Explore Routine Login
Versus

Avène Cleanance Comedomed Concentrate Blemish Control Serum Versus Bioderma Sébium Global

General Moisturizer
General Moisturizer
French Brand France
French Brand France

Updated on September 18, 2023

Overview

What they are

These products are both reef safe general moisturizers. They have a total of 4 ingredients in common

Cool Features

They both contain exfoliants

Suited For

They're both likely to be good for dry skin and brightening skin

Free From

They both do not contain any common allergens, oils, parabens or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Cleanance Comedomed Concentrate Blemish Control Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Isopropyl Alcohol Solvent
0 / 0 Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon
AlcoholAlcohol Icon 5 Concerns

Isopropyl Alcohol is more commonly known as rubbing alcohol. It is most commonly used as a solvent, meaning it helps other ingredients dissolve.

0 Com. / 0 Irr.
Very Disliked Full details ->
Peg-6 Humectant, Solvent

We don't have a description for Peg-6.

Unknown Full details ->
Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Silybum Marianum Fruit Extract Skin Conditioning

We don't have a description for Silybum Marianum Fruit Extract.

Unknown Full details ->
Silica Abrasive, Absorbent
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon
ExfoliantExfoliant Icon 2 Concerns

Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.

Disliked Full details ->
Polyacrylate-13

Polyacrylate-13 is a type of acrylate polymer. Acrylate polymers are commonly used as adhesives in cosmetics.

Disliked Full details ->
Polyisobutene

Polyisobutene is a synthetic polymer made from isobutene.

Disliked Full details ->
Polysorbate 20 Emulsifying
0 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

0 Com. / 0 Irr.
Very Disliked Full details ->
Sorbitan Isostearate Emulsifying
1-2 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Sorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.

1-2 Com. / 0 Irr.
Very Disliked Full details ->
Sébium Global
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

C12-13 Alkyl Lactate Emollient, Skin Conditioning

We don't have a description for C12-13 Alkyl Lactate.

Unknown Full details ->
Citric Acid Buffering, Masking
AHA IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation IconMay worsen Rosacea Icon
AHAAHA Icon 4 Benefits 2 Concerns

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

Disliked Full details ->
Dipropylene Glycol Masking, Solvent

Dipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.

Disliked Full details ->
Cyclopentasiloxane Emollient, Skin Conditioning, Solvent
Silicon Icon
SiliconSilicon Icon

Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.

Disliked Full details ->
Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Methyl Methacrylate Crosspolymer

We don't have a description for Methyl Methacrylate Crosspolymer.

Disliked Full details ->
Zinc Gluconate Skin Conditioning

We don't have a description for Zinc Gluconate.

Salicylic Acid Masking, Preservative, Skin Conditioning
BHA IconPreservative IconGood for Oily Skin IconGood for Minimizing Pores IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconCan worsen Dry Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon
BHABHA Icon PreservativePreservative Icon 5 Benefits 4 Concerns

Salicylic Acid (also known as beta hydroxy acid or BHA) is one of the most well-known ingredients for treating skin that struggles with blackheads and acne. It helps to exfoliate both the skin's surface and pores, and also acts as an anti-inflammatory agent.

Arachidyl Alcohol Emollient, Emulsion Stabilising

Arachidyl Alcohol is a fatty alcohol made from peanut oil. It is an emollient, emulsifier, and thickener.

Very Disliked Full details ->
Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0 Silicon Icon
SiliconSilicon Icon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

1 Com. / 0 Irr.
Very Disliked Full details ->
Behenyl Alcohol Emollient, Emulsion Stabilising
Fatty Alcohol Icon
Fatty AlcoholFatty Alcohol Icon

A type of fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product. They are usually derived from natural fats and oils and therefore do not have the same drying or irritating effect as traditional alcohols.

Disliked Full details ->
Glyceryl Stearate Emollient, Emulsifying
1 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Glyceryl Stearate is a mix of glycerin and stearic acid.

1 Com. / 0 Irr.
Disliked Full details ->
Peg-100 Stearate
0 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Peg-100 Stearate is an emollient and emulsifier. PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.

0 Com. / 0 Irr.
Very Disliked Full details ->
Silica Abrasive, Absorbent
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon
ExfoliantExfoliant Icon 2 Concerns

Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.

Disliked Full details ->
Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Arachidyl Glucoside Emulsifying

We don't have a description for Arachidyl Glucoside.

Disliked Full details ->
C30-45 Alkyl Cetearyl Dimethicone Crosspolymer Emollient, Skin Conditioning

We don't have a description for C30-45 Alkyl Cetearyl Dimethicone Crosspolymer.

