La Clinica Essentials Pure Retinol In Luxurious Plant Oils
A serum with 19 ingredients, including retinoid and vitamin E.
Overview
What it is
Serum with 19 ingredients that contains retinoid and Vitamin E
Cool Features
It is cruelty-free and reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, parabens, silicones or sulfates
Fun facts
La Clinica is from Australia. This product is used in 3 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Squalane
EmollientSimmondsia Chinensis Seed Oil
EmollientC13-15 Alkane
SolventVitis Vinifera Oil
PerfumingCaprylyl Caprylate/Caprate
EmollientCaprylic/Capric Triglyceride
MaskingChamomilla Recutita Extract
Skin ConditioningCalendula Officinalis Extract
Skin ConditioningTocopheryl Acetate
AntioxidantOctyldodecanol
EmollientRibes Nigrum Seed Oil
EmollientHelianthus Annuus Seed Oil Unsaponifiables
EmollientCardiospermum Halicacabum Flower/Leaf/Vine Extract
Skin ConditioningTocopherol
AntioxidantHelianthus Annuus Seed Oil
EmollientRosmarinus Officinalis Leaf Extract
AntimicrobialRetinol 1%
Skin ConditioningTetrahydropiperine
Skin ConditioningDimethylmethoxy Chromanol
AntioxidantSqualane, Simmondsia Chinensis Seed Oil, C13-15 Alkane, Vitis Vinifera Oil, Caprylyl Caprylate/Caprate, Caprylic/Capric Triglyceride, Chamomilla Recutita Extract, Calendula Officinalis Extract, Tocopheryl Acetate, Octyldodecanol, Ribes Nigrum Seed Oil, Helianthus Annuus Seed Oil Unsaponifiables, Cardiospermum Halicacabum Flower/Leaf/Vine Extract, Tocopherol, Helianthus Annuus Seed Oil, Rosmarinus Officinalis Leaf Extract, Retinol 1%, Tetrahydropiperine, Dimethylmethoxy Chromanol
Key Ingredients
Benefits
Concerns
Ingredients Explained
Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Learn more about SqualaneJojoba oil is one of the most well-studied plant-derived ingredients in cosmetics. It is an emollient with a special structure.
Because it is made up of 97-98% wax esters, it closely mirrors the linear monoesters found in human sebum. This makes it skin compatible, non-greasy, and lightweight.
Unlike other plant oils, jojoba wax doesn't easily penetrate skin. It mostly works in the uppermost layers as an emollient. This just means it forms a light barrier on the skin to help retain moisture.
Formulations with jojoba esters up to 90% reduced transepidermal water loss (TEWL) and increased barrier recovery by 81% (outperforming bisabolol at 47%).
Besides barrier support, the science also suggests jojoba to have anti-inflammatory effects and potential applications for skin infections, aging, and wound healing.
Fun fact: Indigenous cultures have used jojoba as a moisturizer and to help treat burns for centuries.
Due to its fatty acid content, Jojoba oil may not be fungal acne safe.
Learn more about Simmondsia Chinensis Seed OilC13-15 Alkane is a group of alkanes with 13 to 15 carbon atoms in the alkyl chain.
It is a solvent and texture enhancer. Solvents are used to keep ingredients together in a product. They can help dissolve ingredients to stable bases or help evenly distribute ingredients throughout the product.
Vitis Vinifera Oil comes from grapes.
This ingredient is used to add a scent or to cover another scent. Perfuming ingredients can be natural or synthetically created.
Caprylyl Caprylate/Caprate is a synthetic blend of caprylic acid and capric acid.
As an emollient, this ingredient helps moisturize the skin. Emollients create a barrier on the skin that prevents water from escaping.
This ingredient is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid. Though it behaves like an oil, it is not technically one due to its chemical composition. It is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Be sure to patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
Learn more about Caprylic/Capric TriglycerideThis ingredient comes from the Chamomile flower.
Chamomile is rich in antioxidants and has anti-inflammatory properties. Several compounds found in chamomile help with soothing, such as bisbolol.
Antioxidant components in chamomile help fight free-radical molecules. These unstable molecules may damage your skin cells. By stabilizing them, antioxidants may help reduce the signs of aging.
Ancient Greeks, Romans, and Egyptians used Chamomile to treat skin redness and dryness. Chamomile has also been used to help with stomach issues.
