BioNike Aknet Azerose Intensive Care Versus Paula's Choice Clinical Niacinamide 20% Treatment
Updated on February 11, 2025
Overview
What they are
These products are both cruelty-free and reef safe facial treatments. They have a total of 10 ingredients in common
Cool Features
They both contain exfoliants and niacinamide
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, common allergens, parabens, silicones or sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
BioNike Aknet Azerose Intensive Care 25 ingredients
Paula's Choice Clinical Niacinamide 20% Treatment 25 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
BioNike Aknet Azerose Intensive Care 25 ingredients
Paula's Choice Clinical Niacinamide 20% Treatment 25 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycolic Acid
Buffering
Dipotassium Azelate
Niacinamide
Smoothing
Butylene Glycol
Humectant
Pentylene Glycol
Skin ConditioningMyrtus Communis Leaf Water
MaskingMagnesium Aluminum Silicate
AbsorbentCanola Oil
Emollient
Succinic Acid
BufferingSodium Hydroxide
Buffering4-T-Butylcyclohexanol
Masking
Xanthan Gum
EmulsifyingTocopheryl Acetate
Antioxidant
Aminobutyric Acid
Sclerotium Gum
Emulsion StabilisingLecithin
Emollient
Pullulan
Caprylyl Glycol
EmollientPotassium Cetyl Phosphate
EmulsifyingSilica
Abrasive
Lactic Acid
Buffering
Propanediol
Solvent
Citric Acid
Buffering
Trisodium Ethylenediamine Disuccinate
Water, Glycolic Acid, Dipotassium Azelate, Niacinamide, Butylene Glycol, Pentylene Glycol, Myrtus Communis Leaf Water, Magnesium Aluminum Silicate, Canola Oil, Succinic Acid, Sodium Hydroxide, 4-T-Butylcyclohexanol, Xanthan Gum, Tocopheryl Acetate, Aminobutyric Acid, Sclerotium Gum, Lecithin, Pullulan, Caprylyl Glycol, Potassium Cetyl Phosphate, Silica, Lactic Acid, Propanediol, Citric Acid, Trisodium Ethylenediamine Disuccinate
Water
Skin ConditioningNiacinamide
Smoothing
Pentylene Glycol
Skin ConditioningButylene Glycol
Humectant
Glycerin
Humectant
Acetyl Glucosamine
Skin ConditioningAscorbyl Glucoside
Antioxidant
Glycyrrhiza Glabra Root Extract
Bleaching
Spiraea Ulmaria Extract
AstringentPortulaca Oleracea Extract
Skin Conditioning
Camellia Japonica Flower Extract
EmollientEpigallocatechin Gallate
Antioxidant
Boerhavia Diffusa Root Extract
Skin Protecting
Camellia Sinensis Leaf Extract
Antimicrobial
Allantoin
Skin Conditioning
Lecithin
Emollient
Pullulan
Panthenol
Skin Conditioning
Silica
Abrasive
Xanthan Gum
EmulsifyingSclerotium Gum
Emulsion StabilisingPropanediol
Solvent
Sodium Phytate
Phenoxyethanol
Preservative
Ethylhexylglycerin
Skin ConditioningWater, Niacinamide, Pentylene Glycol, Butylene Glycol, Glycerin, Acetyl Glucosamine, Ascorbyl Glucoside, Glycyrrhiza Glabra Root Extract, Spiraea Ulmaria Extract, Portulaca Oleracea Extract, Camellia Japonica Flower Extract, Epigallocatechin Gallate, Boerhavia Diffusa Root Extract, Camellia Sinensis Leaf Extract, Allantoin, Lecithin, Pullulan, Panthenol, Silica, Xanthan Gum, Sclerotium Gum, Propanediol, Sodium Phytate, Phenoxyethanol, Ethylhexylglycerin
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolPentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumSclerotium Gum is a polysaccharide gum made by the fungus, Sclerotium rolfssii. It is similar to xanthan gum.
In cosmetics, Sclerotium Gum is used to thicken the texture and to help stabilize other ingredients.
As an emulsifier, Sclerotium Gum helps prevent ingredients from separating, such as water and oil.
Learn more about Sclerotium GumLecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.
This ingredient has emollient and emulsifying properties.
As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.
As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.
This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.
Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.
We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.
Learn more about LecithinPullulan is a low viscosity polysaccharide (a long chain carbohydrate) with binding and film forming properties when dissolved in water. It is used to create a "silicone-like" or silky feel in cosmetics without adding viscosity.
According to a manufacturer, this ingredient's ability to easily dissolves makes it a great carrier for active ingredients.
Due to it being edible and tasteless, you'll likely find this ingredient in breath freshener strips. This ingredient is produced from the starch of the fungus, Aureobasidium pullulans.
Pullulan is stable over a broad-range of pH.
Learn more about PullulanSilica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.
Silica is often used for absorption and can help reduce shine when products are applied. Silica occurs in naturally in materials like clay and sandstone, and it can also be produced synthetically.
Silica is present naturally within the skin during collagen production and when reducing inflammation.
Learn more about SilicaPropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.Â
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
BioNike Aknet Azerose Intensive Care 25 ingredients
Paula's Choice Clinical Niacinamide 20% Treatment 25 ingredients
Reviews
Here's what our community thinks
BioNike Aknet Azerose Intensive Care 25 ingredients
Paula's Choice Clinical Niacinamide 20% Treatment 25 ingredients
I wanted to find a niacinamide product that had other benefits like antioxidants. This caused huge cystic acne and flared up my FA. I suspect it's due to the lecithin which I found is not FA safe and in higher concentrations is problematic for acne prone skin.
Lecithin is a mixture of diglycerides of stearic, palmitic, and oleic acids. It can contain soybean oil and phospholipid fatty acids Show more
Good product :) My pores shrank and actually made a difference compared to 15 and 10 percent concentrations. I was surprised there was no irritation even after using twice a day. My skin loves niacinamide.
