels of the bitter orange. This orange is native to Southeast Asia. It is commonly used in foods such as marmalade.
Citrus peels are often made up of mainly limonene. Limonene is a fragrance with a citrus scent. They also contain flavonoids, which have anti-inflammatory properties.
Rose extract comes from various species of the Rosa genus. It has skin conditioning and antioxidant properties due to its polyphenol, flavonoid, and phenolic acid content.
Rosa damascena, Rosa centifolia, and Rosa gallica.
Just keep in mind that rose extracts contain known fragrance allergens like citronellol, geraniol, linalool, and limonene.
Learn more about Rose ExtractAlthaea Officinalis Root Extract is from a plant called the Marsh Mallow plant. This plant is indigenous to Europe, West Asia, and North Africa.
Marsh Mallow root is an emollient and antioxidant. It helps sooth and soften the skin. When applied to the skin, it blocks enzymes that break down hyaluronic acid.
The marshmallow we eat today is based on an ancient Egyptian dessert made from this plant (Marshmallows do not contain this plant anymore).
Learn more about Althaea Officinalis Root ExtractThis ingredient is also known as Slippery Elm Bark Extract.
This ingredient comes from the leaves of the comfrey plant and has skin conditioning properties.
Comfrey produces a wonderful compound that you might have heard of already: allantoin.
Allantoin is well-studied for promoting the skin's natural repair process and helping skin look smoother. Comfrey is also rich in antioxidants like Rosmarinic acid and Caffeic Acid.
Research has shown that these compounds work together to help calm redness, protect against oxidative stress, and support overall skin health.
Learn more about Symphytum Officinale Leaf ExtractParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumBenzyl Alcohol is an aromatic alcohol with several roles: it's a preservative, solvent, and mild fragrance component with a floral scent.
This ingredient has been deemed safe for use in cosmetic formulations at concentrations up to 5%, and up to 10% in hair dyes. You'll typically see 0.5-2% in most rinse-off or leave-on products.
As a preservative, it works by disrupting the membrane of microbial proteins. This helps keep bacteria and fungi from growing in your products.
The sensitization picture is actually quite assuring as well:of nearly 71,000 patients patch tested with benzyl alcohol, only 0.21% showed a positive reaction with most of them being weakly positive.
This led researchers to conclude that benzyl alcohol cannot be regarded as a significant contact allergen.
It is worth noting this ingredient is classified as one of the EU's regulated fragrance allergens and restricted to 1% in finished products.
Labels must also declare it in concentrations above 0.001% in leave-on products and 0.01% in rinse-off products.
At concentrations around 5%, localized redness and itching can appear as a direct irritant response and not as a true allergic reaction.
Learn more about Benzyl AlcoholXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumCellulose Gum is a water-soluble polymer that comes from cellulose. It is used to change the texture of a product and to help stabilize emulsions.
As an emulsifier, cellulose gum specifically thicken the texture of water-based products.
This ingredient is considered hypoallergenic and non-toxic. Cellulose Gum can be found in cosmetics, food, and other household goods such as paper products.
Learn more about Cellulose GumGlyceryl Laurate isn't fungal acne safe.
Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidReviews
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Where it's from
VeraLab is a Italian brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated May 8, 2025 • Added by ktmgiu