Advanced Clinicals Brightening Vitamin C Cleanser
A face cleanser with 29 ingredients, including vitamin C and vitamin E.
Overview
What it is
Face cleanser with 29 ingredients that contains Vitamin C and Vitamin E
Cool Features
It is cruelty-free and reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, parabens, silicones or sulfates
Fun facts
Advanced Clinicals is from United States. This product is used in 2 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin ConditioningCocamidopropyl Betaine
CleansingSodium C14-16 Olefin Sulfonate
CleansingAloe Barbadensis Leaf Juice Powder
Skin ConditioningAscorbic Acid
AntioxidantDecyl Glucoside
CleansingSorbitan Laurate
EmulsifyingCocamide Mipa
EmulsifyingCoco-Glucoside
CleansingCitrus Limon Peel Oil
MaskingCitrus Paradisi Peel Oil
MaskingFerulic Acid
AntimicrobialPanax Ginseng Root Extract
EmollientCamellia Sinensis Leaf Extract
AntimicrobialPolysorbate 20
EmulsifyingSodium Chloride
MaskingHydroxyacetophenone
AntioxidantPolyquaternium-10
Caprylyl Glycol
Emollient1,2-Hexanediol
Skin ConditioningGlyceryl Oleate
EmollientSorbeth-230 Tetraoleate
EmulsifyingTetrasodium Glutamate Diacetate
Citric Acid
BufferingSodium Hydroxide
BufferingTocopherol
AntioxidantHydrogenated Vegetable Glycerides Citrate
EmollientPhenoxyethanol
PreservativeLimonene
PerfumingWater, Cocamidopropyl Betaine, Sodium C14-16 Olefin Sulfonate, Aloe Barbadensis Leaf Juice Powder, Ascorbic Acid, Decyl Glucoside, Sorbitan Laurate, Cocamide Mipa, Coco-Glucoside, Citrus Limon Peel Oil, Citrus Paradisi Peel Oil, Ferulic Acid, Panax Ginseng Root Extract, Camellia Sinensis Leaf Extract, Polysorbate 20, Sodium Chloride, Hydroxyacetophenone, Polyquaternium-10, Caprylyl Glycol, 1,2-Hexanediol, Glyceryl Oleate, Sorbeth-230 Tetraoleate, Tetrasodium Glutamate Diacetate, Citric Acid, Sodium Hydroxide, Tocopherol, Hydrogenated Vegetable Glycerides Citrate, Phenoxyethanol, Limonene
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterCocamidopropyl Betaine is a fatty acid created by mixing similar compounds in coconut oil and dimethylaminopropylamine, a compound with two amino groups.
This ingredient is a surfactant and cleanser. It helps gather the dirt, pollutants, and other impurities in your skin to be washed away. It also helps thicken a product and make the texture more creamy.
Being created from coconut oil means Cocamidopropyl Betaine is hydrating for the skin.
While Cocamidopropyl Betaine was believed to be an allergen, a study from 2012 disproved this. It found two compounds in unpure Cocamidopropyl Betaine to be the irritants: aminoamide and 3-dimethylaminopropylamine. High-grade and pure Cocamidopropyl Betaine did not induce allergic reactions during this study.
Learn more about Cocamidopropyl BetaineSodium C14-16 Olefin Sulfonate is a surfactant that helps water and oil mix so that dirt, sweat, sebum, and sunscreen can rinse away easily. It's not technically a sulfate, but behaves similarly in formulas.
What it does:
Sodium C14-16 Olefin Sulfonate is a strong cleansing surfactant and is much stronger than many mild cleansers. Because it works deeply, it can disrupt the skin's barrier. This can lead to dryness or irritation for those with sensitive skin.
Compared to gentler surfactants, it's effective but more likely to dry or irritate if not balanced with soothing ingredients.
CIR considers sodium α-olefin sulfonates (including C14-16) to be safe for use in rinse-off products when properly formulated. It is poorly absorbed through normal skin but absorption increases if the skin barrier is already damaged.