Unknown Full details ->
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Emulsion Stabilising

This is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.

Disliked Full details ->
Glycyrrhetinic Acid Skin Conditioning

We don't have a description for Glycyrrhetinic Acid.

Squalane Emollient, Skin Conditioning
1 / 0 Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

1 Com. / 0 Irr.
Bakuchiol Antimicrobial, Antioxidant, Emollient
Antioxidant IconHelps with Anti-Aging IconGood for Dark Spots IconHelps brighten skin Icon
AntioxidantAntioxidant Icon 3 Benefits

Bakuchiol is a plant-derived antioxidant (it's vegan!). It is often called the replacement for retinol although it is not part of the same family.

Sodium Metabisulfite Antioxidant, Preservative
Antioxidant IconPreservative Icon
AntioxidantAntioxidant Icon PreservativePreservative Icon

Sodium Metabisulfite is an antioxidant and is a preservative.

Xylitol Humectant, Skin Conditioning

Xylitol is a humectant and prebiotic. It can help with dry skin.

Propylene Glycol Humectant, Skin Conditioning, Solvent
0 / 0 May worsen Eczema Icon
May worsen EczemaMay worsen Eczema Icon

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

0 Com. / 0 Irr.
Disliked Full details ->
Polysorbate 60 Emulsifying
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.

Very Disliked Full details ->
Sorbitan Isostearate Emulsifying
1-2 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Sorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.

1-2 Com. / 0 Irr.
Very Disliked Full details ->
Fructooligosaccharides Humectant, Skin Conditioning

Fructooligosaccharides is an alternative sweetener. It is often derived from the blue agave plant.

Mannitol Humectant, Masking, Moisturising

Mannitol is a sugar alcohol. It is a humectant and moisturizes the skin. In vitro (not tested on a living organism), mannitol displays antioxidant properties.

Propyl Gallate Antioxidant, Perfuming
Antioxidant IconFragrance Icon
AntioxidantAntioxidant Icon FragranceFragrance Icon

Propyl Gallate is an antioxidant and is a fragrance.

Caprylic/Capric Triglyceride Masking, Skin Conditioning

Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

Ginkgo Biloba Leaf Extract Skin Conditioning

Ginkgo Biloba Leaf Extract comes from the leaves of the Ginkgo tree. This tree is native to China and has been used in traditional Chinese medicine for thousands of years.

Rhamnose Humectant, Masking

We don't have a description for Rhamnose.

Laminaria Ochroleuca Extract Skin Conditioning
Helps reduce irritation Icon
Helps reduce irritationHelps reduce irritation Icon

Laminaria Ochroleuca Extract is a type of kelp. It helps sooth and hydrate the skin. By nourishing the skin's barrier, it may also help relieve irritation.

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Abrasive, Absorbent
Disliked

Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.

Silica is often used for absorption and can help reduce shine when products are applied. Silica occurs in naturally in materials like clay and sandstone, and it can also be produced synthetically.

Silica is present naturally within the skin during collagen production and when reducing inflammation.

Learn more about Silica
Emulsifying
Very Disliked

Sorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.

As an emulsifier, Sorbitan Isostearate prevents oils and water from separating.

Due to its isostearic acid base, it may not be safe for Malassezia or fungal acne.

Learn more about Sorbitan Isostearate

Ingredient Ratings

Here's what our community thinks of the ingredients in these products.

Cleanance Comedomed Concentrate Blemish Control Serum
2
6
2
liked
mixed
disliked
not rated
Sébium Global
13
4
16
2
liked
mixed
disliked
not rated

When to use

21 Routines
48% use in am
52% use in pm
81% use every day
28 Routines
46% use in am
54% use in pm
86% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Avène Cleanance Comedomed Concentrate Blemish Control Serum 10 ingredients

5.0 /5
from 1 rating
Great Value (1) Light Scent (1) Sticky (1)
pamsipam's avatar

Plamena Mihaylova

28 days ago · Oily Skin
Review

Been using it for 2 years and it’s the only thing keeping my pores clean

Bioderma Sébium Global 35 ingredients

1.0 /5
from 1 rating
Broke Me Out (1) Drying (1) Irritating (1)
AllyF.'s avatar

AllyF.

4 months ago · Combination Skin
Review

Bought this a while back and still can't bring myself to use it to completion. This was far too harsh for my skin and caused a lot of redness, dry...

Bought this a while back and still can't bring myself to use it to completion. This was far too harsh for my skin and caused a lot of redness, dry patches, irritation, and sensitivity.