Updated on May 16, 2024
Overview
Cool Features
They both contain retinoid
Suited For
They're both likely to be good for fighting acne and anti aging
Free From
They both do not contain any harsh alcohols, common allergens, oils or sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients
Avène Cleanance Smoothing Night Cream 34 ingredients
At a glance
Click on any of the items below to learn more
Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients
Avène Cleanance Smoothing Night Cream 34 ingredients
Notable Ingredients
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Benefits
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Concerns
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Notable Ingredients
This product contains 1 ingredient that may have this attribute:
Benefits
This product contains 1 ingredient that may have this attribute:
This product contains 1 ingredient that may have this attribute:
This product contains 1 ingredient that may have this attribute:
This product contains 1 ingredient that may have this attribute:
This product contains 1 ingredient that may have this attribute:
This product contains 1 ingredient that may have this attribute:
This product contains 1 ingredient that may have this attribute:
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Concerns
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Ingredients Side-by-side
2 Benefits 2 Concerns
Adapalene is a type of retinoid and common acne treatment.
Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
Paraben 2 Concerns
Methylparaben is a preservative and is a paraben. It is used to prevent the growth of fungus, mold, and other harmful bacteria. Parabens are chemicals used as preservatives in both cosmetics and food.
Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Caprylic Acid is a fatty acid commonly found in plant oils, such as palm and coconut oils.
Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.
Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
Glyceryl Stearate is a mix of glycerin and stearic acid.
Peg-100 Stearate is an emollient and emulsifier. PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.
Another popular name for this ingredient is Synovea HR. This ingredient is a skin lightener and antioxidant.
1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.
Algin is brown algae. Algae is an informal term for a group of aquatic organisms that can photosynthesize. It is estimated there are at least 30,000 types of Algae.
Arachidyl Alcohol is a fatty alcohol made from peanut oil. It is an emollient, emulsifier, and thickener.
A type of fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product. They are usually derived from natural fats and oils and therefore do not have the same drying or irritating effect as traditional alcohols.
May worsen Eczema
Benzoic Acid is used to preserve and adjust the pH of products.
This BHA stands for butylated hydroxyanisole. If you are looking for the beta-hydroxy acid, aka as Salicylic Acid, click here.
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
Dimethicone Crosspolymer is a silicone created by modifying dimethicone with hydrocarbon side chains. Due to its large size, it does not penetrate skin. It is considered non-occlusive.
Dimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.
2 Concerns
Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Hydrogenated Polyisobutene is a synthetic polymer. Polymers are compounds with high molecular weight. Hydrogenated Polyisobutene is an emollient and texture enhancer.
Buddleja Davidii Extract is native to China and Japan. It is also known as the Butterfly Bush as it provides food for butterflies.
This helper ingredient is a surfactant and emulsifier. It is created from coconut alcohol.
7 Benefits 3 Concerns
Retinal is a form of retinoid. Retinoids are the gold-standard class of anti-aging ingredients.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
Sorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.
Stearyl Alcohol is a type of fatty alcohol from stearic acid. It is a white, waxy compound used to emulsify ingredients.
Ci 77891 is a white pigment from Titanium dioxide. It is naturally found in minerals such as rutile and ilmenite.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
Water, Caprylic Acid, Isododecane, Dimethicone, Glycerin, Pentylene Glycol, Propylene Glycol, Squalane, Glyceryl Stearate, Peg-100 Stearate, Hexylresorcinol, 1,2-Hexanediol, Algin, Arachidyl Alcohol, Arachidyl Glucoside, Behenyl Alcohol, Benzoic Acid, BHA, Caprylyl Glycol, Carbomer, Dimethicone Crosspolymer, Dimethiconol, Parfum, Hydrogenated Polyisobutene, 2-Hydroxyethyl Acrylate, Buddleja Davidii Extract, Peg-7 Trimethylolpropane Coconut Ether, CI 17200, Retinal, Sodium Hydroxide, Sorbitan Isostearate, Stearyl Alcohol, CI 77891, Xanthan Gum
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
Carbomer is commonly found in many types of cosmetics products. It is found to be safe in concentrations up to 15%. However, a high amount of carbomer can cause pilling or balling up of products. Most products contain 1% of less of carbomer.
Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.
Another role of this ingredient is preventing a product from melting or freezing. Propylene glycol also adds antimicrobrial properties to a product, elongating product lifespan.
This ingredient is considered an organic alcohol and commonly added into both cosmetics and foods.
Those with sensitive skin or conditions may deliver a rash when using this ingredient.
Learn more about Propylene GlycolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideIngredient Ratings
Here's what our community thinks of the ingredients in these two products.
When to use
Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients
Avène Cleanance Smoothing Night Cream 34 ingredients
Reviews
Here's what our community thinks
Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients
BrittBrine
This has probably been the product that has made the most difference in my skin. It's clearing up breakouts and acne that I've had for the longest...
This has probably been the product that has made the most difference in my skin. It's clearing up breakouts and acne that I've had for the longest time. My skin looks and feels so much better and I've only been using it for about 2-3 months now.
jojoswrld_
Works! Doesn’t irritate my skin when used on a dry surface. I hate how my skin looks when it sends all the clogged sebum to the surface of my skin,...
Works! Doesn’t irritate my skin when used on a dry surface. I hate how my skin looks when it sends all the clogged sebum to the surface of my skin, but it clears over time and leaves the skin incredibly firm and smooth. It’s the only not cruelty-free product I use just because it’s benefitted me so greatly and, in my opinion, is indisputably the best prescription-grade retinoid especially for sensitive skin.