Learn more about Sodium C14-16 Olefin SulfonateAloe Barbadensis Leaf Juice Powder comes from the aloe plant.
You may know Aloe to be a good sunburn reliever and inflammation reducer. This is because it contains many components that are known to help reduce irritation and itchiness.
Aloe leaves are also great moisturizers. They are naturally rich in polysaccharides, a carbohydrate made of sugars. Polysaccharides are able to mimic the carbs found in the top layer of your skin. This can help keep your skin hydrated.
Aloe contains the antioxidants Vitamins A, C, and E. These vitamins neutralize free radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
Aloe does not protect against UV rays, despite it soothing sunburns.
Learn more about Aloe Barbadensis Leaf Juice PowderAscorbic Acid is is pure Vitamin C and is the biologically active form used directly by skin.
Not only is vitamin C great for your overall health and immune system, but it also has plenty of benefits for your skin. It is best supported by academic literature for:
Topical vitamin C has been shown to help neutralize oxidative stress from UV and pollution, helping to improve photoaging and hyperpigmentation when used consistently.
One clinical study found that using 5% topical vitamin C for six months improved signs of photodamaged skin, both on the surface and in the deeper structural layers of the skin.
While vitamin C doesn’t replace sunscreen, studies show it can boost photoprotection when combined with Vitamin E and ferulic acid. These two ingredients help improve stability and protective effects.
The big downside of this ingredient is formulation difficulty. Vitamin C is prone to oxidation and doesn't penetrate the skin unless formulated correctly. Research found that vitamin C absorbs into the skin best at a low pH (< 3.5) with about 20% being the upper limit for effective absorption.
Skin levels can saturate after repeated application; this means your skin won’t keep absorbing more once it’s full of vitamin C. This is why more isn’t always better with vitamin C and why very high concentrations don’t necessarily give extra benefits.
Ascorbic acid generally works well with many skincare ingredients but can be irritating when combined with other active ingredients. Strong oxidizing acne treatments like benzoyl peroxide can reduce the effectiveness of vitamin C if they are used at the same time; they are often recommended for use at different times of day.
Read more about other types of Vitamin C:
Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.
Learn more about Ascorbic AcidDecyl Glucoside is a plant-derived surfactant and emulsion stabilizer. It is created by reacting glucose with the fatty acids from plants.
Like all surfactants, it works by lowering the surface tension between water and oil. This makes it so that dirt, sebum, and makeup can be lifted off your skin and rinsed away. It also produces a dense and creamy foam.
Because it has a neutral charge, it is compatible with a wide range of ingredients and stays stable across a broad pH range/water hardiness conditions.
Patch testing has shown it to have the lowest irritation potential among common cleansing surfactants (like SLS).
Typical use levels range from 5-20% in rinse-off cleansers.
One thing worth knowing: The American Contact Dermatitis Society named the parent family, alkyl glucosides, "Allergen of the Year" in 2017. The prevalence of allergy is pretty low but be sure to patch test if you've reacted to "gentle" or sulfate-free cleansers before.
This ingredient is fungal acne safe because the fatty alcohol portion of this ingredient is below the C11-24 chain length that Malassezia can metabolize.
Learn more about Decyl GlucosideSorbitan Laurate is created from lauric acid and derivatives from sorbitol. It is an emulsifier.
We don't have a description for Cocamide Mipa yet.
Coco-Glucoside is a surfactant, or a cleansing ingredient. It is made from glucose and coconut oil.
Surfactants help gather dirt, oil, and other pollutants from your skin to be rinsed away.
This ingredient is considered gentle and non-comedogenic. However, it may still be irritating for some.
Learn more about Coco-GlucosideCitrus Limon Peel Oil is created from the peels of the lemon. It is used to add a lemon-scent to products. Lemon peel oil also has antibacterial, antifungal, and antioxidant properties. However, it may also cause phototoxicity and sensitize skin.