Learn more about Chamomilla Recutita ExtractCalendula Officinalis Extract comes from the common Marigold plant.
Marigold flowers contain flavonoids. Flavonoids are a group of substances found naturally in plants. They possess antioxidant and inflammation properties.
This ingredient may help soothe your skin by reducing inflammation. Emerging studies show it inhibits nitrous oxide production safely, therefore reducing inflammation.
Marigolds have been used in traditional medicine throughout Asia and Europe.
Learn more about Calendula Officinalis ExtractTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateOctyldodecanol is a fatty alcohol sourced from plant oils like coconut or palm (or made synthetically).
It is:
You'll likely see this in many BHA products because this is the go-to solvent for salicylic acid.
This ingredient is typically used at levels between 2-20%.
Regarding fungal acne:
In 2019, this ingredient was tested against multiple Malassezia species (the yeast that causes fungal acne) and showed no growth.
Ribes Nigrum Seed Oil is oil from the seeds of Black Currant. A more common name for this ingredient is Black Currant Seed Oil.
Black Currant Seed Oil contains a high amount of omega-6 and omega-3 fatty acids. It also contains linoleic acid.
Black currant berries contain anthocyanins, an antioxidant. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
Black currant berries also contain Vitamin E and fatty acids. It can help soften the skin.
Learn more about Ribes Nigrum Seed OilSunflower seed oil unsaponifiables comes from the the small part of sunflower seed oil that does not convert into soap during the saponification process.
This ingredient is rich in vitamin E, fatty acids (like linoleic acid), and other lipophilic compounds, making it a great emollient. Emollients help keep the skin hydrated and soft.
Due to its rich fatty acid content, this ingredient may not be Malassezia folliculitis safe.
Learn more about Helianthus Annuus Seed Oil UnsaponifiablesCardiospermum halicacabum extract is more commonly known as Balloon Vine Extract.
Balloon Vine Extract helps soothe skin and is an antioxidant. It also contains many fatty acids, such as palmitic, oleic, and stearic acids. While these fatty acids help soften skin, they may not be fungal-friendly.
Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
Balloon Vine has been used in traditional medicine in many Asian cultures.
Learn more about Cardiospermum Halicacabum Flower/Leaf/Vine ExtractTocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolHelianthus Annuus Seed Oil is a plant oil derived from the seeds of a sunflower.
It is rich in fatty acids, primarily linoleic acid and oleic acid. This gives it emollient and skin conditioning properties.
The reason this ingredient is so effective is because it forms a thin film on the skin that reduces transepidermal water loss (TEWL) while supplying linoleic acid to the stratum corneum to improve barrier strength.
The high linoleic acid content is particularly noteworthy for acne-prone skin.
Research suggests that acne-prone skin tends to be deficient in linoleic acid in sebum. Topical application may help replenish this to support a healthier follicular environment and less comedone-promoting sebum.
One randomized study found sunflower seed oil preserved skin barrier integrity in adult volunteers with and without atopic dermatitis (outperforming olive oil).
This ingredient is well-studied, gentle, and an effective emollient suitable for most skin types.
On fungal acne: This ingredient may not be Fungal acne (Malassezia folliculitis) safe. This is because it contains fatty acids with carbon chain lengths in the C11-C24 range.
Learn more about Helianthus Annuus Seed OilRosmarinus Officinalis Leaf Extract comes from rosemary. Rosemary is native to the Mediterranean.
While Rosmarinus Officinalis Leaf Oil can be volatile due to its fragrant properties, the fragrance components are usually removed in the leaf extract.
Rosemary Leaf Extract contains many antioxidants such as rosmarinic acid and caffeic acid. Rosemarinic acid, a compound found in rosemary leaf, has been found to help soothe skin conditions such as eczema and acne.
Learn more about Rosmarinus Officinalis Leaf ExtractRetinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
Why is retinol famous?
It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.
Retinol is proven to:
This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.
Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).
Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
We recommend speaking with a medical professional about using this ingredient during pregnancy.
Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.
Read about Tretinoin
Learn more about RetinolWe don't have a description for Tetrahydropiperine yet.
Dimethylmethoxy Chromanol is an antioxidant.
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Where it's from
La Clinica is a Australian brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated April 14, 2026 • Added by jnm