What's inside
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Skin ConditioningSimmondsia Chinensis Seed Oil
EmollientPolysorbate 80
EmulsifyingGlycerin
HumectantCarthamus Tinctorius Seed Oil
MaskingSodium Hyaluronate
HumectantButylene Glycol
HumectantCamellia Sinensis Leaf Extract
AntimicrobialCitric Acid
BufferingRetinyl Palmitate
Skin ConditioningPropylene Glycol
HumectantPolysorbate 20
EmulsifyingCarbomer
Emulsion StabilisingTripeptide-1
Skin ConditioningPhenoxyethanol
PreservativeEthylhexylglycerin
Skin ConditioningHexapeptide-9
Skin ConditioningAcetyl Hexapeptide-7
Skin ProtectingAcetyl Hexapeptide-1
Skin ConditioningAluminum Acetate Solution
AstringentHexapeptide-35
Skin ConditioningTocopherol
AntioxidantAscorbic Acid
AntioxidantCollagen
MoisturisingPalmitoyl Pentapeptide-4
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningPalmitoyl Tripeptide-5
Skin ConditioningAluminum Diacetate
Antimicrobial1,2-Hexanediol
Skin ConditioningHexapeptide-2
BleachingAcetyl Hexapeptide-8
HumectantCopper Tripeptide-1
Skin ConditioningPalmitoyl Tripeptide-1
Skin ConditioningAcetyl Tetrapeptide-5
HumectantWater, Simmondsia Chinensis Seed Oil, Polysorbate 80, Glycerin, Carthamus Tinctorius Seed Oil, Sodium Hyaluronate, Butylene Glycol, Camellia Sinensis Leaf Extract, Citric Acid, Retinyl Palmitate, Propylene Glycol, Polysorbate 20, Carbomer, Tripeptide-1, Phenoxyethanol, Ethylhexylglycerin, Hexapeptide-9, Acetyl Hexapeptide-7, Acetyl Hexapeptide-1, Aluminum Acetate Solution, Hexapeptide-35, Tocopherol, Ascorbic Acid, Collagen, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-5, Aluminum Diacetate, 1,2-Hexanediol, Hexapeptide-2, Acetyl Hexapeptide-8, Copper Tripeptide-1, Palmitoyl Tripeptide-1, Acetyl Tetrapeptide-5
Acetyl Hexapeptide-8
HumectantCopper Tripeptide-1
Skin ConditioningPalmitoyl Pentapeptide-4
Skin ConditioningAcetyl Tetrapeptide-2
Skin ConditioningAcetyl Tetrapeptide-5
HumectantTocopheryl Acetate
AntioxidantAscorbic Acid
AntioxidantCamellia Sinensis Leaf Extract
AntimicrobialCollagen
MoisturisingCarthamus Tinctorius Seed Oil
MaskingPalmitoyl Tetrapeptide-7
Skin ConditioningPalmitoyl Tripeptide-1
Skin ConditioningHyaluronic Acid
HumectantSimmondsia Chinensis Seed Oil
EmollientAcetyl Hexapeptide-8, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Acetyl Tetrapeptide-2, Acetyl Tetrapeptide-5, Tocopheryl Acetate, Ascorbic Acid, Camellia Sinensis Leaf Extract, Collagen, Carthamus Tinctorius Seed Oil, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Hyaluronic Acid, Simmondsia Chinensis Seed Oil
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
The comparison to Botox does have limits because the molecule is water-loving and relatively large.
Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
Learn more about Acetyl Hexapeptide-8Acetyl Tetrapeptide-5 is a peptide that goes by another name, eyeseryl, due to claims that it can help reduce eye puffiness.
The manufacturer claims this ingredient reduces eye puffiness by:
An in-vivo study from the manufacturer found 95% of volunteers saw eye bag improvement by the end of the study.
Eye puffiness is caused by two major factors: fluid retention and fat.
Those with fluid retention may see improvement from using this ingredient. However, those with eye fat will need surgical intervention in order to get rid of puffiness.
Learn more about Acetyl Tetrapeptide-5Ascorbic Acid is is pure Vitamin C and is the biologically active form used directly by skin.
Not only is vitamin C great for your overall health and immune system, but it also has plenty of benefits for your skin. It is best supported by academic literature for:
Topical vitamin C has been shown to help neutralize oxidative stress from UV and pollution, helping to improve photoaging and hyperpigmentation when used consistently.
One clinical study found that using 5% topical vitamin C for six months improved signs of photodamaged skin, both on the surface and in the deeper structural layers of the skin.
While vitamin C doesn’t replace sunscreen, studies show it can boost photoprotection when combined with Vitamin E and ferulic acid. These two ingredients help improve stability and protective effects.
The big downside of this ingredient is formulation difficulty. Vitamin C is prone to oxidation and doesn't penetrate the skin unless formulated correctly. Research found that vitamin C absorbs into the skin best at a low pH (< 3.5) with about 20% being the upper limit for effective absorption.
Skin levels can saturate after repeated application; this means your skin won’t keep absorbing more once it’s full of vitamin C. This is why more isn’t always better with vitamin C and why very high concentrations don’t necessarily give extra benefits.
Ascorbic acid generally works well with many skincare ingredients but can be irritating when combined with other active ingredients. Strong oxidizing acne treatments like benzoyl peroxide can reduce the effectiveness of vitamin C if they are used at the same time; they are often recommended for use at different times of day.
Read more about other types of Vitamin C:
Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.
Learn more about Ascorbic AcidCamellia Sinensis Leaf Extract (tea extract) is one of the most well-researched plant extracts in skincare with an impressive resume.
