Versus

Galderma Differin Cream Versus La Roche-Posay Retinol B3 Serum

Prescription
Serum
Swiss Brand Switzerland
French Brand France

Updated on January 20, 2025

Overview

Cool Features

They both contain retinoid

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing and better texture

Free From

They both do not contain any common allergens or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

Galderma Differin Cream 10 ingredients

La Roche-Posay Retinol B3 Serum 22 ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Galderma Differin Cream 10 ingredients

La Roche-Posay Retinol B3 Serum 22 ingredients

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

When to use

Galderma Differin Cream 10 ingredients

La Roche-Posay Retinol B3 Serum 22 ingredients

234 Routines
7% use in am
93% use in pm
73% use every day
When to use See routines that use it ->
366 Routines
6% use in am
94% use in pm
61% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Galderma Differin Cream 10 ingredients

4.5 /5
from 4 ratings
Works Well (4) No Scent (3) Absorbs Well (2)
ChienYun_CY's avatar

Chien Yun Ang

10 months ago
Review

This cream is prescribed to me and I LOVE it. It isn't drying for me and I don't suffer any side effects from using it. I only need a fairly thin layer of this cream on my affected areas. It cleared up most possible developing whiteheads for me and leave my skin really bright and even.

#absorbs well
#no scent
#works well
Khang69's avatar

K

3 months ago
Review

I used this as a spot treatment for my stubborn/hidden acne and allergy pimples. It works great and the result might be visible after 1 or 2 days of use. The problem is it burned the area when I applied the cream with redness, it took weeks to get rid of the redness

#great value
#absorbs well
#no scent
#works well

La Roche-Posay Retinol B3 Serum 22 ingredients

3.4 /5
from 5 ratings
Expensive (2) Absorbs Well (2) Works Well (2)
Lapaki's avatar

Lapaki

2 years ago
Review

Very good and gentle retinol serum
My retinol journey began with this gentle serum with a concentration of 0.3% retinol: 0.1% pure retinol combined with 0.2% retinol palmitate that ensures gradual release of the active ingredients. It din't irritate my skin or cause any major break-outs, just some slight purging in the beginning, but that is concidered a normal reaktion that fades as soon as the Show more

carolperroud's avatar

carolperroud

2 years ago
Review

Breakout
I woke up with oily skin and bumps after using this product