Vichy Liftactiv Supreme HA Epidermic Filler Serum Versus Vichy Liftactiv B3 Serum Dark Spots & Wrinkles
What's inside
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
HumectantHydroxyethylpiperazine Ethane Sulfonic Acid
BufferingSodium Hyaluronate
HumectantPEG-60 Hydrogenated Castor Oil
EmulsifyingWater, Glycerin, Hydroxyethylpiperazine Ethane Sulfonic Acid, Sodium Hyaluronate, PEG-60 Hydrogenated Castor Oil, Secale Cereale Seed Extract, Calcium Pantothenate, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Phenoxyethanol, Chlorphenesin, Ascorbyl Glucoside, Disodium EDTA, Pentylene Glycol, Ceramide AP
Water
Skin ConditioningButylene Glycol
HumectantNiacinamide
SmoothingHydroxyethylpiperazine Ethane Sulfonic Acid
BufferingGlycerin
HumectantHydroxyethyl Urea
HumectantPropylene Glycol
HumectantGlycolic Acid
BufferingTranexamic Acid
AstringentAllantoin
Skin ConditioningSodium Hydroxide
BufferingPhenoxyethanol
PreservativeChlorphenesin
AntimicrobialAscorbyl Glucoside
AntioxidantCaprylyl Glycol
EmollientHydrolyzed Rice Protein
Skin ConditioningVitreoscilla Ferment
Skin ConditioningTrisodium Ethylenediamine Disuccinate
Xanthan Gum
EmulsifyingPentylene Glycol
Skin ConditioningWater, Butylene Glycol, Niacinamide, Hydroxyethylpiperazine Ethane Sulfonic Acid, Glycerin, Hydroxyethyl Urea, Propylene Glycol, Glycolic Acid, Tranexamic Acid, Allantoin, Sodium Hydroxide, Phenoxyethanol, Chlorphenesin, Ascorbyl Glucoside, Caprylyl Glycol, Hydrolyzed Rice Protein, Vitreoscilla Ferment, Trisodium Ethylenediamine Disuccinate, Xanthan Gum, Pentylene Glycol
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Ascorbyl Glucoside (AA-2G) is one of the most stable vitamin C derivatives out there.
It's made by attaching a glucose molecule to ascorbic acid; this glucose "cap" shields the vitamin C from air, light, heat, and metal ions that normally cause pure ascorbic acid to oxidize.
Once on your skin, the enzyme alpha-glucosidase snips off the glucose and gradually releases active ascorbic acid right where it's needed. Basically, it behaves like a slow-release pro-vitamin C with less of a stinging that high-strength ascorbic acid can cause.
The research supports the classic vitamin C benefits as well. In lab and human studies, AA-2G slowed down the skin's production of melanin (the pigment behind dark spots) and helped shield skin cells against sun damage better than ascorbyl phosphate.
These studies also showed AA-2G released vitamin C over a longer period.
A frequently cited manufacturer trial found that a 2% AA-2G face cream significantly improved wrinkle depth and skin roughness after 45 days.
And in 2009, a clinical trial showed it meaningfully lightened dark patches on the gums compared to a placebo.
There's also collagen-synthesis support (since vitamin C is a required cofactor for that) and an antioxidant effect too.
Typical usage is usually between 0.5-5% and most studies/products land around 2%.
AA-2G performs best when formulated at a mildly acidic pH (~5-7) which is much gentler than the pH that pure vitamin C demands (~2.5-3.5).
Just one thing worth knowing: the in-skin conversation rate is only about 55-60% by weight. So a 5% AA-2G product delivers roughly 2.75-3% of actual active vitamin C. On top of that, skin absorption is relatively low because the ingredient is water-soluble.
Learn more about Ascorbyl GlucosideChlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.
Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria.
Chlorphenesin is soluble in both water and glycerin.
Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.
Learn more about ChlorphenesinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinWe don't have a description for Hydroxyethylpiperazine Ethane Sulfonic Acid yet.
Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolPhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water