Madeca21 Relief Spot Care Patch
A facial treatment with 19 ingredients, including BHA, exfoliants, and hyaluronic acid.
Overview
What it is
Facial treatment with 19 ingredients that contains BHA, exfoliants and hyaluronic acid
Cool Features
It is reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores and better texture
Free From
It doesn't contain any parabens, silicones or sulfates
Fun facts
Madeca21 is from South Korea. This product is used in 2 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Acrylates Copolymer
Vinyl Caprolactam/Vp/Dimethylaminoethyl Methacrylate Copolymer
Skin ConditioningEpilobium Angustifolium Flower/Leaf/Stem Extract
Skin ConditioningButylene Glycol
HumectantMelaleuca Alternifolia Leaf Oil
AntioxidantPvp
Emulsion StabilisingSalicylic Acid
MaskingPhenoxyethanol
PreservativePolysorbate 80
EmulsifyingVitis Vinifera Seed Extract
AntimicrobialSodium Metabisulfite
AntioxidantVolcanic Ash
AbrasivePhytosphingosine
Skin ConditioningSodium Hyaluronate
HumectantLimonene
PerfumingLinalool
PerfumingWater
Skin ConditioningAlcohol Denat.
AntimicrobialAlcohol
AntimicrobialAcrylates Copolymer, Vinyl Caprolactam/Vp/Dimethylaminoethyl Methacrylate Copolymer, Epilobium Angustifolium Flower/Leaf/Stem Extract, Butylene Glycol, Melaleuca Alternifolia Leaf Oil, Pvp, Salicylic Acid, Phenoxyethanol, Polysorbate 80, Vitis Vinifera Seed Extract, Sodium Metabisulfite, Volcanic Ash, Phytosphingosine, Sodium Hyaluronate, Limonene, Linalool, Water, Alcohol Denat., Alcohol
Key Ingredients
Benefits
Concerns
Ingredients Explained
Acrylates Copolymer is used as a film-forming agent and texture enhancer.
After applied, Acrylates Copolymer forms a thin film cover that helps skin feel more soft. It can help sunscreens become more water-resistant.
It is also used to make a product more thick.
Learn more about Acrylates CopolymerWe don't have a description for Vinyl Caprolactam/Vp/Dimethylaminoethyl Methacrylate Copolymer yet.
We don't have a description for Epilobium Angustifolium Flower/Leaf/Stem Extract yet.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolThis tea tree oil comes from the leaves of the Tea Tree plant. Tea tree oil has antioxidant, anti-inflammatory, and antimicrobial properties.
According to the book Journal of Profiles of Drug Substances, tea tree helps in reducing acne-causing bacteria such as Propionibacterium acnes. This is due to the Terpinen components of tea tree oil.
Tea tree may cause sensitivity and irritation for some people. This oil naturally contains fragrance such as linalool and limonene.
However, research shows irritation usually occurs when using pure tea tree oil and not in cosmetic products.
Tea tree oil was found to help relieve the symptoms of psoriasis in one study.
Tea tree oil is toxic when ingested. Another study showed it to caused damage to the nervous system of dogs and cats when applied to their skin or given orally.
Learn more about Melaleuca Alternifolia Leaf OilPvp is a water-soluble synthetic polymer and common hairstyling ingredient. It is a film-forming ingredient and used to "hold" specific shapes of hair.
In cosmetics, PVP helps products like sunscreens and color cosmetics last longer and wear more evenly.
It is less effective in high-humidity. It tends to draw moisture, but this moisture dismantles the structure and "hold".
PVP is generally well tolerated on skin and toxicity studies are negative for dermal irritation.
Learn more about PvpSalicylic Acid (also known as beta hydroxy acid or BHA) is a well-known ingredient for treating skin that struggles with acne and clogged pores. It exfoliates both the skin's surface and deep within the pores to help clear out buildup, control oil, and reduce inflammation.
Unlike AHAs (alpha hydroxy acids), salicylic acid is oil-soluble. This allows it to penetrate into pores which makes it especially effective for treating blackheads and preventing future breakouts.
Salicylic acid is also known for its soothing properties. It has a similar structure to aspirin and can calm inflamed or irritated skin, making it a good option for acne-prone skin that is also sensitive.
Concentrations of 0.5-2% are recognized by the U.S. FDA as an over-the-counter topical acne product.
It can cause irritation and/or dryness if one's skin already has a compromised moisture barrier, so it's best to focus on repairing that before introducing this ingredient into your routine.
While salicylic acid does not increase sun sensitivity, it’s still important to wear sunscreen daily to protect your skin.
If you are looking for the ingredient called BHA or Butylated Hydroxyanisole, click here.
Learn more about Salicylic AcidPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Polysorbate 80 is a surfactant and emulsifier. It is used to keep ingredients together, and prevent oils and waters from separating.
It is made from polyethoxylated sorbitan and oleic acid. This ingredient can be found in cosmetics, foods, and medicine. It is water-soluble.
Polysorbate 80 may not be fungal acne safe.
Learn more about Polysorbate 80Vitis Vinifera Seed Extract comes from the grape vine. Grape seeds are a byproduct of creating grape juice or wine.
The components of grape seeds have many skin benefits. Research has found it to be antimicrobial and anti-inflammatory. It also contains many potent antioxidants such as Vitamin E , Vitamin C, proanthocyanidins, polyphenols, flavonoids, and anthocyanins. Proanthocyanidin has been shown to help even out skin tone.
