Paula's Choice Regular Strength Daily Skin Clearing Treatment with 2.5% Benzoyl Peroxide Versus Clinique Moisture Surge 72-Hour Auto-Replenishing Hydrator
This acne treatment is formulated around Benzoyl Peroxide and Bisabolol to clear breakouts and calm redness.
This barrier-repair moisturizer is formulated around Sodium Hyaluronate to strengthen the skin barrier and hydrate skin.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningPropylene Glycol
HumectantBenzoyl Peroxide
Bisabolol
AntioxidantAllantoin
Skin ConditioningAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingHydroxyethylcellulose
Emulsion StabilisingSodium Citrate
BufferingLaureth-4
EmulsifyingCaprylyl Glycol
EmollientSodium Hydroxide
BufferingDisodium EDTA
ChelatingHexylene Glycol
EmulsifyingPhenoxyethanol
PreservativeWater
Skin ConditioningDimethicone
EmollientButylene Glycol
HumectantGlycerin
HumectantTrisiloxane
Skin ConditioningTrehalose
HumectantSucrose
HumectantAmmonium Acryloyldimethyltaurate/Vp Copolymer
Hydroxyethyl Urea
HumectantCamellia Sinensis Leaf Extract
AntimicrobialSilybum Marianum Extract
Skin ConditioningBetula Alba Bark Extract
MaskingSaccharomyces Lysate Extract
HumectantAloe Barbadensis Leaf Water
MaskingThermus Thermophillus Ferment
Skin ConditioningCaffeine
Skin ConditioningSorbitol
HumectantPalmitoyl Hexapeptide-12
Skin ConditioningSodium Hyaluronate
HumectantCaprylyl Glycol
EmollientOleth-10
EmulsifyingSodium Polyaspartate
HumectantSaccharide Isomerate
HumectantHydrogenated Lecithin
EmulsifyingTocopheryl Acetate
AntioxidantAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingGlyceryl Polymethacrylate
Tromethamine
BufferingPEG-8
HumectantHexylene Glycol
EmulsifyingMagnesium Ascorbyl Phosphate
AntioxidantDisodium EDTA
ChelatingBHT
AntioxidantPhenoxyethanol
PreservativeCI 14700
Cosmetic ColorantCI 19140
Cosmetic ColorantWater, Dimethicone, Butylene Glycol, Glycerin, Trisiloxane, Trehalose, Sucrose, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Hydroxyethyl Urea, Camellia Sinensis Leaf Extract, Silybum Marianum Extract, Betula Alba Bark Extract, Saccharomyces Lysate Extract, Aloe Barbadensis Leaf Water, Thermus Thermophillus Ferment, Caffeine, Sorbitol, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Caprylyl Glycol, Oleth-10, Sodium Polyaspartate, Saccharide Isomerate, Hydrogenated Lecithin, Tocopheryl Acetate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Glyceryl Polymethacrylate, Tromethamine, PEG-8, Hexylene Glycol, Magnesium Ascorbyl Phosphate, Disodium EDTA, BHT, Phenoxyethanol, CI 14700, CI 19140
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
Learn more about Acrylates/C10-30 Alkyl Acrylate CrosspolymerCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAHexylene Glycol is a multitasker ingredient that works as a solvent, humectant, emulsifier, viscosity reducer, and preservative booster.
It is able to dissolve both water and oil-soluble ingredients to stabilize tricky actives and make products spread more easily.
As a humectant, it pulls water into the skin. But it's a pretty minor moisturizing ingredient compared to other humectants, like glycerin.
Interestingly, it can act as a mild penetration enhancer. One in vitro study on human skin found a 12% concentration upped the absorption of mometasone furoate (a medicinal ingredient used to treat inflammatory skin conditions) up to 7%.
This ingredient is typically used at levels of 0.1-10% depending on the role it's playing.
A patch test study on eczema patients didn't find a significant increase in irritation versus the control group, but the potential for irritation rises at higher concentrations.
Learn more about Hexylene GlycolPhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water