Black tea, green tea, and oolong tea are all harvested from the Camellia Sinensis plant.
Studies show green tea extract and its catechins (like epigallocatechin gallate (EGCG)) help your skin cells product energy more efficiently and reducing the number of free-radicals that can damage your skin from the inside.
In lab-grown skin models, this translated to younger, healthier, and stronger skin.
There's also good sun protection data; researchers saw less DNA damage and redness on human skin when green tea was applied before UVB exposure. And the more they applied, the better the protection.
Needless to say, this ingredient shouldn't replace your sunscreen. But it is a great supportive ingredient that you can already find in many sunscreens and antioxidant serums.
A 2009 study found a 2% green tea lotion was effective for mild-to-moderate acne thanks to its anti-inflammatory and mild antimicrobial activity.
The quality of the extract matters a lot here:
Good extracts contain 50-90% catechins while lower quality ones are mostly there for marketing. We recommend reaching out to the brand if you have questions about the quality or source of their ingredients.
Human Repeated Insult Patch Testing showed no irritation or sensitization at use concentrations (0.86% in leave-on products and up to 30% as leaf water).
Learn more about Camellia Sinensis Leaf ExtractCarthamus Tinctorius Seed Oil comes from the seeds of the safflower plant. It is a skin conditioning agent that helps soften skin and keep it hydrated.
This seed oil has an unusual fatty acid profile: it is one of the highest linoleic acid plant oils out there (~55-77%). It also has low amounts of oleic acid, and this high-linoleic/low-oleic ratio gets people excited.
Linoleic acid helps maintain skin barrier integrity and is a building block for the ceramides in your stratum corneum. Notably, people with acne tend to have lower linoleic acid in their skin lipids as well (and this gets worse as acne gets more severe).
Overall, it's a lightweight, fast-absorbing oil that has a long safety track record. Lab testing has found it to be non-irritating for skin or eyes.
The Malassezia yeast can metabolize the fatty acids in this oil to grow; therefore this ingredient may not be fungal acne safe.
Learn more about Carthamus Tinctorius Seed OilCollagen is a big structural protein that your body uses to keep skin firm and bouncy. Despite the marketing, topically applied collagen doesn't "refill" the collagen in your skin.
The molecule is too big to pass through your skin barrier so intact Collagen physically can't get past the surface.
What it actually does in your skincare is work as a humectant and film-former: it binds water, lays down a light moisturizing film, and reduces water loss from the surface. This helps make skin feel smoother and temporarily plumper.
This ingredient has been found safe for use in cosmetics with clinical studies showing no irritation, sensitization, or phototoxicity. It's typically used at low concentrations (often a fraction of a percent up to a few percent).
Collagen will not increase sun sensitivity, but you should always wear sunscreen during the day.
Learn more about hydrolyzed collagen or soluble collagen.
Learn more about CollagenCopper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.
It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.
While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.
Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.
Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.
Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.
For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.
After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.
While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.
Read more about other common types of peptides here:
Learn more about Copper Tripeptide-1You might know this ingredient as Matrixyl. It is a synthetic peptide made up of five amino acids attached to a palmitic acid, a fatty acid that helps it absorb into skin more easily.
As a signal peptide, Matrixyl acts like a little messenger. Once it reaches your skin cells, it tells them to ramp up production of collagen, elastin, and other proteins that keep skin looking firm and smooth.
A 12 week clinical study found that a moisturizer containing just 3 ppm of Matrixyl led to a significant improvement in fine-lines and wrinkles. Another study showed an 18% reduction in wrinkle depth, 37% reduction in wrinkle thickness, and a 21% improvement in skin firmness after just 28 days of twice-daily use.
The coolest part is that it works at incredibly low concentrations (like 0.0003%) and it plays well with other actives.
The CIR (Cosmetic Ingredient Review) panel found it to be non-sensitizing across multiple tests and human patch tests also showed no irritation or sensitization.
Fun fact: Matrixyl was originally developed by French company Sederma and Procter & Gamble.
Read more about other common types of peptides here:
Learn more about Palmitoyl Pentapeptide-4Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging".
"Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age.
This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break down collagen and elastin.
Clinical testing showed statistically significant improvements in:
Studies also found the more of this ingredient used, the more your skin produces Collagen I, fibronectin, and hyaluronic acid.
You'll likely see this ingredient paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.
A 3% concentration applied twice daily for two months showed meaningful skin rejuvenation results in clinical panels.
Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.
Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.
That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.
Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.
In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.
Human clinical data is promising, but modest:
A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.
A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.
You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.
Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.
Jojoba oil is one of the most well-studied plant-derived ingredients in cosmetics. It is an emollient with a special structure.
Because it is made up of 97-98% wax esters, it closely mirrors the linear monoesters found in human sebum. This makes it skin compatible, non-greasy, and lightweight.
Unlike other plant oils, jojoba wax doesn't easily penetrate skin. It mostly works in the uppermost layers as an emollient. This just means it forms a light barrier on the skin to help retain moisture.
Formulations with jojoba esters up to 90% reduced transepidermal water loss (TEWL) and increased barrier recovery by 81% (outperforming bisabolol at 47%).
Besides barrier support, the science also suggests jojoba to have anti-inflammatory effects and potential applications for skin infections, aging, and wound healing.
Fun fact: Indigenous cultures have used jojoba as a moisturizer and to help treat burns for centuries.
Fungal acne: The Malassezia yeast is known to metabolize fatty acids in the C11-24 range and jojoba's dominant fatty acid components fall into this range. This ingredient may not be fungal acne safe.
Learn more about Simmondsia Chinensis Seed Oil