Mizon Bio Hyaluronic Acid Ampoule
A ampoule with 17 ingredients, including hyaluronic acid and peptides.
Overview
What it is
Ampoule with 17 ingredients that contains hyaluronic acid and peptides
Cool Features
It is cruelty-free and reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, sensitive skin, scar healing and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, parabens, silicones or sulfates
Fun facts
Mizon is from South Korea.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin ConditioningGlycerin
HumectantMethylpropanediol
Solvent1,2-Hexanediol
Skin ConditioningSalvia Hispanica Seed Extract
EmollientCentella Asiatica Extract
CleansingHouttuynia Cordata Extract
Skin ConditioningPEG-60 Hydrogenated Castor Oil
EmulsifyingSodium Hyaluronate
HumectantPropanediol
SolventEthylhexylglycerin
Skin ConditioningButylene Glycol
HumectantDisodium EDTA
Silkworm Cocoon Extract
HumectantPalmitoyl Tripeptide-5
Skin ConditioningPhenoxyethanol
PreservativeParfum
MaskingWater, Glycerin, Methylpropanediol, 1,2-Hexanediol, Salvia Hispanica Seed Extract, Centella Asiatica Extract, Houttuynia Cordata Extract, PEG-60 Hydrogenated Castor Oil, Sodium Hyaluronate, Propanediol, Ethylhexylglycerin, Butylene Glycol, Disodium EDTA, Silkworm Cocoon Extract, Palmitoyl Tripeptide-5, Phenoxyethanol, Parfum
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinMethylpropanediol is a synthetic solvent and humectant.
As a solvent, it helps dissolve other ingredients, helping to evenly distribute ingredients throughout the product. This ingredient has also been shown to have antimicrobial properties which makes it a preservative booster.
Methylpropanediol is able to add a bit of moisture to the skin. It also helps other ingredients be better absorbed into the skin, such as salicylic acid.
Learn more about Methylpropanediol1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Ā
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesĀ
This ingredient comes from chia seeds (the same ones you put in your smoothie!). It has emollient and skin conditioning properties due to its rich concentration of linoleic acid and polyunsaturated fatty acids.
One small clinical study of 10 people found that a 4% chia seed oil formulation significantly improved skin hydration and soothed itchiness in 8 weeks. Another study showed using a chia seed extract enriched with vitamin F told skin cells to produce more of their own hydration factors.
There's also some lab evidence that chia seed extract, when paired with pomegranate extract, may help reduce excess pigment production.
Learn more about Salvia Hispanica Seed ExtractCentella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.
Centella is rich in antioxidants and amino acids, such as Madecassic Acid and Asiaticoside.
Studies show the compounds in centella help with:
The combination of all these properties makes centella effective at soothing, hydrating, and protecting the skin.
Other great components of centella include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.
Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Learn more about Centella Asiatica ExtractHouttuynia Cordata Extract is more commonly known as Heart Leaf, Fish Mint, or Chameleon plant.
The components found in Heart Leaf give it antioxidant, hydrating, antimicrobial, and anti-inflammatory properties.
Heart Leaf is rich in flavonoids such as quercetin, apigenin, and more. It also contains polysaccharides, the most common type of carbs in food.
Flavonoids have been shown to be effective antioxidants. They help neutralize free-radical molecules. Free-radical molecules are unstable molecules that may damage our skin cells and DNA. The flavonoids in Heart Leaf also help soothe the skin.
Polysaccharides are naturally found in our skin. They play a role in hydrating and repairing the top layer of skin. The polysaccharides in Heart Leaf help moisturize our skin.
Studies show decanoyl acetaldehyde, a component of Heart Leaf oil, is effective at killing bacteria.
The name 'Fish Mint' comes from the herb's natural fishy smell. Is is native to southeast Asia and used throughout the continent for traditional cooking and medicine.
Learn more about Houttuynia Cordata ExtractPeg-60 Hydrogenated Castor Oil comes from hydrogenated castor oil. It is a solubilizer and emulsifier.
As a solubilizer, it helps dissolve ingredients into a water-based version. It is also an emulsifer. Emulsifier help prevent oils and water from separating. Both these properties help create evenly-spread and uniform products.
Basically, Peg-60 Hydrogenated Castor Oil helps hold ingredients together.
Learn more about PEG-60 Hydrogenated Castor OilSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronatePropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.Ā
Itās often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAWe don't have a description for Silkworm Cocoon Extract yet.
Palmitoyl Tripeptide-5 is a synthetic signal lipopeptide. This just means it is a three amino acid chain bolted onto a palmitic acid tail so it can slip through the skin's lipid barrier.
This peptide has a "build more, lose less" approach.
It's designed to mimic the collagen-stimulating activity in your skin by copying a snippet of one of your skin's own matrix proteins. This nudges fibroblasts into making more collagen while inhibiting the enzyme that breaks down skin protein.
The manufacturer's in vivo study of 45 volunteers found 1% and 2.5% reduced the appearance of wrinkles by 7% and 12% respectively, after using it twice daily for 84 days.
This is in the expected range for peptides; they're slow and cumulative actives and not overnight fixers.
Typical use levels range from 1-3% and this ingredient gets along with pretty much everything.
On the fungal acne front:
Although palmitic acid sits in the chain length that Malassezia can feed on, this ingredient has it locked in an amine bond. This makes it hard for Malassezia to access as a source of food, and therefore fungal acne safe.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of āFRAGRANCEā or āPARFUMā according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumReviews
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Where it's from
Mizon is a Korean brand
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The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about usĀ· Updated February 12, 2025 • Added by aimansoherwardi