Lemon peel oil contains limonene, a skin sensitizing ingredient. Another component is furanocoumarin, which induces phototoxicity in skin.
Furanocoumarins bind and destabilize your DNA to increase the rate of sunburn.
Most reputable companies will remove furanocoumarins from their formulations.
Learn more about Citrus Limon Peel OilThis ingredient is also known as grapefruit peel oil. It is mainly used as a fragrance/perfuming ingredient and is made up of about 99-92% limonene.
Though in vitro or food science has shown this oil to be antibacterial, possess antioxidant activity, and be anti-inflammatory, there's very little research testing it directly on human skin or in cosmetics.
Limonene is a known skin sensitizer. Because grapefruit peel oil can contain furanocoumarins, this ingredient can also cause phototoxicity. It is possible to created furanocoumarin-free versions that are not phototoxic; it is best to reach out to the brand if you have questions about this ingredient in your cosmetics.
Learn more about Citrus Paradisi Peel OilFerulic Acid is a plant based antioxidant that can be naturally found in the cell walls of grains like rice, oats, and corn. It has antioxidant and antimicrobial properties, and has the ability to boost the performance of other antioxidants as well.
A well-known study found that adding Ferulic Acid to a solution of Vitamins C and E doubled the photoprotection of skin. This is why you'll often see it paired with Vitamin C or Vitamin E serums rather than sold on its own.
A 2025 review of 18 human studies found that using Ferulic Acid (0.5-1%) daily for one to three months showed improvements in:
As far as allergies go, Ferulic acid is generally well-tolerated but can cause an allergic reaction in very rare cases. It's also worth noting that Ferulic acid is often extracted from plant sources like rice bran or wheat bran, so be sure to path test if you have known grain allergies.
Outside of skincare, researchers are also looking into Ferulic Acid for its potential benefits in areas like diabetes, Alzheimer's, and heart health.
Learn more about Ferulic AcidGinseng root is a well-loved ingredient in Asian skincare for good reason. It hydrates the skin, soothes irritation, and helps even out skin tone.
In traditional East Asian medicine, ginseng has been used for centuries both as food and as a healing remedy, and modern research continues to confirm its skin benefits.
One of the standout features of ginseng is its ability to improve blood circulation and oxygen delivery to the skin, bringing a fresh supply of nutrients to support overall skin health. It also has antioxidant and anti-inflammatory properties. This helps to protect your skin against damage from UV exposure, pollution, and daily stress.
Additionally, studies suggest that ginseng may help reduce hyperpigmentation by inhibiting tyrosinase, the enzyme involved in melanin production.
There are different types of ginseng used in skincare, and while they all share core benefits, their potency can vary.
Most products use fresh or white ginseng because it’s more affordable. However, red ginseng, produced by steaming the root, contains higher levels of ginsenosides, which are compounds with proven anti-aging effects. These ginsenosides help reduce the appearance of wrinkles and improve skin elasticity.
Note: All forms of ginseng are listed simply as “Panax ginseng” in ingredient lists. We recommend reaching out to the brand if you have questions about which type of ginseng is used in their ingredients.
For general antioxidant benefits, any ginseng extract will do, but for wrinkle care or firmer skin, red or fermented ginseng is often more effective.
In short, ginseng is a powerhouse ingredient that supports hydration, radiance, and resilience.
Learn more about Panax Ginseng Root ExtractCamellia Sinensis Leaf Extract (tea extract) is one of the most well-researched plant extracts in skincare with an impressive resume.
Black tea, green tea, and oolong tea are all harvested from the Camellia Sinensis plant.
Studies show green tea extract and its catechins (like epigallocatechin gallate (EGCG)) help your skin cells product energy more efficiently and reducing the number of free-radicals that can damage your skin from the inside.
In lab-grown skin models, this translated to younger, healthier, and stronger skin.
There's also good sun protection data; researchers saw less DNA damage and redness on human skin when green tea was applied before UVB exposure. And the more they applied, the better the protection.
