3INA The Sorbet Face Cream

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Besides holding formulas together, it also leaves a silky and lightweight feel on skin without the greasiness. A manufacturer also claims it can help with the controlled release of active ingredients.

The CIR Expert Panel found this ingredient to not be sensitizing in concentrations up to 15% in human maximazation testing and dimethicone-based compounds were not comedogenic.

It has a high molecular weight well above 1,000 g/mol which means it limits meaningful skin penetration.

A 2019 study specifically tested this ingredient and found no observable Malassezia growth in its presence.

You might see people debate whether Sodium Chloride is comedogenic, but there actually haven't been any comedogenic tests done on it. Either way, the overall formulation of a product matters a lot more than any single ingredient.

You might see this ingredient used in scrubs as a primary exfoliating ingredient.

Research highlights its role in antioxidant activity, anti-inflammatory effects, skin barrier protection, and wound healing support.

In vivo research has shown that transepidermal water loss (TEWL) caused by irritant exposure can be reverse with squalene supplementation (pointing to barrier recovery support).

Its antioxidant activity is backed by ex vivo and cell-based evidence showing it can scavenge free radicals but large-scale human clinical trials isolating this effect remain limited.

One study found squalene regulated proinflammatory behavior in ways relevant to wound healing, and in vitro fibroblast studies also shows it stimulates cell migration which is a key step in skin repair.

There's just one nuance to know about this ingredient:

Squalene is particularly vulnerable to oxidation; it breaks down from UV exposure 10x faster than the other lipids on your skin's surface. The byproducts of that breakdown can clog pores and trigger inflammation, potentially worsening acne.

This is why squalene is often hydrogenated into its stable counterpart: squalane (with an "a"). Most great formulations will have alreadu kept this in mind.

Squalene has shown no significant clinical evidence of sensitization and is a great hydrating ingredient.

Hectorite is a rare, white clay mineral.

As an emollient, it softens and hydrates skin by forming a thin barrier that locks in moisture.

Clinical studies have found it to be non-irritating and non-sensitizing. The CIR Expert Panel has evaluated the available safety data and concluded it is safe for topical use.

Because of the oleic acid content, this ingredient may not be fungal acne safe.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Two clinical studies in postmenopausal women found that applying argan oil for 60 days significantly improved skin elasticity and moisturization (reduced transepidermal water loss and increased epidermal water content).

Since it is high in oleic and linoleic acid, this ingredient may not be fungal acne safe. Both of these fall in the C11-C24 range that Malassezia yeast can metabolize.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

This dye is commonly found in makeup because it imparts a vivid color. Some types of this dye change color based on pH level and interaction with moisture:

Your skin has a natural pH of around 4.5 - 5.5.

According to the FDA, CI 45410 is not permitted for use in eye products.

Red 27 is a flourescein dye and commonly used as a fluorescent tracer in medicine.

Some people may experience allergies from this dye, especially asthmatics and those with an aspirin intolerance.