What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Aloe Barbadensis Leaf Extract
EmollientPropanediol
SolventGlycerin
HumectantPalmitoyl Tripeptide-1
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningAcetyl Hexapeptide-8
HumectantNiacinamide
Smoothing1,2-Hexanediol
Skin ConditioningSodium Hyaluronate
HumectantBeta-Glucan
Skin ConditioningAdenosine
Skin ConditioningButylene Glycol
HumectantAllantoin
Skin ConditioningRosa Damascena Extract
MaskingLavandula Angustifolia Flower Extract
CleansingCamellia Sinensis Leaf Extract
AntimicrobialMelissa Officinalis Leaf Extract
Skin ConditioningArtemisia Vulgaris Extract
Skin ConditioningAloe Barbadensis Leaf Extract, Propanediol, Glycerin, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Acetyl Hexapeptide-8, Niacinamide, 1,2-Hexanediol, Sodium Hyaluronate, Beta-Glucan, Adenosine, Butylene Glycol, Allantoin, Rosa Damascena Extract, Lavandula Angustifolia Flower Extract, Camellia Sinensis Leaf Extract, Melissa Officinalis Leaf Extract, Artemisia Vulgaris Extract
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
The comparison to Botox does have limits because the molecule is water-loving and relatively large.
Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
Learn more about Acetyl Hexapeptide-8