COLLISTAR Milano Retinol + Panthenol Serum
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COLLISTAR Milano Retinol + Panthenol Serum

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Overview

What it is

Serum with 23 ingredients that contains retinoid and Vitamin E

Cool Features

It is cruelty-free and reef safe

Suited For

It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates

Fun facts

COLLISTAR Milano is from . This product is used in 2 routines created by our community.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

What's inside (and what isn't)

Key Ingredients

Benefits

Ingredients Explained

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Solvent

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. 

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Masking, Skin Conditioning

This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride
Emollient, Skin Conditioning

We don't have a description for Cetearyl Isononanoate yet.

Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.

This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.

Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.

Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.

Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.

Learn more about Pentylene Glycol
Solvent

C15-19 alkane is a mixture of alkanes. Alkanes are hydrocarbons with carbon atoms held together by single bonds.

It is a synthetically created solvent and emollient often used to replace silicones or mineral oil. As an emollient, C15-19 Alkane helps soften and soothe the skin. Emollients create a barrier to trap moisture inside.

C15-19 Alkane is often used with mineral UV filters such as titanium dioxidide and zinc oxide. It helps these UV filter ingredients be more spreadable.

C15-19 Alkane is biodegradable.

Learn more about C15-19 Alkane
Skin Conditioning

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Learn more about Panthenol
Antioxidant, Skin Conditioning

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate

Polyglyceryl-4 Stearate isn't fungal acne safe.

Skin Conditioning

This ingredient is a retinoid. It usually goes by a more common name: "Granactive".

Hydroxypinacolone Retinoate (HPR) belongs to the class of retinoids that also includes retinol and tretinoin.

Retinoids have been proven to:

So what is the difference between all the retinoids?
Most retinoids need to go through a conversion line to become effective on skin. The ending product is retinoic acid. Retinoic acid is AKA tretinoin.

HPR is an ester of tretinoin. Emerging studies suggest HPR to have an added benefit that other retinoids don't have: Low irritation.

A study from 2021 found HPR to have the greatest stability when exposed to light and temperature out of all the commercial retinoids.

A note about naming:
The name "Granactive" is the trade name and the name most commonly used on packages.

Granactive is the name of the mixture - about 90% solvent and 10% HPR. A product with 5% granactive has 0.5% HPR.

Learn more about Hydroxypinacolone Retinoate
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 

Potassium Cetyl Phosphate is the potassium salt of a mixture. This mixture consists of the esters from phosphoricacid and cetyl alcohol.

Potassium Cetyl Phosphate is an emulsifier and cleansing agent. Emulsifiers help stabilize a product. It does this by preventing certain ingredients from separating.

As a cleansing agent, Potassium Cetyl Phosphate helps gather oils, dirts, and pollutants from your skin. This makes it easier to rinse them away with water.

Learn more about Potassium Cetyl Phosphate

Dimethyl Isosorbide is a solvent and helps deliver actives into your skin. It is created from sorbitol.

As a solvent, dimethyl isosorbide helps dissolve other ingredients. This helps ensure even distribution of an ingredient. It may also be used to decrease the thickness of a product.

Studies show dimethyl isosorbide is able to penetrate skin to deliver other ingredients into the skin, making them more effective.

Learn more about Dimethyl Isosorbide
Cleansing, Emulsifying, Skin Conditioning

Sodium Stearoyl Glutamate is an emulsifier and helps condition the skin. It is amino acid-based.

In higher amounts, it may act as a cleansing agent.

Antioxidant

Hydroxyacetophenone is antioxidant with skin conditioning and soothing properties. It also boosts the efficiency of preservatives.

This ingredient is not irritating or sensitizing.

Emulsion Stabilising, Gel Forming

Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Emulsion Stabilising

Polyacrylate Crosspolymer-6 is a texture enhancer and pH adjuster.

It is be used to thicken water-based products and create a gel-texture with a velvet feel.

One manufacturer claims this ingredient to have a pH range of 2-8 and to be biodegradable.

Learn more about Polyacrylate Crosspolymer-6
Skin Conditioning

This ingredient comes from a fatty acid (lauric acid) and amino acid (lysine). It is used to add a silky feel to cosmetics.

According to a manufacturer, its fatty acid base leaves a silky feeling on the skin. It also has emollient properties because of this. Emollients help soften skin by preventing water from evaporating.

Lauroyl lysine is barely soluble in water.

Learn more about Lauroyl Lysine

Caprylhydroxamic Acid is a chelating agent.

Chelating agents help prevent metal ions from binding to other ingredients. This helps prevent unwanted reactions and effects from using the product.

Caprylhydroxamic Acid is often used with natural antimicrobial products as an alternative to preservatives.

Learn more about Caprylhydroxamic Acid
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Learn more about Sodium Hydroxide

Tetrasodium Glutamate Diacetate is a chelating agent. Chelating agents help prevent metal ions from binding to other ingredients. This helps prevent unwanted effects and reactions from a product. These metal ions may come from water and are found in miniscule amounts.

Tetrasodium Glutamate Diacetate can also help other preservatives be more effective.

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Where it's from

COLLISTAR Milano is a Italian brand

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· Published June 16, 2025 Added by usersuper