Needless to say, this ingredient shouldn't replace your sunscreen. But it is a great supportive ingredient that you can already find in many sunscreens and antioxidant serums.
A 2009 study found a 2% green tea lotion was effective for mild-to-moderate acne thanks to its anti-inflammatory and mild antimicrobial activity.
The quality of the extract matters a lot here:
Good extracts contain 50-90% catechins while lower quality ones are mostly there for marketing. We recommend reaching out to the brand if you have questions about the quality or source of their ingredients.
Human Repeated Insult Patch Testing showed no irritation or sensitization at use concentrations (0.86% in leave-on products and up to 30% as leaf water).
Learn more about Camellia Sinensis Leaf ExtractPolysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.
It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.
The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.
Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).
True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.
Because it is derived from lauric acid, it may not be fungal acne safe.
Learn more about Polysorbate 20Chances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt. This ingredient has many purposes in skincare: thickener, emulsifier, and exfoliator.
You'll most likely find this ingredient in cleansers where it is used to create a gel-like texture. As an emulsifier, it also prevents ingredients from separating.
You might see people debate whether Sodium Chloride is comedogenic, but there actually haven't been any comedogenic tests done on it. Either way, the overall formulation of a product matters a lot more than any single ingredient.
You might see this ingredient used in scrubs as a primary exfoliating ingredient.
Learn more about Sodium ChlorideHydroxyacetophenone is antioxidant with skin conditioning and soothing properties. It also boosts the efficiency of preservatives.
Though naturally occuring in Norwegian spruce needles, this ingredient is usually synthetically created.
This ingredient is not irritating or sensitizing. Recent research also suggests it may have skin-brightening effects through tyrosinase inhibition.
Learn more about HydroxyacetophenonePolyquaternium-10 is an ammonium salt of hydroxyethylcellulose. It is a white and granular powder used as a film-former and anti-static agent.
This ingredient is commonly found in hair conditioning products. According to a manufacturer, its positive charge makes it great for absorbing hair proteins. The manufacturer also states this ingredient helps with curl retention.
For haircare friends: this ingredient is not a silicone.
Learn more about Polyquaternium-10Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid or alcohol, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl Glycol1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Glyceryl Oleate is the ester of glycerin and oleic acid. This ingredient is mainly an emollient and emulsifier.
Emollients soften and hydrate the skin by creating a thin film on top to trap in moisture. As an emulsifier, glyceryl oleate helps stabilize formulations by preventing ingredients such as oil and water from separating. According to a manufacturer, this ingredient helps helps thicken water-in-oil formulations, shower gels, and hair shampoos.
In some products, this ingredient may be used as a fragrance / perfuming ingredient. The scent of this ingredient is described to be "waxy".
Glyceryl oleate is created from oils rich in oleic acid, such as peanut oil and olive oil.
This ingredient may not be malassezia folliculitis safe.
Learn more about Glyceryl OleateSorbeth-230 Tetraoleate isn't fungal acne safe.
Tetrasodium Glutamate Diacetate is a chelating agent. Chelating agents help prevent metal ions from binding to other ingredients. This helps prevent unwanted effects and reactions from a product. These metal ions may come from water and are found in miniscule amounts.
Tetrasodium Glutamate Diacetate can also help other preservatives be more effective.
Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideTocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolWe don't have a description for Hydrogenated Vegetable Glycerides Citrate yet.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Limonene is a fragrance that adds scent and taste to a formulation.
It's found in the peel oil of citrus fruits and other plants such as lavender and eucalyptus. The scent of limonene is generally described as "sweet citrus".
Limonene acts as an antioxidant, meaning it helps neutralize free radicals.
When exposed to air, oxidized limonene may sensitize the skin. Because of this, limonene is often avoided by people with sensitive skin.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.
Learn more about LimoneneReviews
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Where it's from
Advanced Clinicals is a American brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Published March 18, 2025 • Added by enitanlawal