Antioxidants help fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. Antioxidants help stabilize free-radicals by donating extra electrons. Grape seed extract may help reduce the signs of aging.
The antimicrobial properties of grape seed may help treat acne. However, more research is needed to support this claim.
Grape seed has also been found to help absorb UV rays. Grape seed extract should not replace your sunscreen.
Learn more about Vitis Vinifera Seed ExtractSodium metabisulfite is also known as Sodium Pyrosulfite. It is a preservative, antioxidant, and disinfectant.
As a preservative, it helps stabilize cosmetic formulas without affecting their color or scent.
Volcanic Ash is an exfoliant.
Phytosphingosine is a phospholipid naturally found in our skin as a building block for ceramides.. It helps moisturize, soothe, and protect skin.
Phytosphingosine contributes to your skin's natural moisturizing factor (NMF). The NMF is responsible for hydration, a strong barrier, and plasticity. Our NMF decreases with age. Increasing NMF leads to more healthy and hydrated skin.
Studies show products formulated with NMF ingredients help strengthen our skin's barrier. Having a healthy skin barrier reduces irritation and increases hydration. Our skin barrier is responsible for having plump and firm skin. It also helps protect our skin against infection, allergies, and inflammation.
Fun fact: Phytosphingosine is abundant in plants and fungi.
More ingredients that help boost collagen in skin:
Learn more about PhytosphingosineSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateLimonene is a fragrance that adds scent and taste to a formulation.
It's found in the peel oil of citrus fruits and other plants such as lavender and eucalyptus. The scent of limonene is generally described as "sweet citrus".
Limonene acts as an antioxidant, meaning it helps neutralize free radicals.
When exposed to air, oxidized limonene may sensitize the skin. Because of this, limonene is often avoided by people with sensitive skin.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.
Learn more about LimoneneLinalool is a fragrance and helps add scent to products. It's derived from common plants such as cinnamon, mint, citrus, and lavender.
Like Limonene, this ingredient oxidizes when exposed to air. Oxidized linalool can cause allergies and skin sensitivity.
This ingredient has a scent that is floral, spicy tropical, and citrus-like.
Learn more about LinaloolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterAlcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.
The "denat" part just means "denatured"; common denaturants include Denatonium Benzoate, t-butyl alcohol, and Diethyl Phthalate. This step makes the alcohol undrinkable (and lets brand skip taxes related to beverage alcohol).
This ingredient gets a bad rep because it is irritating and drying due to its astringent property. Astringents draw out natural oils in tissue to constrict pores and dry out your skin.
However, alcohol denat. is not all that bad.
Due to its low molecular weight, alcohol denat. tends to evaporate quickly. One study on pig skin found half of applied alcohol evaporated in 10 seconds and less than 3% stayed on skin.
This also helps other ingredients become better absorbed upon application.
Studies are conflicted about whether this ingredient causes skin dehydration. One study from 2005 found adding emollients to propanol-based sanitizer decreased skin dryness and irritation. Another study found irritation only occurs if your skin is already damaged.
Small amounts of alcohol are generally tolerated by oily skin or people who live in humid environments.
The rule of thumb is this ingredient will probably not affect your skin much if it is near the end of an ingredients list.
One thing to note:
People with ALDH2 (aldehyde dehydrogenase 2) deficiency may experience skin irritation from continued alcohol use. About 8% of the world's population have this deficiency.
The Cosmetic Ingredient Review Expert Panel has determined denatured alcohols to be safe for use in concentrations between 0.05% and 12% (depending on which denaturant is used).
Also...
This ingredient has antimicrobial and solvent properties.
The antimicrobial property helps preserve products and increase their shelf life. As a solvent, it helps dissolve other ingredients.
Look for formulas that contain glycerin, hyaluronic acid, or panthenol if you want to offset any drying effect.
This ingredient will trip away your skin's natural oils/lipids that help it lock in moisture. This can worsen dryness, trigger eczema flare-ups, and aggravate rosacea.
Be sure to patch test any product with this ingredient if you have dry or sensitive skin, eczema, or rosacea.
Learn more about Alcohol Denat.This ingredient is also called ethanol or ethyl alcohol. It is denatured, meaning made undrinkable for cosmetic use.
In formulas, it:
Is it bad for your skin?
The answer comes down to concentration. Patch and wash studies have found highly concentrated alcohol-based hand rubs (60-100%) cause less barrier disruption than washing with a basic detergent like SLS. The only measurable effect in these studies was a temporary dip in skin hydration.
Concentrations below 12-15% in leave-on cosmetics is generally well-tolerated. Concentrations above start to see increased transepidermal water loss (TEWL) and reduced hydration.
In concentrations about 58%, it creates temporary channels in your skin's lipid layers to become more permeable and allow other ingredients to slip through easily.
This ingredient can be up to 80% of the formula in alcohol-based perfumes.
Overall, this ingredient is probably harmless if found lower down an ingredients list but worth side-eyeing if it's high up (especially if your barrier is already struggling).
Alcohol can worsen dry skin, eczema, and oily skin, especially at higher concentrations. This is because it can increase transepidermal water loss and decrease hydration to disrupt the skin barrier.
According to the National Rosacea Society based in the US, you should be mindful of products with these alcohols in the top half of ingredients.
True allergic contact dermatitis to ethanol is uncommon, but be sure to patch test if you have dry or sensitive skin.
Learn more about AlcoholReviews
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Where it's from
Madeca21 is a Korean brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated May 14, 2026 • Added by mugi